Advances in therapeutic peptides targeting G protein-coupled receptors
Davenport, Anthony P., Scully, Conor C. G., de Graaf, Chris, Brown, Alastair J. H., Maguire, Janet J.
Published in Nature reviews. Drug discovery (01.06.2020)
Published in Nature reviews. Drug discovery (01.06.2020)
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Journal Article
Intracellular Interleukin-1 Receptor 2 Binding Prevents Cleavage and Activity of Interleukin-1α, Controlling Necrosis-Induced Sterile Inflammation
Zheng, Yue, Humphry, Melanie, Maguire, Janet J., Bennett, Martin R., Clarke, Murray C.H.
Published in Immunity (Cambridge, Mass.) (21.02.2013)
Published in Immunity (Cambridge, Mass.) (21.02.2013)
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Journal Article
Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension
Yang, Peiran, Read, Cai, Kuc, Rhoda E, Buonincontri, Guido, Southwood, Mark, Torella, Rubben, Upton, Paul D, Crosby, Alexi, Sawiak, Stephen J, Carpenter, T Adrian, Glen, Robert C, Morrell, Nicholas W, Maguire, Janet J, Davenport, Anthony P
Published in Circulation (New York, N.Y.) (21.03.2017)
Published in Circulation (New York, N.Y.) (21.03.2017)
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Journal Article
Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction
Ford, Thomas J, Corcoran, David, Padmanabhan, Sandosh, Aman, Alisha, Rocchiccioli, Paul, Good, Richard, McEntegart, Margaret, Maguire, Janet J, Watkins, Stuart, Eteiba, Hany, Shaukat, Aadil, Lindsay, Mitchell, Robertson, Keith, Hood, Stuart, McGeoch, Ross, McDade, Robert, Yii, Eric, Sattar, Naveed, Hsu, Li-Yueh, Arai, Andrew E, Oldroyd, Keith G, Touyz, Rhian M, Davenport, Anthony P, Berry, Colin
Published in European heart journal (07.09.2020)
Published in European heart journal (07.09.2020)
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Journal Article
Design, Characterization, and First-In-Human Study of the Vascular Actions of a Novel Biased Apelin Receptor Agonist
Brame, Aimee L, Maguire, Janet J, Yang, Peiran, Dyson, Alex, Torella, Rubben, Cheriyan, Joseph, Singer, Mervyn, Glen, Robert C, Wilkinson, Ian B, Davenport, Anthony P
Published in Hypertension (Dallas, Tex. 1979) (01.04.2015)
Published in Hypertension (Dallas, Tex. 1979) (01.04.2015)
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Journal Article
The therapeutic potential of apelin in kidney disease
Chapman, Fiona A., Nyimanu, Duuamene, Maguire, Janet J., Davenport, Anthony P., Newby, David E., Dhaun, Neeraj
Published in Nature reviews. Nephrology (01.12.2021)
Published in Nature reviews. Nephrology (01.12.2021)
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Journal Article
Cardiovascular and renal effects of apelin in chronic kidney disease: a randomised, double-blind, placebo-controlled, crossover study
Chapman, Fiona A., Melville, Vanessa, Godden, Emily, Morrison, Beth, Bruce, Lorraine, Maguire, Janet J., Davenport, Anthony P., Newby, David E., Dhaun, Neeraj
Published in Nature communications (14.10.2024)
Published in Nature communications (14.10.2024)
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Journal Article
Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis
Bennett, Martin R, Clarke, Murray C H, Figg, Nichola, Maguire, Janet J, Davenport, Anthony P, Goddard, Martin, Littlewood, Trevor D
Published in Nature medicine (01.09.2006)
Published in Nature medicine (01.09.2006)
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Journal Article
Chronic Apoptosis of Vascular Smooth Muscle Cells Accelerates Atherosclerosis and Promotes Calcification and Medial Degeneration
Clarke, Murray C.H, Littlewood, Trevor D, Figg, Nichola, Maguire, Janet J, Davenport, Anthony P, Goddard, Martin, Bennett, Martin R
Published in Circulation research (20.06.2008)
Published in Circulation research (20.06.2008)
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Journal Article
Differential expression in humans of the viral entry receptor ACE2 compared with the short deltaACE2 isoform lacking SARS-CoV-2 binding sites
Williams, Thomas L., Strachan, Gregory, Macrae, Robyn G. C., Kuc, Rhoda E., Nyimanu, Duuamene, Paterson, Anna L., Sinha, Sanjay, Maguire, Janet J., Davenport, Anthony P.
Published in Scientific reports (21.12.2021)
Published in Scientific reports (21.12.2021)
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Journal Article
Expression of the apelin receptor, a novel potential therapeutic target, and its endogenous ligands in diverse stem cell populations in human glioblastoma
Williams, Thomas L, Nwokoye, Peter, Kuc, Rhoda E, Smith, Kieran, Paterson, Anna L, Allinson, Kieren, Maguire, Janet J, Davenport, Anthony P
Published in Frontiers in neuroscience (13.05.2024)
Published in Frontiers in neuroscience (13.05.2024)
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Journal Article
The biased apelin receptor agonist, MM07, reverses Sugen/hypoxia-induced pulmonary arterial hypertension as effectively as the endothelin antagonist macitentan
Williams, Thomas L, Nyimanu, Duuamene, Kuc, Rhoda E, Foster, Richard, Glen, Robert C, Maguire, Janet J, Davenport, Anthony P
Published in Frontiers in pharmacology (09.04.2024)
Published in Frontiers in pharmacology (09.04.2024)
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Journal Article
Modulation of the apelin/APJ system in heart failure and atherosclerosis in man
Pitkin, Sarah L, Maguire, Janet J, Kuc, Rhoda E, Davenport, Anthony P
Published in British journal of pharmacology (01.08.2010)
Published in British journal of pharmacology (01.08.2010)
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Journal Article
Chemerin Elicits Potent Constrictor Actions via Chemokine‐Like Receptor 1 (CMKLR1), not G‐Protein‐Coupled Receptor 1 (GPR1), in Human and Rat Vasculature
Kennedy, Amanda J., Yang, Peiran, Read, Cai, Kuc, Rhoda E., Yang, Lucy, Taylor, Emily J. A., Taylor, Colin W., Maguire, Janet J., Davenport, Anthony P.
Published in Journal of the American Heart Association (01.10.2016)
Published in Journal of the American Heart Association (01.10.2016)
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