Circulating and intrahepatic antiviral B cells are defective in hepatitis B
Burton, Alice R, Pallett, Laura J, McCoy, Laura E, Suveizdyte, Kornelija, Amin, Oliver E, Swadling, Leo, Alberts, Elena, Davidson, Brian R, Kennedy, Patrick Tf, Gill, Upkar S, Mauri, Claudia, Blair, Paul A, Pelletier, Nadege, Maini, Mala K
Published in The Journal of clinical investigation (01.10.2018)
Published in The Journal of clinical investigation (01.10.2018)
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Distinct Metabolic Requirements of Exhausted and Functional Virus-Specific CD8 T Cells in the Same Host
Schurich, Anna, Pallett, Laura J., Jajbhay, Danyal, Wijngaarden, Jessica, Otano, Itziar, Gill, Upkar S., Hansi, Navjyot, Kennedy, Patrick T., Nastouli, Eleni, Gilson, Richard, Frezza, Christian, Henson, Sian M., Maini, Mala K.
Published in Cell reports (Cambridge) (02.08.2016)
Published in Cell reports (Cambridge) (02.08.2016)
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Characterisation and induction of tissue-resident gamma delta T-cells to target hepatocellular carcinoma
Zakeri, Nekisa, Hall, Andrew, Swadling, Leo, Pallett, Laura J., Schmidt, Nathalie M., Diniz, Mariana O., Kucykowicz, Stephanie, Amin, Oliver E., Gander, Amir, Pinzani, Massimo, Davidson, Brian R., Quaglia, Alberto, Maini, Mala K.
Published in Nature communications (16.03.2022)
Published in Nature communications (16.03.2022)
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Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells
Pallett, Laura J, Gill, Upkar S, Quaglia, Alberto, Sinclair, Linda V, Jover-Cobos, Maria, Schurich, Anna, Singh, Kasha P, Thomas, Niclas, Das, Abhishek, Chen, Antony, Fusai, Giuseppe, Bertoletti, Antonio, Cantrell, Doreen A, Kennedy, Patrick T, Davies, Nathan A, Haniffa, Muzlifah, Maini, Mala K
Published in Nature medicine (01.06.2015)
Published in Nature medicine (01.06.2015)
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IL-10-producing regulatory B cells in the pathogenesis of chronic hepatitis B virus infection
Das, Abhishek, Ellis, Gidon, Pallant, Celeste, Lopes, A Ross, Khanna, Pooja, Peppa, Dimitra, Chen, Antony, Blair, Paul, Dusheiko, Geoffrey, Gill, Upkar, Kennedy, Patrick T, Brunetto, Maurizia, Lampertico, Pietro, Mauri, Claudia, Maini, Mala K
Published in The Journal of immunology (1950) (15.10.2012)
Published in The Journal of immunology (1950) (15.10.2012)
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Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection
Nebbia, Gaia, Peppa, Dimitra, Schurich, Anna, Khanna, Pooja, Singh, Harsimran D, Cheng, Yang, Rosenberg, William, Dusheiko, Geoffrey, Gilson, Richard, ChinAleong, Joanne, Kennedy, Patrick, Maini, Mala K
Published in PloS one (24.10.2012)
Published in PloS one (24.10.2012)
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Differential boosting of innate and adaptive antiviral responses during pegylated-interferon-alpha therapy of chronic hepatitis B
Micco, Lorenzo, Peppa, Dimitra, Loggi, Elisabetta, Schurich, Anna, Jefferson, Lucy, Cursaro, Carmela, Panno, Arianna Martello, Bernardi, Mauro, Brander, Christian, Bihl, Florian, Andreone, Pietro, Maini, Mala K
Published in Journal of hepatology (01.02.2013)
Published in Journal of hepatology (01.02.2013)
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Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint
Schmidt, Nathalie M., Wing, Peter A. C., Diniz, Mariana O., Pallett, Laura J., Swadling, Leo, Harris, James M., Burton, Alice R., Jeffery-Smith, Anna, Zakeri, Nekisa, Amin, Oliver E., Kucykowicz, Stephanie, Heemskerk, Mirjam H., Davidson, Brian, Meyer, Tim, Grove, Joe, Stauss, Hans J., Pineda-Torra, Ines, Jolly, Clare, Jury, Elizabeth C., McKeating, Jane A., Maini, Mala K.
Published in Nature communications (14.05.2021)
Published in Nature communications (14.05.2021)
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Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo
Gill, Upkar S, Peppa, Dimitra, Micco, Lorenzo, Singh, Harsimran D, Carey, Ivana, Foster, Graham R, Maini, Mala K, Kennedy, Patrick T F
Published in PLoS pathogens (01.08.2016)
Published in PLoS pathogens (01.08.2016)
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The third signal cytokine IL-12 rescues the anti-viral function of exhausted HBV-specific CD8 T cells
Schurich, Anna, Pallett, Laura J, Lubowiecki, Marcin, Singh, Harsimran D, Gill, Upkar S, Kennedy, Patrick T, Nastouli, Eleni, Tanwar, Sudeep, Rosenberg, William, Maini, Mala K
Published in PLoS pathogens (01.03.2013)
Published in PLoS pathogens (01.03.2013)
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Persistent symptoms after COVID-19 are not associated with differential SARS-CoV-2 antibody or T cell immunity
Altmann, Daniel M., Reynolds, Catherine J., Joy, George, Otter, Ashley D., Gibbons, Joseph M., Pade, Corinna, Swadling, Leo, Maini, Mala K., Brooks, Tim, Semper, Amanda, McKnight, Áine, Noursadeghi, Mahdad, Manisty, Charlotte, Treibel, Thomas A., Moon, James C., Boyton, Rosemary J.
Published in Nature communications (23.08.2023)
Published in Nature communications (23.08.2023)
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Adaptive Reconfiguration of Natural Killer Cells in HIV-1 Infection
Peppa, Dimitra, Pedroza-Pacheco, Isabela, Pellegrino, Pierre, Williams, Ian, Maini, Mala K, Borrow, Persephone
Published in Frontiers in immunology (16.03.2018)
Published in Frontiers in immunology (16.03.2018)
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Tissue CD14+CD8+ T cells reprogrammed by myeloid cells and modulated by LPS
Pallett, Laura J., Swadling, Leo, Diniz, Mariana, Maini, Alexander A., Schwabenland, Marius, Gasull, Adrià Dalmau, Davies, Jessica, Kucykowicz, Stephanie, Skelton, Jessica K., Thomas, Niclas, Schmidt, Nathalie M., Amin, Oliver E., Gill, Upkar S., Stegmann, Kerstin A., Burton, Alice R., Stephenson, Emily, Reynolds, Gary, Whelan, Matt, Sanchez, Jenifer, de Maeyer, Roel, Thakker, Clare, Suveizdyte, Kornelija, Uddin, Imran, Ortega-Prieto, Ana M., Grant, Charlotte, Froghi, Farid, Fusai, Giuseppe, Lens, Sabela, Pérez-del-Pulgar, Sofia, Al-Akkad, Walid, Mazza, Giuseppe, Noursadeghi, Mahdad, Akbar, Arne, Kennedy, Patrick T. F., Davidson, Brian R., Prinz, Marco, Chain, Benjamin M., Haniffa, Muzlifah, Gilroy, Derek W., Dorner, Marcus, Bengsch, Bertram, Schurich, Anna, Maini, Mala K.
Published in Nature (London) (09.02.2023)
Published in Nature (London) (09.02.2023)
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SARS-CoV-2-specific memory B cells can persist in the elderly who have lost detectable neutralizing antibodies
Jeffery-Smith, Anna, Burton, Alice R, Lens, Sabela, Rees-Spear, Chloe, Davies, Jessica, Patel, Monika, Gopal, Robin, Muir, Luke, Aiano, Felicity, Doores, Katie J, Chow, J Yimmy, Ladhani, Shamez N, Zambon, Maria, McCoy, Laura E, Maini, Mala K
Published in The Journal of clinical investigation (18.01.2022)
Published in The Journal of clinical investigation (18.01.2022)
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IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction
Easom, Nicholas J W, Stegmann, Kerstin A, Swadling, Leo, Pallett, Laura J, Burton, Alice R, Odera, Dennis, Schmidt, Nathalie, Huang, Wei-Chen, Fusai, Giuseppe, Davidson, Brian, Maini, Mala K
Published in Frontiers in immunology (09.05.2018)
Published in Frontiers in immunology (09.05.2018)
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Respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination
Mitsi, Elena, Diniz, Mariana O., Reiné, Jesús, Collins, Andrea M., Robinson, Ryan E., Hyder-Wright, Angela, Farrar, Madlen, Liatsikos, Konstantinos, Hamilton, Josh, Onyema, Onyia, Urban, Britta C., Solórzano, Carla, Belij-Rammerstorfer, Sandra, Sheehan, Emma, Lambe, Teresa, Draper, Simon J., Weiskopf, Daniela, Sette, Alessandro, Maini, Mala K., Ferreira, Daniela M.
Published in Nature communications (26.10.2023)
Published in Nature communications (26.10.2023)
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Human Liver Memory CD8+ T Cells Use Autophagy for Tissue Residence
Swadling, Leo, Pallett, Laura J., Diniz, Mariana O., Baker, Josephine M., Amin, Oliver E., Stegmann, Kerstin A., Burton, Alice R., Schmidt, Nathalie M., Jeffery-Smith, Anna, Zakeri, Nekisa, Suveizdyte, Kornelija, Froghi, Farid, Fusai, Giuseppe, Rosenberg, William M., Davidson, Brian R., Schurich, Anna, Simon, A. Katharina, Maini, Mala K.
Published in Cell reports (Cambridge) (21.01.2020)
Published in Cell reports (Cambridge) (21.01.2020)
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