Pharmacological reduction of ER stress protects against TDP-43 neuronal toxicity in vivo
Vaccaro, Alexandra, Patten, Shunmoogum A, Aggad, Dina, Julien, Carl, Maios, Claudia, Kabashi, Edor, Drapeau, Pierre, Parker, J. Alex
Published in Neurobiology of disease (01.07.2013)
Published in Neurobiology of disease (01.07.2013)
Get full text
Journal Article
The Novel Small Molecule TRVA242 Stabilizes Neuromuscular Junction Defects in Multiple Animal Models of Amyotrophic Lateral Sclerosis
Bose, Poulomee, Tremblay, Elsa, Maios, Claudia, Narasimhan, Vijay, Armstrong, Gary A. B., Liao, Meijiang, Parker, J. Alex, Robitaille, Richard, Wen, Xiao Yan, Barden, Christopher, Drapeau, Pierre
Published in Neurotherapeutics (01.10.2019)
Published in Neurotherapeutics (01.10.2019)
Get full text
Journal Article
Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio
Vaccaro, Alexandra, Patten, Shunmoogum A, Ciura, Sorana, Maios, Claudia, Therrien, Martine, Drapeau, Pierre, Kabashi, Edor, Parker, J Alex
Published in PloS one (27.07.2012)
Published in PloS one (27.07.2012)
Get full text
Journal Article
Correction to: The Novel Small Molecule TRVA242 Stabilizes Neuromuscular Junction Defects in Multiple Animal Models of Amyotrophic Lateral Sclerosis
Bose, Poulomee, Tremblay, Elsa, Maios, Claudia, Narasimhan, Vijay, Armstrong, Gary A. B., Liao, Meijiang, Parker, J. Alex, Robitaille, Richard, Wen, Xiao Yan, Barden, Christopher, Drapeau, Pierre
Published in Neurotherapeutics (01.07.2021)
Published in Neurotherapeutics (01.07.2021)
Get full text
Journal Article
Modulating the endoplasmic reticulum stress response attenuates neurodegeneration in a Caenorhabditis elegans model of spinal muscular atrophy
Doyle, James J, Vrancx, Celine, Maios, Claudia, Labarre, Audrey, Patten, Shunmoogum A, Parker, J Alex
Published in Disease models & mechanisms (22.12.2020)
Published in Disease models & mechanisms (22.12.2020)
Get full text
Journal Article
Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis
Patten, Shunmoogum A, Aggad, Dina, Martinez, Jose, Tremblay, Elsa, Petrillo, Janet, Armstrong, Gary Ab, La Fontaine, Alexandre, Maios, Claudia, Liao, Meijiang, Ciura, Sorana, Wen, Xiao-Yan, Rafuse, Victor, Ichida, Justin, Zinman, Lorne, Julien, Jean-Pierre, Kabashi, Edor, Robitaille, Richard, Korngut, Lawrence, Parker, J Alexander, Drapeau, Pierre
Published in JCI insight (16.11.2017)
Published in JCI insight (16.11.2017)
Get full text
Journal Article
RNA-Based Therapy Utilizing Oculopharyngeal Muscular Dystrophy Transcript Knockdown and Replacement
Abu-Baker, Aida, Kharma, Nawwaf, Perreault, Jonathan, Grant, Alanna, Shekarabi, Masoud, Maios, Claudia, Dona, Michele, Neri, Christian, Dion, Patrick A., Parker, Alex, Varin, Luc, Rouleau, Guy A.
Published in Molecular therapy. Nucleic acids (15.04.2019)
Published in Molecular therapy. Nucleic acids (15.04.2019)
Get full text
Journal Article
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS
Hung, Shu-Ting, Linares, Gabriel R., Chang, Wen-Hsuan, Eoh, Yunsun, Krishnan, Gopinath, Mendonca, Stacee, Hong, Sarah, Shi, Yingxiao, Santana, Manuel, Kueth, Chuol, Macklin-Isquierdo, Samantha, Perry, Sarah, Duhaime, Sarah, Maios, Claudia, Chang, Jonathan, Perez, Joscany, Couto, Alexander, Lai, Jesse, Li, Yichen, Alworth, Samuel V., Hendricks, Eric, Wang, Yaoming, Zlokovic, Berislav V., Dickman, Dion K., Parker, J. Alex, Zarnescu, Daniela C., Gao, Fen-Biao, Ichida, Justin K.
Published in Cell (16.02.2023)
Published in Cell (16.02.2023)
Get full text
Journal Article
Chemical and genetic rescue of in vivo progranulin-deficient lysosomal and autophagic defects
Doyle, James J., Maios, Claudia, Vrancx, Céline, Duhaime, Sarah, Chitramuthu, Babykumari, Bennett, Hugh P. J., Bateman, Andrew, Parker, J. Alex
Published in Proceedings of the National Academy of Sciences - PNAS (22.06.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (22.06.2021)
Get full text
Journal Article
A single copy transgenic mutant FUS strain reproduces age-dependent ALS phenotypes in C. elegans
Labarre, Audrey, Tossing, Gilles, Maios, Claudia, Doyle, James J, Parker, J Alex
Published in microPublication biology (01.01.2021)
Published in microPublication biology (01.01.2021)
Get full text
Journal Article
De Novo Truncating Mutation in Kinesin 17 Associated with Schizophrenia
Tarabeux, Julien, Champagne, Nathalie, Brustein, Edna, Hamdan, Fadi F, Gauthier, Julie, Lapointe, Mathieu, Maios, Claudia, Piton, Amélie, Spiegelman, Dan, Henrion, Édouard, Millet, Bruno, Rapoport, Judith L, DeLisi, Lynn E, Joober, Ridha, Fathalli, Ferid, Fombonne, Éric, Mottron, Laurent, Forget-Dubois, Nadine, Boivin, Michel, Michaud, Jacques L, Lafrenière, Ronald G, Drapeau, Pierre, Krebs, Marie-Odile, Rouleau, Guy A
Published in Biological psychiatry (1969) (01.10.2010)
Published in Biological psychiatry (1969) (01.10.2010)
Get full text
Journal Article