ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer
Mahajan, Kiran, Malla, Pavani, Lawrence, Harshani R., Chen, Zhihua, Kumar-Sinha, Chandan, Malik, Rohit, Shukla, Sudhanshu, Kim, Jongphil, Coppola, Domenico, Lawrence, Nicholas J., Mahajan, Nupam P.
Published in Cancer cell (12.06.2017)
Published in Cancer cell (12.06.2017)
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Loss of Long Noncoding RNA NXTAR in Prostate Cancer Augments Androgen Receptor Expression and Enzalutamide Resistance
Ghildiyal, Ruchi, Sawant, Mithila, Renganathan, Arun, Mahajan, Kiran, Kim, Eric H, Luo, Jingqin, Dang, Ha X, Maher, Christopher A, Feng, Felix Y, Mahajan, Nupam P
Published in Cancer research (Chicago, Ill.) (01.01.2022)
Published in Cancer research (Chicago, Ill.) (01.01.2022)
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H2B Tyr37 phosphorylation suppresses expression of replication-dependent core histone genes
Mahajan, Kiran, Fang, Bin, Koomen, John M, Mahajan, Nupam P
Published in Nature structural & molecular biology (01.09.2012)
Published in Nature structural & molecular biology (01.09.2012)
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Histone H2A Lys130 acetylation epigenetically regulates androgen production in prostate cancer
Nguyen, Thanh, Sridaran, Dhivya, Chouhan, Surbhi, Weimholt, Cody, Wilson, Audrey, Luo, Jingqin, Li, Tiandao, Koomen, John, Fang, Bin, Putluri, Nagireddy, Sreekumar, Arun, Feng, Felix Y., Mahajan, Kiran, Mahajan, Nupam P.
Published in Nature communications (09.06.2023)
Published in Nature communications (09.06.2023)
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Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase counteracts prostate cancer immune checkpoint blockade resistance
Sridaran, Dhivya, Chouhan, Surbhi, Mahajan, Kiran, Renganathan, Arun, Weimholt, Cody, Bhagwat, Shambhavi, Reimers, Melissa, Kim, Eric H., Thakur, Manish K., Saeed, Muhammad A., Pachynski, Russell K., Seeliger, Markus A., Miller, W. Todd, Feng, Felix Y., Mahajan, Nupam P.
Published in Nature communications (14.11.2022)
Published in Nature communications (14.11.2022)
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TNK2/ACK1-mediated phosphorylation of ATP5F1A (ATP synthase F1 subunit alpha) selectively augments survival of prostate cancer while engendering mitochondrial vulnerability
Chouhan, Surbhi, Sawant, Mithila, Weimholt, Cody, Luo, Jingqin, Sprung, Robert W., Terrado, Mailyn, Mueller, David M., Earp, H. Shelton, Mahajan, Nupam P.
Published in Autophagy (04.03.2023)
Published in Autophagy (04.03.2023)
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Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation
Mahajan, Kiran, Coppola, Domenico, Challa, Sridevi, Fang, Bin, Chen, Y Ann, Zhu, Weiwei, Lopez, Alexis S, Koomen, John, Engelman, Robert W, Rivera, Charlene, Muraoka-Cook, Rebecca S, Cheng, Jin Q, Schönbrunn, Ernst, Sebti, Said M, Earp, H Shelton, Mahajan, Nupam P
Published in PloS one (19.03.2010)
Published in PloS one (19.03.2010)
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Author Correction: Histone H2A Lys130 acetylation epigenetically regulates androgen production in prostate cancer
Nguyen, Thanh, Sridaran, Dhivya, Chouhan, Surbhi, Weimholt, Cody, Wilson, Audrey, Luo, Jingqin, Li, Tiandao, Koomen, John, Fang, Bin, Putluri, Nagireddy, Sreekumar, Arun, Feng, Felix Y., Mahajan, Kiran, Mahajan, Nupam P.
Published in Nature communications (27.09.2023)
Published in Nature communications (27.09.2023)
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Epigenetic underpinnings of tumor-immune dynamics in prostate cancer immune suppression
Angappulige, Duminduni Hewa, Mahajan, Nupam P, Mahajan, Kiran
Published in Trends in cancer (01.04.2024)
Published in Trends in cancer (01.04.2024)
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SHP2 as a primordial epigenetic enzyme expunges histone H3 pTyr-54 to amend androgen receptor homeostasis
Chouhan, Surbhi, Sridaran, Dhivya, Weimholt, Cody, Luo, Jingqin, Li, Tiandao, Hodgson, Myles C., Santos, Luana N., Le Sommer, Samantha, Fang, Bin, Koomen, John M., Seeliger, Markus, Qu, Cheng-Kui, Yart, Armelle, Kontaridis, Maria I., Mahajan, Kiran, Mahajan, Nupam P.
Published in Nature communications (04.07.2024)
Published in Nature communications (04.07.2024)
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Prostate cancer immunotherapy: Improving clinical outcomes with a multi-pronged approach
Sridaran, Dhivya, Bradshaw, Elliot, DeSelm, Carl, Pachynski, Russell, Mahajan, Kiran, Mahajan, Nupam P.
Published in Cell reports. Medicine (17.10.2023)
Published in Cell reports. Medicine (17.10.2023)
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Epigenetic reprogramming of cell cycle genes by ACK1 promotes breast cancer resistance to CDK4/6 inhibitor
Sawant, Mithila, Wilson, Audrey, Sridaran, Dhivya, Mahajan, Kiran, O’Conor, Christopher J., Hagemann, Ian S., Luo, Jingqin, Weimholt, Cody, Li, Tiandao, Roa, Juan Carlos, Pandey, Akhilesh, Wu, Xinyan, Mahajan, Nupam P.
Published in Oncogene (14.07.2023)
Published in Oncogene (14.07.2023)
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Acetylated HOXB13 Regulated Super Enhancer Genes Define Therapeutic Vulnerabilities of Castration-Resistant Prostate Cancer
Nguyen, Duy T, Yang, Wei, Renganathan, Arun, Weimholt, Cody, Angappulige, Duminduni H, Nguyen, Thanh, Sprung, Robert W, Andriole, Gerald L, Kim, Eric H, Mahajan, Nupam P, Mahajan, Kiran
Published in Clinical cancer research (15.09.2022)
Published in Clinical cancer research (15.09.2022)
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Inhibition of ACK1 delays and overcomes acquired resistance of EGFR mutant NSCLC cells to the third generation EGFR inhibitor, osimertinib
Gu, Jiajia, Qian, Luxi, Zhang, Guojing, Mahajan, Nupam P., Owonikoko, Taofeek K., Ramalingam, Suresh S., Sun, Shi-Yong
Published in Lung cancer (Amsterdam, Netherlands) (01.12.2020)
Published in Lung cancer (Amsterdam, Netherlands) (01.12.2020)
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