Nrf2 Expression Is Decreased in LRRK2 Transgenic Mouse Brain and LRRK2 Overexpressing SH-SY5Y Cells
Kawakami, Fumitaka, Imai, Motoki, Tamaki, Shun, Ohta, Etsuro, Kawashima, Rei, Maekawa, Tatsunori, Kurosaki, Yoshifumi, Ohba, Kenichi, Ichikawa, Takafumi
Published in Biological & pharmaceutical bulletin (01.01.2023)
Published in Biological & pharmaceutical bulletin (01.01.2023)
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Journal Article
Interleukin-13 Mediates Non-Steroidal Anti-Inflammatory-Drug-Induced Small Intestinal Mucosal Injury with Ulceration
Kawashima, Rei, Tamaki, Shun, Hara, Yusuke, Maekawa, Tatsunori, Kawakami, Fumitaka, Ichikawa, Takafumi
Published in International journal of molecular sciences (01.10.2023)
Published in International journal of molecular sciences (01.10.2023)
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Journal Article
LRRK2 Inhibition Ameliorates Dexamethasone-Induced Glucose Intolerance via Prevents Impairment in GLUT4 Membrane Translocation in Adipocytes
Imai, Motoki, Kawakami, Fumitaka, Kubo, Makoto, Kanzaki, Makoto, Maruyama, Hiroko, Kawashima, Rei, Maekawa, Tatsunori, Kurosaki, Yoshifumi, Kojima, Fumiaki, Ichikawa, Takafumi
Published in Biological & pharmaceutical bulletin (01.11.2020)
Published in Biological & pharmaceutical bulletin (01.11.2020)
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Journal Article
LRRK2 phosphorylates tubulin-associated tau but not the free molecule: LRRK2-mediated regulation of the tau-tubulin association and neurite outgrowth
Kawakami, Fumitaka, Yabata, Takatoshi, Ohta, Etsuro, Maekawa, Tatsunori, Shimada, Naoki, Suzuki, Minori, Maruyama, Hiroko, Ichikawa, Takafumi, Obata, Fumiya
Published in PloS one (27.01.2012)
Published in PloS one (27.01.2012)
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Journal Article
Leucine-Rich Repeat Kinase 2 Controls Inflammatory Cytokines Production through NF-κB Phosphorylation and Antigen Presentation in Bone Marrow-Derived Dendritic Cells
Kubo, Makoto, Nagashima, Ryuichi, Kurihara, Mitsue, Kawakami, Fumitaka, Maekawa, Tatsunori, Eshima, Koji, Ohta, Etsuro, Kato, Hirotomo, Obata, Fumiya
Published in International journal of molecular sciences (10.03.2020)
Published in International journal of molecular sciences (10.03.2020)
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Journal Article
Leucine-Rich Repeat Kinase 2 Is Associated With Activation of the Paraventricular Nucleus of the Hypothalamus and Stress-Related Gastrointestinal Dysmotility
Maekawa, Tatsunori, Tsushima, Hiromichi, Kawakami, Fumitaka, Kawashima, Rei, Kodo, Masaru, Imai, Motoki, Ichikawa, Takafumi
Published in Frontiers in neuroscience (29.08.2019)
Published in Frontiers in neuroscience (29.08.2019)
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Journal Article
LRRK2 negatively regulates glucose tolerance via regulation of membrane translocation of GLUT4 in adipocytes
Kawakami, Fumitaka, Imai, Motoki, Isaka, Yuki, Cookson, Mark R., Maruyama, Hiroko, Kubo, Makoto, Farrer, Matthew J., Kanzaki, Makoto, Kawashima, Rei, Maekawa, Tatsunori, Tamaki, Shun, Kurosaki, Yoshifumi, Kojima, Fumiaki, Ohba, Kenichi, Ichikawa, Takafumi
Published in FEBS open bio (01.12.2023)
Published in FEBS open bio (01.12.2023)
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Journal Article
Leucine-rich repeat kinase 2 is a regulator of B cell function, affecting homeostasis, BCR signaling, IgA production, and TI antigen responses
Kubo, Makoto, Nagashima, Ryuichi, Ohta, Etsuro, Maekawa, Tatsunori, Isobe, Yumiko, Kurihara, Mitsue, Eshima, Koji, Iwabuchi, Kazuya, Sasaoka, Toshikuni, Azuma, Sadahiro, Melrose, Heather L, Farrer, Matthew J, Obata, Fumiya
Published in Journal of neuroimmunology (15.03.2016)
Published in Journal of neuroimmunology (15.03.2016)
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Journal Article
The I2020T Leucine-rich repeat kinase 2 transgenic mouse exhibits impaired locomotive ability accompanied by dopaminergic neuron abnormalities
Maekawa, Tatsunori, Mori, Sayuri, Sasaki, Yui, Miyajima, Takashi, Azuma, Sadahiro, Ohta, Etsuro, Obata, Fumiya
Published in Molecular neurodegeneration (25.04.2012)
Published in Molecular neurodegeneration (25.04.2012)
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Journal Article
I2020T leucine-rich repeat kinase 2, the causative mutant molecule of familial Parkinson’s disease, has a higher intracellular degradation rate than the wild-type molecule
Ohta, Etsuro, Katayama, Yuri, Kawakami, Fumitaka, Yamamoto, Matsuri, Tajima, Kana, Maekawa, Tatsunori, Iida, Naoyuki, Hattori, Seisuke, Obata, Fumiya
Published in Biochemical and biophysical research communications (01.12.2009)
Published in Biochemical and biophysical research communications (01.12.2009)
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Journal Article
Biphenotypic Cells and α-Synuclein Accumulation in Enteric Neurons of Leucine-Rich Repeat Kinase 2 Knockout Mice
Maekawa, Tatsunori, Motokawa, Ryuichi, Kawashima, Rei, Tamaki, Shun, Hara, Yusuke, Kawakami, Fumitaka, Ichikawa, Takafumi
Published in Digestive diseases and sciences (01.08.2024)
Published in Digestive diseases and sciences (01.08.2024)
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Journal Article
Leucine‐rich repeat kinase 2 regulates tau phosphorylation through direct activation of glycogen synthase kinase‐3β
Kawakami, Fumitaka, Shimada, Naoki, Ohta, Etsuro, Kagiya, Go, Kawashima, Rei, Maekawa, Tatsunori, Maruyama, Hiroko, Ichikawa, Takafumi
Published in The FEBS journal (01.01.2014)
Published in The FEBS journal (01.01.2014)
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Journal Article
LRRK2: An Emerging New Molecule in the Enteric Neuronal System That Quantitatively Regulates Neuronal Peptides and IgA in the Gut
Maekawa, Tatsunori, Shimayama, Hitomi, Tsushima, Hiromichi, Kawakami, Fumitaka, Kawashima, Rei, Kubo, Makoto, Ichikawa, Takafumi
Published in Digestive diseases and sciences (01.04.2017)
Published in Digestive diseases and sciences (01.04.2017)
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Journal Article
Elemental diet moderates 5-fluorouracil-induced gastrointestinal mucositis through mucus barrier alteration
Kawashima, Rei, Kawakami, Fumitaka, Maekawa, Tatsunori, Yamamoto, Hajime, Koizumi, Wasaburo, Ichikawa, Takafumi
Published in Cancer chemotherapy and pharmacology (01.08.2015)
Published in Cancer chemotherapy and pharmacology (01.08.2015)
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Journal Article
LRRK2 is expressed in B-2 but not in B-1 B cells, and downregulated by cellular activation
Kubo, Makoto, Kamiya, Yoshiko, Nagashima, Ryuichi, Maekawa, Tatsunori, Eshima, Koji, Azuma, Sadahiro, Ohta, Etsuro, Obata, Fumiya
Published in Journal of neuroimmunology (15.12.2010)
Published in Journal of neuroimmunology (15.12.2010)
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Journal Article
Tu1242 Changes in the Mucus Barrier Are the “Causes” or “Results” of Chemotherapy-Induced Mucositis?
Ichikawa, Takafumi, Yamamoto, Hajime, Kawakami, Fumitaka, Kawashima, Rei, Maekawa, Tatsunori, Koizumi, Wasaburo
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2014)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2014)
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Journal Article