Discovery and Characterization of 2,5-Substituted Benzoic Acid Dual Inhibitors of the Anti-apoptotic Mcl‑1 and Bfl‑1 Proteins
Kump, Karson J, Miao, Lei, Mady, Ahmed S. A, Ansari, Nurul H, Shrestha, Uttar K, Yang, Yuting, Pal, Mohan, Liao, Chenzhong, Perdih, Andrej, Abulwerdi, Fardokht A, Chinnaswamy, Krishnapriya, Meagher, Jennifer L, Carlson, Jacob M, Khanna, May, Stuckey, Jeanne A, Nikolovska-Coleska, Zaneta
Published in Journal of medicinal chemistry (12.03.2020)
Published in Journal of medicinal chemistry (12.03.2020)
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Journal Article
PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity
Gozgit, Joseph M., Vasbinder, Melissa M., Abo, Ryan P., Kunii, Kaiko, Kuplast-Barr, Kristy G., Gui, Bin, Lu, Alvin Z., Molina, Jennifer R., Minissale, Elena, Swinger, Kerren K., Wigle, Tim J., Blackwell, Danielle J., Majer, Christina R., Ren, Yue, Niepel, Mario, Varsamis, Zacharenia A., Nayak, Sunaina P., Bamberg, Ellen, Mo, Jan-Rung, Church, W. David, Mady, Ahmed S.A., Song, Jeff, Utley, Luke, Rao, Patricia E., Mitchison, Timothy J., Kuntz, Kevin W., Richon, Victoria M., Keilhack, Heike
Published in Cancer cell (13.09.2021)
Published in Cancer cell (13.09.2021)
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Journal Article
The WD40 domain of FBXW7 is a poly(ADP-ribose)-binding domain that mediates the early DNA damage response
Zhang, Qiang, Mady, Ahmed S A, Ma, Yuanyuan, Ryan, Caila, Lawrence, Theodore S, Nikolovska-Coleska, Zaneta, Sun, Yi, Morgan, Meredith A
Published in Nucleic acids research (07.05.2019)
Published in Nucleic acids research (07.05.2019)
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Journal Article
A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo
Abulwerdi, Fardokht, Liao, Chenzhong, Liu, Meilan, Azmi, Asfar S, Aboukameel, Amro, Mady, Ahmed S A, Gulappa, Thippeswamy, Cierpicki, Tomasz, Owens, Scott, Zhang, Tao, Sun, Duxin, Stuckey, Jeanne A, Mohammad, Ramzi M, Nikolovska-Coleska, Zaneta
Published in Molecular cancer therapeutics (01.03.2014)
Published in Molecular cancer therapeutics (01.03.2014)
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Journal Article
Discovery of Mcl-1 inhibitors from integrated high throughput and virtual screening
Mady, Ahmed S. A., Liao, Chenzhong, Bajwa, Naval, Kump, Karson J., Abulwerdi, Fardokht A., Lev, Katherine L., Miao, Lei, Grigsby, Sierrah M., Perdih, Andrej, Stuckey, Jeanne A., Du, Yuhong, Fu, Haian, Nikolovska-Coleska, Zaneta
Published in Scientific reports (05.07.2018)
Published in Scientific reports (05.07.2018)
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Journal Article
Directed Modulation of Protein Kinase C Isozyme Selectivity with Bisubstrate-Based Inhibitors
van Wandelen, Loek T. M., van Ameijde, Jeroen, Mady, Ahmed S. A., Wammes, Angelique E. M., Bode, Alois, Poot, Alex J., Ruijtenbeek, Rob, Liskamp, Rob M. J.
Published in ChemMedChem (01.12.2012)
Published in ChemMedChem (01.12.2012)
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Journal Article
Characterization of TioQ, a type II thioesterase from the thiocoraline biosynthetic cluster
Mady, Ahmed S A, Zolova, Olga E, Millán, María Álvarez San, Villamizar, Germán, de la Calle, Fernando, Lombó, Felipe, Garneau-Tsodikova, Sylvie
Published in Molecular bioSystems (01.06.2011)
Published in Molecular bioSystems (01.06.2011)
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Journal Article
The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics
Giblin, William, Bringman-Rodenbarger, Lauren, Guo, Angela H, Kumar, Surinder, Monovich, Alexander C, Mostafa, Ahmed M, Skinner, Mary E, Azar, Michelle, Mady, Ahmed Sa, Chung, Carolina H, Kadambi, Namrata, Melong, Keith-Allen, Lee, Ho-Joon, Zhang, Li, Sajjakulnukit, Peter, Trefely, Sophie, Varner, Erika L, Iyer, Sowmya, Wang, Min, Wilmott, James S, Soyer, H Peter, Sturm, Richard A, Pritchard, Antonia L, Andea, Aleodor A, Scolyer, Richard A, Stark, Mitchell S, Scott, David A, Fullen, Douglas R, Bosenberg, Marcus W, Chandrasekaran, Sriram, Nikolovska-Coleska, Zaneta, Verhaegen, Monique E, Snyder, Nathaniel W, Rivera, Miguel N, Osterman, Andrei L, Lyssiotis, Costas A, Lombard, David B
Published in The Journal of clinical investigation (15.06.2021)
Published in The Journal of clinical investigation (15.06.2021)
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Journal Article
Directed Modulation of Protein KinaseC Isozyme Selectivity with Bisubstrate-Based Inhibitors
vanWandelen, Loek T. M, vanAmeijde, Jeroen, Mady, Ahmed S. A, Wammes, Angelique E. M, Bode, Alois, Poot, Alex J, Ruijtenbeek, Rob, Liskamp, Rob M. J
Published in ChemMedChem (01.12.2012)
Published in ChemMedChem (01.12.2012)
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Journal Article
Inside Cover: Directed Modulation of Protein Kinase C Isozyme Selectivity with Bisubstrate-Based Inhibitors (ChemMedChem 12/2012)
van Wandelen, Loek T. M., van Ameijde, Jeroen, Mady, Ahmed S. A., Wammes, Angelique E. M., Bode, Alois, Poot, Alex J., Ruijtenbeek, Rob, Liskamp, Rob M. J.
Published in ChemMedChem (01.12.2012)
Published in ChemMedChem (01.12.2012)
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Journal Article
Inside Cover: Directed Modulation of Protein KinaseC Isozyme Selectivity with Bisubstrate-Based Inhibitors (ChemMedChem 12/2012)
vanWandelen, Loek T. M, vanAmeijde, Jeroen, Mady, Ahmed S. A, Wammes, Angelique E. M, Bode, Alois, Poot, Alex J, Ruijtenbeek, Rob, Liskamp, Rob M. J
Published in ChemMedChem (01.12.2012)
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Published in ChemMedChem (01.12.2012)
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