Advances in therapeutic peptides targeting G protein-coupled receptors
Davenport, Anthony P., Scully, Conor C. G., de Graaf, Chris, Brown, Alastair J. H., Maguire, Janet J.
Published in Nature reviews. Drug discovery (01.06.2020)
Published in Nature reviews. Drug discovery (01.06.2020)
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Journal Article
Intracellular Interleukin-1 Receptor 2 Binding Prevents Cleavage and Activity of Interleukin-1α, Controlling Necrosis-Induced Sterile Inflammation
Zheng, Yue, Humphry, Melanie, Maguire, Janet J., Bennett, Martin R., Clarke, Murray C.H.
Published in Immunity (Cambridge, Mass.) (21.02.2013)
Published in Immunity (Cambridge, Mass.) (21.02.2013)
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Journal Article
Endothelin
Davenport, Anthony P, Hyndman, Kelly A, Dhaun, Neeraj, Southan, Christopher, Kohan, Donald E, Pollock, Jennifer S, Pollock, David M, Webb, David J, Maguire, Janet J
Published in Pharmacological reviews (01.04.2016)
Published in Pharmacological reviews (01.04.2016)
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Journal Article
Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension
Yang, Peiran, Read, Cai, Kuc, Rhoda E, Buonincontri, Guido, Southwood, Mark, Torella, Rubben, Upton, Paul D, Crosby, Alexi, Sawiak, Stephen J, Carpenter, T Adrian, Glen, Robert C, Morrell, Nicholas W, Maguire, Janet J, Davenport, Anthony P
Published in Circulation (New York, N.Y.) (21.03.2017)
Published in Circulation (New York, N.Y.) (21.03.2017)
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Journal Article
Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction
Ford, Thomas J, Corcoran, David, Padmanabhan, Sandosh, Aman, Alisha, Rocchiccioli, Paul, Good, Richard, McEntegart, Margaret, Maguire, Janet J, Watkins, Stuart, Eteiba, Hany, Shaukat, Aadil, Lindsay, Mitchell, Robertson, Keith, Hood, Stuart, McGeoch, Ross, McDade, Robert, Yii, Eric, Sattar, Naveed, Hsu, Li-Yueh, Arai, Andrew E, Oldroyd, Keith G, Touyz, Rhian M, Davenport, Anthony P, Berry, Colin
Published in European heart journal (07.09.2020)
Published in European heart journal (07.09.2020)
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Journal Article
Targeting the apelin system for the treatment of cardiovascular diseases
Chapman, Fiona A, Maguire, Janet J, Newby, David E, Davenport, Anthony P, Dhaun, Neeraj
Published in Cardiovascular research (30.12.2023)
Published in Cardiovascular research (30.12.2023)
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Journal Article
The therapeutic potential of apelin in kidney disease
Chapman, Fiona A., Nyimanu, Duuamene, Maguire, Janet J., Davenport, Anthony P., Newby, David E., Dhaun, Neeraj
Published in Nature reviews. Nephrology (01.12.2021)
Published in Nature reviews. Nephrology (01.12.2021)
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Journal Article
Design, Characterization, and First-In-Human Study of the Vascular Actions of a Novel Biased Apelin Receptor Agonist
Brame, Aimee L, Maguire, Janet J, Yang, Peiran, Dyson, Alex, Torella, Rubben, Cheriyan, Joseph, Singer, Mervyn, Glen, Robert C, Wilkinson, Ian B, Davenport, Anthony P
Published in Hypertension (Dallas, Tex. 1979) (01.04.2015)
Published in Hypertension (Dallas, Tex. 1979) (01.04.2015)
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Journal Article
International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand
Read, Cai, Nyimanu, Duuamene, Williams, Thomas L, Huggins, David J, Sulentic, Petra, Macrae, Robyn G C, Yang, Peiran, Glen, Robert C, Maguire, Janet J, Davenport, Anthony P
Published in Pharmacological reviews (01.10.2019)
Published in Pharmacological reviews (01.10.2019)
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Journal Article
Cardiovascular and renal effects of apelin in chronic kidney disease: a randomised, double-blind, placebo-controlled, crossover study
Chapman, Fiona A., Melville, Vanessa, Godden, Emily, Morrison, Beth, Bruce, Lorraine, Maguire, Janet J., Davenport, Anthony P., Newby, David E., Dhaun, Neeraj
Published in Nature communications (14.10.2024)
Published in Nature communications (14.10.2024)
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Journal Article
A rational roadmap for SARS‐CoV‐2/COVID‐19 pharmacotherapeutic research and development: IUPHAR Review 29
Alexander, Steve P.H., Armstrong, Jane F., Davenport, Anthony P., Davies, Jamie A., Faccenda, Elena, Harding, Simon D., Levi‐Schaffer, Francesca, Maguire, Janet J., Pawson, Adam J., Southan, Christopher, Spedding, Michael
Published in British journal of pharmacology (01.11.2020)
Published in British journal of pharmacology (01.11.2020)
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Journal Article
Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis
Bennett, Martin R, Clarke, Murray C H, Figg, Nichola, Maguire, Janet J, Davenport, Anthony P, Goddard, Martin, Littlewood, Trevor D
Published in Nature medicine (01.09.2006)
Published in Nature medicine (01.09.2006)
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Journal Article
Chronic Apoptosis of Vascular Smooth Muscle Cells Accelerates Atherosclerosis and Promotes Calcification and Medial Degeneration
Clarke, Murray C.H, Littlewood, Trevor D, Figg, Nichola, Maguire, Janet J, Davenport, Anthony P, Goddard, Martin, Bennett, Martin R
Published in Circulation research (20.06.2008)
Published in Circulation research (20.06.2008)
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Journal Article
Endothelin-1 is increased in the plasma of patients hospitalised with Covid-19
Abraham, George R., Kuc, Rhoda E., Althage, Magnus, Greasley, Peter J., Ambery, Philip, Maguire, Janet J., Wilkinson, Ian B., Hoole, Stephen P., Cheriyan, Joseph, Davenport, Anthony P.
Published in Journal of molecular and cellular cardiology (01.06.2022)
Published in Journal of molecular and cellular cardiology (01.06.2022)
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Journal Article
Differential expression in humans of the viral entry receptor ACE2 compared with the short deltaACE2 isoform lacking SARS-CoV-2 binding sites
Williams, Thomas L., Strachan, Gregory, Macrae, Robyn G. C., Kuc, Rhoda E., Nyimanu, Duuamene, Paterson, Anna L., Sinha, Sanjay, Maguire, Janet J., Davenport, Anthony P.
Published in Scientific reports (21.12.2021)
Published in Scientific reports (21.12.2021)
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