Cystathionine-β-Synthase: Molecular Regulation and Pharmacological Inhibition
Zuhra, Karim, Augsburger, Fiona, Majtan, Tomas, Szabo, Csaba
Published in Biomolecules (Basel, Switzerland) (30.04.2020)
Published in Biomolecules (Basel, Switzerland) (30.04.2020)
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Structural insight into the molecular mechanism of allosteric activation of human cystathionine β-synthase by S-adenosylmethionine
Ereño-Orbea, June, Majtan, Tomas, Oyenarte, Iker, Kraus, Jan P, Martínez-Cruz, Luis Alfonso
Published in Proceedings of the National Academy of Sciences - PNAS (16.09.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (16.09.2014)
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Overproduction of hydrogen sulfide, generated by cystathionine β-synthase, disrupts brain wave patterns and contributes to neurobehavioral dysfunction in a rat model of down syndrome
Panagaki, Theodora, Lozano-Montes, Laura, Janickova, Lucia, Zuhra, Karim, Szabo, Marcell P., Majtan, Tomas, Rainer, Gregor, Maréchal, Damien, Herault, Yann, Szabo, Csaba
Published in Redox biology (01.05.2022)
Published in Redox biology (01.05.2022)
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Catalytic specificity and crystal structure of cystathionine γ-lyase from Pseudomonas aeruginosa
Pedretti, Marco, Fernández-Rodríguez, Carmen, Conter, Carolina, Oyenarte, Iker, Favretto, Filippo, di Matteo, Adele, Dominici, Paola, Petrosino, Maria, Martinez-Chantar, Maria Luz, Majtan, Tomas, Astegno, Alessandra, Martínez-Cruz, Luis Alfonso
Published in Scientific reports (23.04.2024)
Published in Scientific reports (23.04.2024)
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Structural basis of regulation and oligomerization of human cystathionine β-synthase, the central enzyme of transsulfuration
Ereño-Orbea, June, Majtan, Tomas, Oyenarte, Iker, Kraus, Jan P, Martínez-Cruz, Luis Alfonso
Published in Proceedings of the National Academy of Sciences - PNAS (01.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (01.10.2013)
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Mechanism of action and impact of thiol homeostasis on efficacy of an enzyme replacement therapy for classical homocystinuria
Philipp, Thilo Magnus, Bottiglieri, Teodoro, Clapper, Wilmelenne, Liu, Kai, Rodems, Steve, Szabo, Csaba, Majtan, Tomas
Published in Redox biology (01.11.2024)
Published in Redox biology (01.11.2024)
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Thioethers as markers of hydrogen sulfide production in homocystinurias
Kožich, Viktor, Krijt, Jakub, Sokolová, Jitka, Melenovská, Petra, Ješina, Pavel, Vozdek, Roman, Majtán, Tomáš, Kraus, Jan P.
Published in Biochimie (01.07.2016)
Published in Biochimie (01.07.2016)
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Deciphering pathophysiological mechanisms underlying cystathionine beta-synthase-deficient homocystinuria using targeted metabolomics, liver proteomics, sphingolipidomics and analysis of mitochondrial function
Majtan, Tomas, Olsen, Thomas, Sokolova, Jitka, Krijt, Jakub, Křížková, Michaela, Ida, Tomoaki, Ditrói, Tamás, Hansikova, Hana, Vit, Ondrej, Petrak, Jiri, Kuchař, Ladislav, Kruger, Warren D., Nagy, Péter, Akaike, Takaaki, Kožich, Viktor
Published in Redox biology (01.07.2024)
Published in Redox biology (01.07.2024)
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Domain organization, catalysis and regulation of eukaryotic cystathionine beta-synthases
Majtan, Tomas, Pey, Angel L, Fernández, Roberto, Fernández, José A, Martínez-Cruz, Luis A, Kraus, Jan P
Published in PloS one (14.08.2014)
Published in PloS one (14.08.2014)
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Hypermethioninemia Leads to Fatal Bleeding and Increased Mortality in a Transgenic I278T Mouse Model of Homocystinuria
Park, Insun, Johnson, Linda K., Cox, Allaura, Branchford, Brian R., Paola, Jorge Di, Bublil, Erez M., Majtan, Tomas
Published in Biomedicines (24.07.2020)
Published in Biomedicines (24.07.2020)
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Salmonella enterica Serovar Kentucky: Antimicrobial Resistance and Molecular Analysis of Clinical Isolates from the Slovak Republic
Majtán, Viktor, Majtán, Tomáš, Majtán, Juraj, Szabóová, Monika, Majtánová, L’ubica
Published in Japanese Journal of Infectious Diseases (28.12.2006)
Published in Japanese Journal of Infectious Diseases (28.12.2006)
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