In Silico Fragment-Based Design Identifies Subfamily B1 Metallo-β-lactamase Inhibitors
Cain, Ricky, Brem, Jürgen, Zollman, David, McDonough, Michael A, Johnson, Rachel M, Spencer, James, Makena, Anne, Abboud, Martine I, Cahill, Samuel, Lee, Sook Y, McHugh, Peter J, Schofield, Christopher J, Fishwick, Colin W. G
Published in Journal of medicinal chemistry (08.02.2018)
Published in Journal of medicinal chemistry (08.02.2018)
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Journal Article
Biochemical characterization of New Delhi metallo-β-lactamase variants reveals differences in protein stability
Makena, Anne, Brem, Jürgen, Pfeffer, Inga, Geffen, Rebecca E J, Wilkins, Sarah E, Tarhonskaya, Hanna, Flashman, Emily, Phee, Lynette M, Wareham, David W, Schofield, Christopher J
Published in Journal of antimicrobial chemotherapy (01.02.2015)
Published in Journal of antimicrobial chemotherapy (01.02.2015)
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Journal Article
Comparison of Verona Integron-Borne Metallo-β-Lactamase (VIM) Variants Reveals Differences in Stability and Inhibition Profiles
Makena, Anne, Düzgün, Azer Ö, Brem, Jürgen, McDonough, Michael A, Rydzik, Anna M, Abboud, Martine I, Saral, Ayşegül, Çiçek, Ayşegül Ç, Sandalli, Cemal, Schofield, Christopher J
Published in Antimicrobial agents and chemotherapy (01.03.2016)
Published in Antimicrobial agents and chemotherapy (01.03.2016)
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Journal Article
19F‐NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo‐β‐Lactamase
Abboud, Martine I., Hinchliffe, Philip, Brem, Jürgen, Macsics, Robert, Pfeffer, Inga, Makena, Anne, Umland, Klaus‐Daniel, Rydzik, Anna M., Li, Guo‐Bo, Spencer, James, Claridge, Timothy D. W., Schofield, Christopher J.
Published in Angewandte Chemie International Edition (27.03.2017)
Published in Angewandte Chemie International Edition (27.03.2017)
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Journal Article
19F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-[beta]-Lactamase
Abboud, Martine I, Hinchliffe, Philip, Brem, Jurgen, Macsics, Robert, Pfeffer, Inga, Makena, Anne, Umland, Klaus-Daniel, Rydzik, Anna M, Li, Guo-Bo, Spencer, James, Claridge, Timothy D W, Schofield, Christopher J
Published in Angewandte Chemie International Edition (27.03.2017)
Published in Angewandte Chemie International Edition (27.03.2017)
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Journal Article
Cover Picture: Monitoring Conformational Changes in the NDM-1 Metallo-β-lactamase by 19F NMR Spectroscopy (Angew. Chem. Int. Ed. 12/2014)
Rydzik, Anna M., Brem, Jürgen, van Berkel, Sander S., Pfeffer, Inga, Makena, Anne, Claridge, Timothy D. W., Schofield, Christopher J.
Published in Angewandte Chemie International Edition (17.03.2014)
Published in Angewandte Chemie International Edition (17.03.2014)
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Journal Article
Cover Picture: Monitoring Conformational Changes in the NDM‐1 Metallo‐β‐lactamase by 19 F NMR Spectroscopy (Angew. Chem. Int. Ed. 12/2014)
Rydzik, Anna M., Brem, Jürgen, van Berkel, Sander S., Pfeffer, Inga, Makena, Anne, Claridge, Timothy D. W., Schofield, Christopher J.
Published in Angewandte Chemie International Edition (17.03.2014)
Published in Angewandte Chemie International Edition (17.03.2014)
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Journal Article
Cover Picture: Monitoring Conformational Changes in the NDM-1 Metallo-[beta]-lactamase by 19FNMR Spectroscopy (Angew. Chem. Int. Ed. 12/2014)
Rydzik, Anna M, Brem, Jurgen, vanBerkel, Sander S, Pfeffer, Inga, Makena, Anne, Claridge, Timothy D W, Schofield, Christopher J
Published in Angewandte Chemie International Edition (17.03.2014)
Published in Angewandte Chemie International Edition (17.03.2014)
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Journal Article
Monitoring Conformational Changes in the NDM-1 Metallo-[beta]-lactamase by 19FNMR Spectroscopy
Rydzik, Anna M, Brem, Jurgen, vanBerkel, Sander S, Pfeffer, Inga, Makena, Anne, Claridge, Timothy D W, Schofield, Christopher J
Published in Angewandte Chemie International Edition (17.03.2014)
Published in Angewandte Chemie International Edition (17.03.2014)
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Journal Article
Monitoring Conformational Changes in the NDM‐1 Metallo‐β‐lactamase by 19 F NMR Spectroscopy
Rydzik, Anna M., Brem, Jürgen, van Berkel, Sander S., Pfeffer, Inga, Makena, Anne, Claridge, Timothy D. W., Schofield, Christopher J.
Published in Angewandte Chemie International Edition (17.03.2014)
Published in Angewandte Chemie International Edition (17.03.2014)
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Journal Article
Monitoring Conformational Changes in the NDM-1 Metallo-[beta]-lactamase by super(19)FNMR Spectroscopy
Rydzik, Anna M, Brem, Juergen, vanBerkel, Sander S, Pfeffer, Inga, Makena, Anne, Claridge, Timothy DW, Schofield, Christopher J
Published in Angewandte Chemie International Edition (01.03.2014)
Published in Angewandte Chemie International Edition (01.03.2014)
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Journal Article
19 F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-β-Lactamase
Abboud, Martine I, Hinchliffe, Philip, Brem, Jürgen, Macsics, Robert, Pfeffer, Inga, Makena, Anne, Umland, Klaus-Daniel, Rydzik, Anna M, Li, Guo-Bo, Spencer, James, Claridge, Timothy D W, Schofield, Christopher J
Published in Angewandte Chemie International Edition (27.03.2017)
Published in Angewandte Chemie International Edition (27.03.2017)
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Journal Article
Biochemical characterization of New Delhi metallo-[Beta]-lactamase variants reveals differences in protein stability
Makena, Anne, Brem, Jürgen, Pfeffer, Inga, Geffen, Rebecca E J, Wilkins, Sarah E, Tarhonskaya, Hanna, Flashman, Emily, Phee, Lynette M, Wareham, David W, Schofield, Christopher J
Published in Journal of antimicrobial chemotherapy (01.02.2015)
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Published in Journal of antimicrobial chemotherapy (01.02.2015)
Journal Article
Chromophore-Linked Substrate (CLS405): Probing Metallo-β-Lactamase Activity and Inhibition
Makena, Anne, van Berkel, Sander S., Lejeune, Clarisse, Owens, Raymond J., Verma, Anil, Salimraj, Ramya, Spencer, James, Brem, Jürgen, Schofield, Christopher J.
Published in ChemMedChem (01.12.2013)
Published in ChemMedChem (01.12.2013)
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Journal Article
Monitoring Conformational Changes in the NDM-1 Metallo-β-lactamase by 19F NMR Spectroscopy
Rydzik, Anna M., Brem, Jürgen, van Berkel, Sander S., Pfeffer, Inga, Makena, Anne, Claridge, Timothy D. W., Schofield, Christopher J.
Published in Angewandte Chemie International Edition (17.03.2014)
Published in Angewandte Chemie International Edition (17.03.2014)
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Journal Article
Cover Picture: Chromophore-Linked Substrate (CLS405): Probing Metallo-[beta]-Lactamase Activity and Inhibition (ChemMedChem 12/2013)
Makena, Anne, vanBerkel, Sander S, Lejeune, Clarisse, Owens, Raymond J, Verma, Anil, Salimraj, Ramya, Spencer, James, Brem, Jurgen, Schofield, Christopher J
Published in ChemMedChem (01.12.2013)
Published in ChemMedChem (01.12.2013)
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Journal Article
Chromophore-Linked Substrate (CLS405): Probing Metallo-[beta]-Lactamase Activity and Inhibition
Makena, Anne, vanBerkel, Sander S, Lejeune, Clarisse, Owens, Raymond J, Verma, Anil, Salimraj, Ramya, Spencer, James, Brem, Jurgen, Schofield, Christopher J
Published in ChemMedChem (01.12.2013)
Published in ChemMedChem (01.12.2013)
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Journal Article
Cover Picture: Chromophore-Linked Substrate (CLS405): Probing Metallo-β-Lactamase Activity and Inhibition (ChemMedChem 12/2013)
Makena, Anne, van Berkel, Sander S., Lejeune, Clarisse, Owens, Raymond J., Verma, Anil, Salimraj, Ramya, Spencer, James, Brem, Jürgen, Schofield, Christopher J.
Published in ChemMedChem (01.12.2013)
Published in ChemMedChem (01.12.2013)
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Journal Article