Tutorial: a guide to performing polygenic risk score analyses
Choi, Shing Wan, Mak, Timothy Shin-Heng, O’Reilly, Paul F.
Published in Nature protocols (01.09.2020)
Published in Nature protocols (01.09.2020)
Get full text
Journal Article
Rapid Identification of Pathogenic Variants in Two Cases of Charcot-Marie-Tooth Disease by Gene-Panel Sequencing
Ho, Chi-Chun, Tai, Shuk-Mui, Lee, Edmond Chi-Nam, Mak, Timothy Shin-Heng, Liu, Timothy Kam-Tim, Tang, Victor Wai-Lun, Poon, Wing-Tat
Published in International journal of molecular sciences (05.04.2017)
Published in International journal of molecular sciences (05.04.2017)
Get full text
Journal Article
Trans-Ethnic Polygenic Analysis Supports Genetic Overlaps of Lumbar Disc Degeneration With Height, Body Mass Index, and Bone Mineral Density
Zhou, Xueya, Cheung, Ching-Lung, Karasugi, Tatsuki, Karppinen, Jaro, Samartzis, Dino, Hsu, Yi-Hsiang, Mak, Timothy Shin-Heng, Song, You-Qiang, Chiba, Kazuhiro, Kawaguchi, Yoshiharu, Li, Yan, Chan, Danny, Cheung, Kenneth Man-Chee, Ikegawa, Shiro, Cheah, Kathryn Song-Eng, Sham, Pak Chung
Published in Frontiers in genetics (03.08.2018)
Published in Frontiers in genetics (03.08.2018)
Get full text
Journal Article
Polygenic scores via penalized regression on summary statistics
Mak, Timothy Shin Heng, Porsch, Robert Milan, Choi, Shing Wan, Zhou, Xueya, Sham, Pak Chung
Published in Genetic epidemiology (01.09.2017)
Published in Genetic epidemiology (01.09.2017)
Get full text
Journal Article
Reciprocal causation mixture model for robust Mendelian randomization analysis using genome-scale summary data
Liu, Zipeng, Qin, Yiming, Wu, Tian, Tubbs, Justin D., Baum, Larry, Mak, Timothy Shin Heng, Li, Miaoxin, Zhang, Yan Dora, Sham, Pak Chung
Published in Nature communications (28.02.2023)
Published in Nature communications (28.02.2023)
Get full text
Journal Article
Associations between CLU polymorphisms and memory performance: The role of serum lipids in Alzheimer's disease
Chen, Lu Hua, Heng Mak, Timothy Shin, Fan, Yanhui, Yin Ho, Deborah Tip, Sham, Pak Chung, Chu, Leung Wing, Song, You-Qiang
Published in Journal of psychiatric research (01.10.2020)
Published in Journal of psychiatric research (01.10.2020)
Get full text
Journal Article
Two-Stage Auction Mechanism for Long-Term Participation in Crowdsourcing
Mak, Timothy Shin Heng, Lam, Albert Y.S.
Published in IEEE transactions on computational social systems (01.06.2023)
Published in IEEE transactions on computational social systems (01.06.2023)
Get full text
Journal Article
Coverage and diagnostic yield of Whole Exome Sequencing for the Evaluation of Cases with Dilated and Hypertrophic Cardiomyopathy
Mak, Timothy Shin Heng, Lee, Yee-Ki, Tang, Clara S., Hai, JoJo S. H., Ran, Xinru, Sham, Pak-Chung, Tse, Hung-Fat
Published in Scientific reports (18.07.2018)
Published in Scientific reports (18.07.2018)
Get full text
Journal Article
Whole genome sequencing reveals epistasis effects within RET for Hirschsprung disease
Wang, Yanbing, Mak, Timothy Shin Heng, Dattani, Saloni, Garcia-Barcelo, Maria-Merce, Fu, Alexander Xi, Yip, Kevin Y., Ngan, Elly Sau-Wai, Tam, Paul Kwang-Hang, Tang, Clara Sze-Man, Sham, Pak Chung
Published in Scientific reports (28.11.2022)
Published in Scientific reports (28.11.2022)
Get full text
Journal Article
A guide to performing Polygenic Risk Score analyses
Choi, Shing Wan, Mak, Timothy Shin Heng, O’Reilly, Paul F.
Published in Nature protocols (24.07.2020)
Published in Nature protocols (24.07.2020)
Get full text
Journal Article
A powerful conditional gene-based association approach implicated functionally important genes for schizophrenia
Li, Miaoxin, Jiang, Lin, Mak, Timothy Shin Heng, Kwan, Johnny Sheung Him, Xue, Chao, Chen, Peikai, Leung, Henry Chi-Ming, Cui, Liqian, Li, Tao, Sham, Pak Chung
Published in Bioinformatics (15.02.2019)
Published in Bioinformatics (15.02.2019)
Get full text
Journal Article
EraSOR: a software tool to eliminate inflation caused by sample overlap in polygenic score analyses
Choi, Shing Wan, Mak, Timothy Shin Heng, Hoggart, Clive J, O'Reilly, Paul F
Published in Gigascience (28.12.2022)
Published in Gigascience (28.12.2022)
Get full text
Journal Article
Local True Discovery Rate Weighted Polygenic Scores Using GWAS Summary Data
Mak, Timothy Shin Heng, Kwan, Johnny Sheung Him, Campbell, Desmond Dedalus, Sham, Pak Chung
Published in Behavior genetics (01.07.2016)
Published in Behavior genetics (01.07.2016)
Get full text
Journal Article
EraSOR: Erase Sample Overlap in polygenic score analyses
Shing Wan Choi, Timothy Shin Heng Mak, Hoggart, Clive J, O'reilly, Paul F
Published in bioRxiv (13.12.2021)
Published in bioRxiv (13.12.2021)
Get full text
Paper