Randomized Trial of TAS-102 for Refractory Metastatic Colorectal Cancer
Mayer, Robert J, Van Cutsem, Eric, Falcone, Alfredo, Yoshino, Takayuki, Garcia-Carbonero, Rocio, Mizunuma, Nobuyuki, Yamazaki, Kentaro, Shimada, Yasuhiro, Tabernero, Josep, Komatsu, Yoshito, Sobrero, Alberto, Boucher, Eveline, Peeters, Marc, Tran, Ben, Lenz, Heinz-Josef, Zaniboni, Alberto, Hochster, Howard, Cleary, James M, Prenen, Hans, Benedetti, Fabio, Mizuguchi, Hirokazu, Makris, Lukas, Ito, Masanobu, Ohtsu, Atsushi
Published in The New England journal of medicine (14.05.2015)
Published in The New England journal of medicine (14.05.2015)
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Journal Article
Phase III HEAT Study Adding Lyso-Thermosensitive Liposomal Doxorubicin to Radiofrequency Ablation in Patients with Unresectable Hepatocellular Carcinoma Lesions
Tak, Won Young, Lin, Shi-Ming, Wang, Yijun, Zheng, Jiasheng, Vecchione, Aldo, Park, Soo Young, Chen, Min Hua, Wong, Stephen, Xu, Ruocai, Peng, Cheng-Yuan, Chiou, Yi-You, Huang, Guan-Tarn, Cai, Jianqiang, Abdullah, Basri Johan Jeet, Lee, June Sung, Lee, Jae Young, Choi, Jong-Young, Gopez-Cervantes, Julieta, Sherman, Morris, Finn, Richard S, Omata, Masao, O'Neal, Michael, Makris, Lukas, Borys, Nicholas, Poon, Ronnie, Lencioni, Riccardo
Published in Clinical cancer research (01.01.2018)
Published in Clinical cancer research (01.01.2018)
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Journal Article
Body weight loss as a prognostic and predictive factor in previously treated patients with metastatic gastric cancer: post hoc analyses of the randomized phase III TAGS trial
Ghidini, Michele, Hochster, Howard, Doi, Toshihiko, Van Cutsem, Eric, Makris, Lukas, Takahashi, Osamu, Benhadji, Karim A., Mansoor, Wasat
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.07.2023)
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.07.2023)
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Journal Article
Efficacy and safety of trifluridine/tipiracil in older and younger patients with metastatic gastric or gastroesophageal junction cancer: subgroup analysis of a randomized phase 3 study (TAGS)
Shitara, Kohei, Doi, Toshihiko, Hosaka, Hisashi, Thuss-Patience, Peter, Santoro, Armando, Longo, Federico, Ozyilkan, Ozgur, Cicin, Irfan, Park, David, Zaanan, Aziz, Pericay, Carles, Özgüroğlu, Mustafa, Alsina, Maria, Makris, Lukas, Benhadji, Karim A., Ilson, David H.
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.05.2022)
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.05.2022)
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Journal Article
A phase 2 trial of trifluridine/tipiracil plus nivolumab in patients with heavily pretreated microsatellite‐stable metastatic colorectal cancer
Patel, Manish R., Falchook, Gerald S., Hamada, Kensuke, Makris, Lukas, Bendell, Johanna C.
Published in Cancer medicine (Malden, MA) (01.02.2021)
Published in Cancer medicine (Malden, MA) (01.02.2021)
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Journal Article
Trifluridine/tipiracil in patients with metastatic gastroesophageal junction cancer: a subgroup analysis from the phase 3 TAGS study
Mansoor, Wasat, Arkenau, Hendrik-Tobias, Alsina, Maria, Shitara, Kohei, Thuss-Patience, Peter, Cuffe, Sinead, Dvorkin, Mikhail, Park, David, Ando, Takayuki, Van Den Eynde, Marc, Beretta, Giordano D., Zaniboni, Alberto, Doi, Toshihiko, Tabernero, Josep, Ilson, David H., Makris, Lukas, Benhadji, Karim A., Van Cutsem, Eric
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.07.2021)
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.07.2021)
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Journal Article
A phase I, open-label, single-dose study to evaluate the effect of hepatic impairment on the pharmacokinetics and safety of futibatinib
Gao, Ling, Yamamiya, Ikuo, Pinti, Mark, Rondon, Juan Carlos, Marbury, Thomas, Tomlinson, Gareth, Makris, Lukas, Hangai, Nanae, Wacheck, Volker
Published in Clinical and translational science (01.09.2023)
Published in Clinical and translational science (01.09.2023)
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Journal Article
A randomized, phase 2 study of deoxyuridine triphosphatase inhibitor, TAS-114, in combination with S-1 versus S-1 alone in patients with advanced non-small-cell lung cancer
Yamamoto, Nobuyuki, Hayashi, Hidetoshi, Planchard, David, Morán, Teresa, Gregorc, Vanesa, Dowell, Jonathan, Sakai, Hiroshi, Yoh, Kiyotaka, Nishio, Makoto, Cortot, Alexis B., Benhadji, Karim A., Soni, Nital, Huang, Jinhong, Makris, Lukas, Cedres, Susana
Published in Investigational new drugs (01.10.2020)
Published in Investigational new drugs (01.10.2020)
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Journal Article
A phase 2 randomized study of TAS-102 versus topotecan or amrubicin in patients requiring second-line chemotherapy for small cell lung cancer refractory or sensitive to frontline platinum-based chemotherapy
Scagliotti, Giorgio, PhD, Nishio, Makoto, MD, Satouchi, Miyako, PhD, Valmadre, Giuseppe, MD, Niho, Seiji, Galetta, Domenico, Cortinovis, Diego, MD, Benedetti, Fabio, MD, Yoshihara, Eiji, Makris, Lukas, PhD, Inoue, Akira, PhD, Kubota, Kaoru, PhD
Published in Lung cancer (Amsterdam, Netherlands) (01.10.2016)
Published in Lung cancer (Amsterdam, Netherlands) (01.10.2016)
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Journal Article
Abstract 10818: Lomitapide Observational Worldwide Evaluation Registry (LOWER): One-Year Data
Blom, Dirk, Kastelein, John J, Larrey, Dominique, Makris, Lukas, Schwamlein, Charles, Phillips, Helen, Bloedon, LeAnne, Underberg, James
Published in Circulation (New York, N.Y.) (10.11.2015)
Published in Circulation (New York, N.Y.) (10.11.2015)
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Journal Article
LOWER, a registry of lomitapide-treated patients with homozygous familial hypercholesterolemia: Rationale and design
Blom, Dirk J., MD, PhD, Fayad, Zahi A., BSEE, MSE, PhD, Kastelein, John J.P., MD, PhD, Larrey, Dominique, MD, PhD, Makris, Lukas, BS, MS, PhD, Schwamlein, Charles, MD, MPH, Bloeden, LeAnne, BS, MS, RD, Underberg, James, MS, MD
Published in Journal of clinical lipidology (01.03.2016)
Published in Journal of clinical lipidology (01.03.2016)
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Journal Article
Trifluridine/tipiracil versus placebo in patients with heavily pretreated metastatic gastric cancer (TAGS): a randomised, double-blind, placebo-controlled, phase 3 trial
Shitara, Kohei, Doi, Toshihiko, Dvorkin, Mikhail, Mansoor, Wasat, Arkenau, Hendrik-Tobias, Prokharau, Aliaksandr, Alsina, Maria, Ghidini, Michele, Faustino, Catia, Gorbunova, Vera, Zhavrid, Edvard, Nishikawa, Kazuhiro, Hosokawa, Ayumu, Yalçın, Şuayib, Fujitani, Kazumasa, Beretta, Giordano D, Cutsem, Eric Van, Winkler, Robert E, Makris, Lukas, Ilson, David H, Tabernero, Josep
Published in The lancet oncology (01.11.2018)
Published in The lancet oncology (01.11.2018)
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Journal Article
The long-term, real-world effectiveness and safety of lomitapide in homozygous familial hypercholesterolaemia (HoFH): Nine-year data from the lomitapide observational worldwide evaluation registry (lower)
Blom, Dirk, Underberg, James, Cannon, Christopher, Larrey, Dominique, Makris, Lukas, O'Brien, Sallyann
Published in Atherosclerosis (01.08.2024)
Published in Atherosclerosis (01.08.2024)
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Journal Article
Long-term safety and efficacy of lomitapide in patients with homozygous familial hypercholesterolemia: Five-year data from the Lomitapide Observational Worldwide Evaluation Registry (LOWER)
Underberg, James A., Cannon, Christopher P., Larrey, Dominique, Makris, Lukas, Blom, Dirk, Phillips, Helen
Published in Journal of clinical lipidology (01.11.2020)
Published in Journal of clinical lipidology (01.11.2020)
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Journal Article
PEMDA-HN, an open-label, phase II, randomized controlled study of danvatirsen plus pembrolizumab compared to pembrolizumab alone in first-line recurrent and/or metastatic head and neck squamous cell carcinoma (RM HNSCC)
Posner, Marshall R., Wong, Deborah J.L., Harrington, Kevin Joseph, O'Neal, Richard Lee, Makris, Lukas, Perdomini, Morgane, MacIntyre, Susan, Denker, Andrew, Saba, Nabil F.
Published in Journal of clinical oncology (01.06.2024)
Published in Journal of clinical oncology (01.06.2024)
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Journal Article
The Lomitapide Observational Worldwide Evaluation Registry (LOWER) - Nine-year Effectiveness and Safety Data in HoFH
Underberg, James, Cannon, Christopher, Larrey, Dominique, Makris, Lukas, O'Brien, Sallyann, Blom, Dirk
Published in Journal of clinical lipidology (01.07.2024)
Published in Journal of clinical lipidology (01.07.2024)
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Journal Article
LONG-TERM SAFETY AND EFFICACY OF LOMITAPIDE IN PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA: FIVE-YEAR DATA FROM THE LOMITAPIDE OBSERVATIONAL WORLDWIDE EVALUATION REGISTRY (LOWER)
Underberg, James A., Cannon, Christopher P., Larrey, Dominique, Makris, Lukas, Phillips, Helen, Blom, Dirk
Published in Journal of the American College of Cardiology (24.03.2020)
Published in Journal of the American College of Cardiology (24.03.2020)
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Journal Article
The subgroups of the phase III RECOURSE trial of trifluridine/tipiracil (TAS-102) versus placebo with best supportive care in patients with metastatic colorectal cancer
Van Cutsem, Eric, Mayer, Robert J., Laurent, Stéphanie, Winkler, Robert, Grávalos, Cristina, Benavides, Manuel, Longo-Munoz, Federico, Portales, Fabienne, Ciardiello, Fortunato, Siena, Salvatore, Yamaguchi, Kensei, Muro, Kei, Denda, Tadamichi, Tsuji, Yasushi, Makris, Lukas, Loehrer, Patrick, Lenz, Heinz-Josef, Ohtsu, Atsushi
Published in European journal of cancer (1990) (01.02.2018)
Published in European journal of cancer (1990) (01.02.2018)
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Abstract CT016: Clinical activity of single-agent ZN-c3, an oral WEE1 inhibitor, in a phase 1 dose-escalation trial in patients with advanced solid tumors
Tolcher, Anthony, Mamdani, Hirva, Chalasani, Pavani, Meric-Bernstam, Funda, Gazdoiu, Mihaela, Makris, Lukas, Pultar, Philippe, Voliotis, Dimitris
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Body weight loss (BWL) as a prognostic/predictive factor in previously treated patients (pts) with metastatic gastric or gastroesophageal junction cancer (mGC/GEJC): Post-hoc analyses of the phase III tags trial
Ghidini, Michele, Hochster, Howard S., Doi, Toshihiko, Van Cutsem, Eric, Makris, Lukas, Benhadji, Karim A., Mansoor, Wasat
Published in Journal of clinical oncology (20.01.2021)
Published in Journal of clinical oncology (20.01.2021)
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