Preclinical and phase I clinical studies of KW-2450, a dual IGF-1R/IR tyrosine kinase inhibitor, in combination with lapatinib and letrozole
Umehara, Hiroshi, Maekawa, Yoshimi, Koizumi, Fumito, Shimizu, Makiko, Ota, Toshio, Fouad, Tamer M., Willey, Jie, Kaito, Hidekuni, Shiraishi, Norihiko, Nakashima, Daisuke, Akinaga, Shiro, Ueno, Naoto T.
Published in Therapeutic advances in medical oncology (01.01.2018)
Published in Therapeutic advances in medical oncology (01.01.2018)
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Predicting 5-FU sensitivity using human colorectal cancer specimens: comparison of tumor dihydropyrimidine dehydrogenase and orotate phosphoribosyl transferase activities with in vitro chemosensitivity to 5-FU
Isshi, Kimio, Sakuyama, Toshikazu, Gen, Tomoyasu, Nakamura, Yasuyuki, Kuroda, Toru, Katuyama, Toshiyuki, Maekawa, Yoshimi
Published in International journal of clinical oncology (01.12.2002)
Published in International journal of clinical oncology (01.12.2002)
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A Neutralizing Anti–Fibroblast Growth Factor 8 Monoclonal Antibody Shows Potent Antitumor Activity against Androgen-Dependent Mouse Mammary Tumors In vivo
Shimada, Naoki, Ishii, Toshihiko, Imada, Teruyoshi, Takaba, Katsumi, Sasaki, Yuka, Maruyama-Takahashi, Kumiko, Maekawa-Tokuda, Yoshimi, Kusaka, Hideaki, Akinaga, Shiro, Tanaka, Akira, Shitara, Kenya
Published in Clinical cancer research (15.05.2005)
Published in Clinical cancer research (15.05.2005)
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A neutralizing anti-fibroblast growth factor (FGF) 8 monoclonal antibody shows anti-tumor activity against FGF8b-expressing LNCaP xenografts in androgen-dependent and -independent conditions
Maruyama-Takahashi, Kumiko, Shimada, Naoki, Imada, Teruyoshi, Maekawa-Tokuda, Yoshimi, Ishii, Toshihiko, Ouchi, Jun, Kusaka, Hideaki, Miyaji, Hiromasa, Akinaga, Shiro, Tanaka, Akira, Shitara, Kenya
Published in The Prostate (01.05.2008)
Published in The Prostate (01.05.2008)
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Preclinical and first‐in‐human phase I studies of KW‐2450, an oral tyrosine kinase inhibitor with insulin‐like growth factor receptor‐1/insulin receptor selectivity
Schwartz, Gary K., Dickson, Mark A., LoRusso, Patricia M., Sausville, Edward A., Maekawa, Yoshimi, Watanabe, Yasuo, Kashima, Naomi, Nakashima, Daisuke, Akinaga, Shiro
Published in Cancer science (01.04.2016)
Published in Cancer science (01.04.2016)
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First Preclinical Report of the Efficacy and PD Results of KHK2823, a Non-Fucosylated Fully Human Monoclonal Antibody Against IL-3Rα
Akiyama, Tadakazu, Takayanagi, Shin-ichiro, Maekawa, Yoshimi, Miyawaki, Kohta, Jinnouchi, Fumiaki, Jiromaru, Takashi, Sugio, Takeshi, Daitoku, Shinya, Kusumoto, Hirotake, Shimabe, Munetake, Nishikawa, Satoshi, Yamawaki, Kengo, Iijima, Kousuke, Hiura, Masanori, Takahashi, Takeshi, Kikushige, Yoshikane, Iwasaki, Hiromi, Akashi, Koichi, Tawara, Tomonori
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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TACHIBANA MASANORI, MAEKAWA YOSHIMI, FUKUNAGA NAOMI, UMEMATSU MIMIO, SHIMAZAKI AKIRA, HIRANO YUKIHIRO
Year of Publication 28.02.2019
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Year of Publication 28.02.2019
Patent
Abstract 920: KW-2450, a novel IGF-1R/IR inhibitor, enhances the antitumor effect of lapatinib, letrozole or 4-hydroxy-tamoxifen in breast cancer cells
Umehara, Hiroshi, Koizumi, Fumito, Maekawa, Yoshimi, Shimizu, Makiko, Nakamura, Hiroaki, Ota, Toshio, Nara, Shinji, Takahashi, Takeshi, Kanda, Yutaka, Shiraishi, Norihiko, Akinaga, Shiro, Shiotsu, Yukimasa, Soga, Shiro
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Abstract 3605: KW-2450, a novel orally-active dual IGF1R/IR inhibitor: Antitumor effects in vitro and in vivo
Maekawa, Yoshimi, Koizumi, Fumito, Kashima, Naomi, Suzuki, Masayo, Umehara, Hiroshi, Takahashi, Hiroko, Nakamura, Hiroaki, Nara, Shinji, Nakazato, Tomoyuki, Kanda, Yutaka, Takahashi, Takeshi, Akinaga, Shiro, Shiotsu, Yukimasa, Soga, Shiro
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Information processing apparatus
Maekawa, Yoshimi, Umematsu, Misao, Tachibana, Masanori, Shimasaki, Akira, Fukunaga, Naomi, Hirano, Yukihiro
Year of Publication 23.07.2019
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Year of Publication 23.07.2019
Patent
INFORMATION PROCESSING APPARATUS
Maekawa, Yoshimi, Umematsu, Misao, Tachibana, Masanori, Shimasaki, Akira, Fukunaga, Naomi, Hirano, Yukihiro
Year of Publication 07.02.2019
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Year of Publication 07.02.2019
Patent
A Neutralizing Anti-Fibroblast Growth Factor (FGF) 8 Monoclonal Antibody Shows Anti-Tumor Activity Against FGF8b-Expressing LNCaPXenografts in Androgen-Dependent and -Independent Conditions
MARUYAMA-TAKAHASHI, Kumiko, SHIMADA, Naoki, SHITARA, Kenya, IMADA, Teruyoshi, MAEKAWA-TOKUDA, Yoshimi, ISHII, Toshihiko, OUCHI, Jun, KUSAKA, Hideaki, MIYAJI, Hiromasa, AKINAGA, Shiro, TANAKA, Akira
Published in The Prostate (2008)
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Published in The Prostate (2008)
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