Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells
Bolton-Gillespie, Elisabeth, Schemionek, Mirle, Klein, Hans-Ulrich, Flis, Sylwia, Hoser, Grazyna, Lange, Thoralf, Nieborowska-Skorska, Margaret, Maier, Jacqueline, Kerstiens, Linda, Koptyra, Mateusz, Müller, Martin C., Modi, Hardik, Stoklosa, Tomasz, Seferynska, Ilona, Bhatia, Ravi, Holyoake, Tessa L., Koschmieder, Steffen, Skorski, Tomasz
Published in Blood (16.05.2013)
Published in Blood (16.05.2013)
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The quantitative level of T315I mutated BCR-ABL predicts for major molecular response to second-line nilotinib or dasatinib treatment in patients with chronic myeloid leukemia
Lange, Thoralf, Ernst, Thomas, Gruber, Franz X, Maier, Jacqueline, Cross, Michael, Müller, Martin C, Niederwieser, Dietger, Hochhaus, Andreas, Pfirrmann, Markus
Published in Haematologica (Roma) (01.05.2013)
Published in Haematologica (Roma) (01.05.2013)
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JAK2 p.V617F allele burden in myeloproliferative neoplasms one month after allogeneic stem cell transplantation significantly predicts outcome and risk of relapse
Lange, T., Edelmann, A., Siebolts, U., Krahl, R., Nehring, C., Jakel, N., Cross, M., Maier, J., Niederwieser, D., Wickenhauser, C.
Published in Haematologica (Roma) (01.05.2013)
Published in Haematologica (Roma) (01.05.2013)
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A co-operative evaluation of different methods of detecting BCR-ABL kinase domain mutations in patients with chronic myeloid leukemia on second-line dasatinib or nilotinib therapy after failure of imatinib
Ernst, Thomas, Gruber, Franz X, Pelz-Ackermann, Oliver, Maier, Jacqueline, Pfirrmann, Markus, Muller, Martin C, Mikkola, Ingvild, Porkka, Kimmo, Niederwieser, Dietger, Hochhaus, Andreas, Lange, Thoralf
Published in Haematologica (Roma) (01.09.2009)
Published in Haematologica (Roma) (01.09.2009)
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Journal Article
Optimized Digital Droplet PCR for BCR-ABL
Maier, Jacqueline, Lange, Thoralf, Cross, Michael, Wildenberger, Kathrin, Niederwieser, Dietger, Franke, Georg-Nikolaus
Published in The Journal of molecular diagnostics : JMD (01.01.2019)
Published in The Journal of molecular diagnostics : JMD (01.01.2019)
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Comparison of Real-Time Quantitative PCR and Digital Droplet PCR for BCR-ABL1 Monitoring in Patients with Chronic Myeloid Leukemia
Franke, Georg-Nikolaus, Maier, Jacqueline, Wildenberger, Kathrin, Cross, Michael, Giles, Francis J., Müller, Martin C., Hochhaus, Andreas, Niederwieser, Dietger, Lange, Thoralf
Published in The Journal of molecular diagnostics : JMD (01.01.2020)
Published in The Journal of molecular diagnostics : JMD (01.01.2020)
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Journal Article
Detection of Mutant Free Circulating Tumor DNA in the Plasma of Patients with Gastrointestinal Stromal Tumor Harboring Activating Mutations of CKIT or PDGFRA
MAIER, Jacqueline, LANGE, Thoralf, VON BUBNOFF, Nikolas, KERLE, Irina, SPECHT, Katja, BRUEGEL, Melanie, WICKENHAUSER, Claudia, JOST, Philipp, NIEDERWIESER, Dietger, PESCHEL, Christian, DUYSTER, Justus
Published in Clinical cancer research (01.09.2013)
Published in Clinical cancer research (01.09.2013)
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Circulating cKIT and PDGFRA DNA indicates disease activity in Gastrointestinal Stromal Tumor (GIST)
Jilg, Stefanie, Rassner, Michael, Maier, Jacqueline, Waldeck, Silvia, Kehl, Victoria, Follo, Marie, Philipp, Ulrike, Sauter, Andreas, Specht, Katja, Mitschke, Jan, Lange, Thoralf, Bauer, Sebastian, Jost, Philipp J., Peschel, Christian, Duyster, Justus, Gaiser, Timo, Hohenberger, Peter, Bubnoff, Nikolas
Published in International journal of cancer (15.10.2019)
Published in International journal of cancer (15.10.2019)
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Assessment of droplet digital polymerase chain reaction for measuring BCR‐ABL1 in chronic myeloid leukaemia in an international interlaboratory study
Scott, Stuart, Cartwright, Ashley, Francis, Sebastian, Whitby, Liam, Sanzone, A. Pia, Mulder, André, Galimberti, Sara, Dulucq, Stephanie, Mauté, Carole, Lauricella, Calogero, Salmon, Matthew, Rose, Susan, Willoughby, Josh, Boeckx, Nancy, Pallisgaard, Niels, Maier, Jacqueline, Leibundgut, Elisabeth O., Zizkova, Hana, Ling Goh, Liuh, Duong, Chinh, Tang, Wing F., Ma, Edmond, Shivakumar, Yogesh, Beppu, Lan, Bhagavatula, Prasanthi, Chantry, Andrew
Published in British journal of haematology (01.07.2021)
Published in British journal of haematology (01.07.2021)
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Increasing the Sensitivity of BCR-ABL Monitoring By Digital PCR By Reducing the Background Noise
Franke, Georg-Nikolaus, Maier, Jacqueline, Tzonev, Svilen, Shelton, Dawne Naomi, Cross, Michael, Wildenberger, Kathrin, Niederwieser, Dietger, Lange, Thoralf
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Incidence of Low Level Mutations in Newly Diagnosed CML Patients: A Substudy of the German Tiger Trial
Franke, Georg-Nikolaus, Maier, Jacqueline, Wildenberger, Kathrin, Günther, Christine, Cross, Michael, Ernst, Thomas, Fabisch, Christian, Niederwieser, Dietger, Hochhaus, Andreas, Lange, Thoralf
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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A single digital droplet PCR assay to detect multiple KIT exon 11 mutations in tumor and plasma from patients with gastrointestinal stromal tumors
Boonstra, Pieter A, Ter Elst, Arja, Tibbesma, Marco, Bosman, Lisette J, Mathijssen, Ron, Atrafi, Florence, van Coevorden, Frits, Steeghs, Neeltje, Farag, Sheima, Gelderblom, Hans, van der Graaf, Winette T A, Desar, Ingrid M E, Maier, Jacqueline, Overbosch, Jelle, Suurmeijer, Albert J H, Gietema, Jourik, Schuuring, Ed, Reyners, Anna K L
Published in Oncotarget (02.03.2018)
Published in Oncotarget (02.03.2018)
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A Comparison of Droplet Digital PCR and Quantitative RT-PCR for Low Level BCR-ABL in CML Patients with Molecular Responses
Maier, Jacqueline, Franke, Georg-Nikolaus, Schubert, Karoline, Wildenberger, Kathrin, Cross, Michael, Niederwieser, Dietger, Lange, Thoralf
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Results of the European survey on the assessment of deep molecular response in chronic phase CML patients during tyrosine kinase inhibitor therapy (EUREKA registry)
Möbius, Susanne, Schenk, Thomas, Himsel, Danny, Maier, Jacqueline, Franke, Georg-Nikolaus, Saussele, Susanne, Pott, Christiane, Andrikovics, Hajnalka, Meggyesi, Nora, Machova-Polakova, Katerina, Zizkova, Hana, Jurcek, Tomáš, Mesanovic, Semir, Zadro, Renata, Gottardi, Enrico, Haenig, Jens, Schuld, Peter, Cross, Nicholas C. P., Hochhaus, Andreas, Ernst, Thomas
Published in Journal of cancer research and clinical oncology (01.06.2019)
Published in Journal of cancer research and clinical oncology (01.06.2019)
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Quantification of BCR-ABL by digital PCR in samples with high copy numbers and rates of molecular responses (as defined by EUTOS) compared to those detected with standard quantitative real-time PCR
Franke, Georg-Nikolaus, Maier, Jacqueline, Cross, Michael, Wildenberger, Kathrin, Giles, Francis J., Frank, Oliver, Hochhaus, Andreas, Dietz, Christian, Müller, Martin C., Niederwieser, Dietger, Lange, Thoralf
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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Journal Article
Quantification of BCR-ABL with Digital PCR Results in a Significantly Lower Rate of Deep Molecular Responses When Compared to RT-qPCR in CML Patients Treated in the ENEST1st Trial
Franke, Georg-Nikolaus, Maier, Jacqueline, Wildenberger, Kathrin, Cross, Michael, Frank, Oliver, Giles, Frank, Hochhaus, Andreas, Dietz, Christian T., Müller, Martin C., Niederwieser, Dietger, Lange, Thoralf
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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In Ph+BCR-ABL1P210+ acute lymphoblastic leukemia the e13a2 (B2A2) transcript is prevalent
Baccarani, Michele, Iacobucci, Ilaria, Chiaretti, Sabina, Foà’, Robin, Balasubramanian, Poonkuzhali, Paietta, Elisabeth, Foroni, Letizia, Jeromin, Sabine, Izzo, Barbara, Spinelli, Orietta, Varma, Neelam, Menif, Samia, Terragna, Carolina, Seth, Tulika, Bidet, Audrey, Coriu, Daniel, Lunghi, Francesca, Mayer, Jiri, Scappini, Barbara, Langabeer, Stephen, Maier, Jacqueline, Burt, Emma, Candoni, Anna, Albano, Francesco, Luppi, Mario, Zupan, Irena, Lion, Thomas, Zadro, Renata, di Raimondo, Francesco, Poopak, Behzad, Rege-Cambrin, Giovanna, Annunziata, Mario, Ayala, Ana, Salinas-Viedma, Victor, Ines Prado, Ana, Milner, Benedict, Galimberti, Sara, Janssen, Jeroen, Polli, Valentina, Comba, Lorenzo, Borsellino, Beatrice, Annibali, Ombretta, Crugnola, Monica, Passamonti, Francesco
Published in Leukemia (01.03.2020)
Published in Leukemia (01.03.2020)
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Low Level BCR-ABL Mutations and Response to Treatment: A Substudy of the ENEST1st Trial
Franke, Georg-Nikolaus, Maier, Jacqueline, Schubert, Karoline, Cross, Michael, Leiblein, Sabine, Wildenberger, Kathrin, Giles, Frank, Hochhaus, Andreas, Frank, Oliver, Niederwieser, Dietger, Lange, Thoralf
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Low Level BCR-ABL Mutations Below the Detection Limit of Current Standard Screening Techniques Occur Predominantly in the CD34+ Progenitor Cell Compartment in Chronic Phase CML Patients At Diagnosis. A Substudy of the ENEST1st Trial
Maier, Jacqueline, Schubert, Karoline, Cross, Michael, Leiblein, Sabine, Wildenberger, Kathrin, Giles, Frank, Hochhaus, Andreas, Frank, Oliver, Niederwieser, Dietger, Lange, Thoralf
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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