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Leukocyte-Derived IFN-α/β and Epithelial IFN-λ Constitute a Compartmentalized Mucosal Defense System that Restricts Enteric Virus Infections
Mahlakõiv, Tanel, Hernandez, Pedro, Gronke, Konrad, Diefenbach, Andreas, Staeheli, Peter
Published in PLoS pathogens (01.04.2015)
Published in PLoS pathogens (01.04.2015)
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IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmission
Klinkhammer, Jonas, Schnepf, Daniel, Ye, Liang, Schwaderlapp, Marilena, Gad, Hans Henrik, Hartmann, Rune, Garcin, Dominique, Mahlakõiv, Tanel, Staeheli, Peter
Published in eLife (13.04.2018)
Published in eLife (13.04.2018)
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Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation
Nagashima, Hiroyuki, Mahlakõiv, Tanel, Shih, Han-Yu, Davis, Fred P., Meylan, Francoise, Huang, Yuefeng, Harrison, Oliver J., Yao, Chen, Mikami, Yohei, Urban, Joseph F., Caron, Kathleen M., Belkaid, Yasmine, Kanno, Yuka, Artis, David, O’Shea, John J.
Published in Immunity (Cambridge, Mass.) (15.10.2019)
Published in Immunity (Cambridge, Mass.) (15.10.2019)
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Targeted deletion of the TSLP receptor reveals cellular mechanisms that promote type 2 airway inflammation
Kabata, Hiroki, Flamar, Anne-Laure, Mahlakõiv, Tanel, Moriyama, Saya, Rodewald, Hans-Reimer, Ziegler, Steven F., Artis, David
Published in Mucosal immunology (01.07.2020)
Published in Mucosal immunology (01.07.2020)
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Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity
Flamar, Anne-Laure, Klose, Christoph S.N., Moeller, Jesper B., Mahlakõiv, Tanel, Bessman, Nicholas J., Zhang, Wen, Moriyama, Saya, Stokic-Trtica, Vladislava, Rankin, Lucille C., Putzel, Gregory Garbès, Rodewald, Hans-Reimer, He, Zhengxiang, Chen, Lili, Lira, Sergio A., Karsenty, Gerard, Artis, David
Published in Immunity (Cambridge, Mass.) (14.04.2020)
Published in Immunity (Cambridge, Mass.) (14.04.2020)
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Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces
Tsou, Amy M., Yano, Hiroshi, Parkhurst, Christopher N., Mahlakõiv, Tanel, Chu, Coco, Zhang, Wen, He, Zhengxiang, Jarick, Katja J., Zhong, Connie, Putzel, Gregory G., Hatazaki, Mai, Lorenz, Ivo C., Andrew, David, Balderes, Paul, Klose, Christoph S. N., Lira, Sergio A., Artis, David
Published in Nature (London) (24.11.2022)
Published in Nature (London) (24.11.2022)
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IFN-λ determines the intestinal epithelial antiviral host defense
Pott, Johanna, Mahlakõiv, Tanel, Mordstein, Markus, Duerr, Claudia U., Michiels, Thomas, Stockinger, Silvia, Staeheli, Peter, Hornef, Mathias W., Hiscott, John
Published in Proceedings of the National Academy of Sciences - PNAS (10.05.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (10.05.2011)
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The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation
Klose, Christoph S. N., Mahlakõiv, Tanel, Moeller, Jesper B., Rankin, Lucille C., Flamar, Anne-Laure, Kabata, Hiroki, Monticelli, Laurel A., Moriyama, Saya, Putzel, Gregory Garbès, Rakhilin, Nikolai, Shen, Xiling, Kostenis, Evi, König, Gabriele M., Senda, Takashi, Carpenter, Dustin, Farber, Donna L., Artis, David
Published in Nature (London) (14.09.2017)
Published in Nature (London) (14.09.2017)
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The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation
Wallrapp, Antonia, Riesenfeld, Samantha J., Burkett, Patrick R., Abdulnour, Raja-Elie E., Nyman, Jackson, Dionne, Danielle, Hofree, Matan, Cuoco, Michael S., Rodman, Christopher, Farouq, Daneyal, Haas, Brian J., Tickle, Timothy L., Trombetta, John J., Baral, Pankaj, Klose, Christoph S. N., Mahlakõiv, Tanel, Artis, David, Rozenblatt-Rosen, Orit, Chiu, Isaac M., Levy, Bruce D., Kowalczyk, Monika S., Regev, Aviv, Kuchroo, Vijay K.
Published in Nature (London) (21.09.2017)
Published in Nature (London) (21.09.2017)
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Host microbiota constantly control maturation and function of microglia in the CNS
Erny, Daniel, Hrabě de Angelis, Anna Lena, Jaitin, Diego, Wieghofer, Peter, Staszewski, Ori, David, Eyal, Keren-Shaul, Hadas, Mahlakoiv, Tanel, Jakobshagen, Kristin, Buch, Thorsten, Schwierzeck, Vera, Utermöhlen, Olaf, Chun, Eunyoung, Garrett, Wendy S, McCoy, Kathy D, Diefenbach, Andreas, Staeheli, Peter, Stecher, Bärbel, Amit, Ido, Prinz, Marco
Published in Nature neuroscience (01.07.2015)
Published in Nature neuroscience (01.07.2015)
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Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection
Hernández, Pedro P, Mahlakõiv, Tanel, Yang, Ines, Schwierzeck, Vera, Nguyen, Nam, Guendel, Fabian, Gronke, Konrad, Ryffel, Bernhard, Hölscher, Christoph, Dumoutier, Laure, Renauld, Jean-Christophe, Suerbaum, Sebastian, Staeheli, Peter, Diefenbach, Andreas
Published in Nature immunology (01.07.2015)
Published in Nature immunology (01.07.2015)
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Type I and Type III Interferons Drive Redundant Amplification Loops to Induce a Transcriptional Signature in Influenza-Infected Airway Epithelia
Crotta, Stefania, Davidson, Sophia, Mahlakoiv, Tanel, Desmet, Christophe J., Buckwalter, Matthew R., Albert, Matthew L., Staeheli, Peter, Wack, Andreas
Published in PLoS pathogens (01.11.2013)
Published in PLoS pathogens (01.11.2013)
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Human but Not Mouse Hepatocytes Respond to Interferon-Lambda In Vivo
Hermant, Pascale, Demarez, Céline, Mahlakõiv, Tanel, Staeheli, Peter, Meuleman, Philip, Michiels, Thomas
Published in PloS one (31.01.2014)
Published in PloS one (31.01.2014)
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Identification of Continuous Human B-Cell Epitopes in the VP35, VP40, Nucleoprotein and Glycoprotein of Ebola Virus
Becquart, Pierre, Mahlakõiv, Tanel, Nkoghe, Dieudonné, Leroy, Eric M.
Published in PloS one (10.06.2014)
Published in PloS one (10.06.2014)
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Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance
Swamy, Mahima, Abeler-Dörner, Lucie, Chettle, James, Mahlakõiv, Tanel, Goubau, Delphine, Chakravarty, Probir, Ramsay, George, Reis e Sousa, Caetano, Staeheli, Peter, Blacklaws, Barbara A., Heeney, Jonathan L., Hayday, Adrian C.
Published in Nature communications (19.05.2015)
Published in Nature communications (19.05.2015)
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Activation of Type III Interferon Genes by Pathogenic Bacteria in Infected Epithelial Cells and Mouse Placenta
Bierne, Hélène, Travier, Laetitia, Mahlakõiv, Tanel, Tailleux, Ludovic, Subtil, Agathe, Lebreton, Alice, Paliwal, Anupam, Gicquel, Brigitte, Staeheli, Peter, Lecuit, Marc, Cossart, Pascale
Published in PloS one (14.06.2012)
Published in PloS one (14.06.2012)
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Correction: High Prevalence of Both Humoral and Cellular Immunity to Zaire ebolavirus among Rural Populations in Gabon
Becquart, Pierre, Wauquier, Nadia, Mahlakõiv, Tanel, Nkoghe, Dieudonné, Padilla, Cindy, Souris, Marc, Ollomo, Benjamin, Gonzalez, Jean-Paul, De Lamballerie, Xavier, Kazanji, Mirdad, Leroy, Eric M.
Published in PloS one (26.02.2010)
Published in PloS one (26.02.2010)
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Rotavirus susceptibility of antibiotic-treated mice ascribed to diminished expression of interleukin-22
Schnepf, Daniel, Hernandez, Pedro, Mahlakõiv, Tanel, Crotta, Stefania, Sullender, Meagan E., Peterson, Stefan T., Ohnemus, Annette, Michiels, Camille, Gentle, Ian, Dumoutier, Laure, Reis, Celso A., Diefenbach, Andreas, Wack, Andreas, Baldridge, Megan T., Staeheli, Peter
Published in PloS one (12.08.2021)
Published in PloS one (12.08.2021)
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