Characterization of a Highly Conserved Domain within the Severe Acute Respiratory Syndrome Coronavirus Spike Protein S2 Domain with Characteristics of a Viral Fusion Peptide
MADU, Ikenna G, ROTH, Shoshannah L, BELOUZARD, Sandrine, WHITTAKER, Gary R
Published in Journal of Virology (01.08.2009)
Published in Journal of Virology (01.08.2009)
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Journal Article
A potent Lassa virus antiviral targets an arenavirus virulence determinant
Madu, Ikenna G, Files, Megan, Gharaibeh, Dima N, Moore, Amy L, Jung, Kie-Hoon, Gowen, Brian B, Dai, Dongcheng, Jones, Kevin F, Tyavanagimatt, Shanthakumar R, Burgeson, James R, Korth, Marcus J, Bedard, Kristin M, Iadonato, Shawn P, Amberg, Sean M
Published in PLoS pathogens (01.12.2018)
Published in PLoS pathogens (01.12.2018)
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Journal Article
Lassa antiviral LHF-535 protects guinea pigs from lethal challenge
Cashman, Kathleen A., Wilkinson, Eric R., Posakony, Jeffrey, Madu, Ikenna G., Tarcha, Eric J., Lustig, Kurt H., Korth, Marcus J., Bedard, Kristin M., Amberg, Sean M.
Published in Scientific reports (19.11.2022)
Published in Scientific reports (19.11.2022)
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Journal Article
Identification and Characterization of a New Chemotype of Noncovalent SENP Inhibitors
Madu, Ikenna G, Namanja, Andrew T, Su, Yang, Wong, Steven, Li, Yi-Jia, Chen, Yuan
Published in ACS chemical biology (19.07.2013)
Published in ACS chemical biology (19.07.2013)
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Journal Article
A Novel Class of HIV-1 Antiviral Agents Targeting HIV via a SUMOylation-Dependent Mechanism
Madu, Ikenna G., Li, Shirley, Li, Baozong, Li, Haitang, Chang, Tammy, Li, Yi-Jia, Vega, Ramir, Rossi, John, Yee, Jiing-Kuan, Zaia, John, Chen, Yuan
Published in Scientific reports (08.12.2015)
Published in Scientific reports (08.12.2015)
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Journal Article
Isoform-specific monobody inhibitors of small ubiquitin-related modifiers engineered using structure-guided library design
Gilbreth, Ryan N, Truong, Khue, Madu, Ikenna, Koide, Akiko, Wojcik, John B, Li, Nan-Sheng, Piccirilli, Joseph A, Chen, Yuan, Koide, Shohei
Published in Proceedings of the National Academy of Sciences - PNAS (10.05.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (10.05.2011)
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Journal Article
Heparan Sulfate Is a Selective Attachment Factor for the Avian Coronavirus Infectious Bronchitis Virus Beaudette
Madu, I.G, Chu, V.C, Lee, H, Regan, A.D, Bauman, B.E, Whittaker, G.R
Published in Avian diseases (01.03.2007)
Published in Avian diseases (01.03.2007)
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Journal Article
Elastase-mediated Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein at Discrete Sites within the S2 Domain<inline-graphic xlink:href="sbox.jpg"/>
Belouzard, Sandrine, Madu, Ikenna, Whittaker, Gary R
Published in The Journal of biological chemistry (27.05.2010)
Published in The Journal of biological chemistry (27.05.2010)
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Journal Article
IDENTIFICATION AND CHARACTERIZATION OF A NEW CHEMOTYPE OF NON-COVALENT SENP INHIBITORS
Madu, Ikenna G., Namanja, Andrew T., Su, Yang, Wong, Steven, Li, Yi-Jia, Chen, Yuan
Published in ACS chemical biology (01.05.2013)
Published in ACS chemical biology (01.05.2013)
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Journal Article
ANTI-VIRAL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF
Bedard, Kristin M, Kaiser, Shari, Fowler, Kerry W, Iadonato, Shawn P, Madu, Ikenna
Year of Publication 27.08.2020
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Year of Publication 27.08.2020
Patent
Anti-viral compounds, pharmaceutical compositions, and methods of use thereof
MADU, Ikenna, BEDARD, Kristin M, KAISER, Shari, FOWLER, Kerry W, IADONATO, Shawn P
Year of Publication 16.07.2020
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Year of Publication 16.07.2020
Patent
Anti-viral compounds, pharmaceutical compositions, and methods of use thereof
MADU, Ikenna, BEDARD, Kristin M, KAISER, Shari, FOWLER, Kerry W, IADONATO, Shawn P
Year of Publication 02.04.2020
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Year of Publication 02.04.2020
Patent
Anti-viral compounds, pharmaceutical compositions, and methods of use thereof
Bedard, Kristin M, Kaiser, Shari, Fowler, Kerry W, Iadonato, Shawn P, Madu, Ikenna
Year of Publication 12.12.2019
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Year of Publication 12.12.2019
Patent
ANTI-VIRAL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF
Bedard, Kristin M, Kaiser, Shari, Fowler, Kerry W, Iadonato, Shawn P, Madu, Ikenna
Year of Publication 03.01.2019
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Year of Publication 03.01.2019
Patent
Anti-viral compounds, pharmaceutical compositions, and methods of use thereof
Iadonato Shawn P, Fowler Kerry W, Kaiser Shari, Bedard Kristin M, Madu Ikenna
Year of Publication 06.02.2018
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Year of Publication 06.02.2018
Patent
ANTI-VIRAL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF
MADU, Ikenna, IADONATO, Shawn, P, KAISER, Shari, FOWLER, Kerry, W, BEDARD, Kristin, M
Year of Publication 01.11.2017
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Year of Publication 01.11.2017
Patent
ANTI-VIRAL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF
MADU, Ikenna, IADONATO, Shawn, P, KAISER, Shari, FOWLER, Kerry, W, BEDARD, Kristin, M
Year of Publication 15.03.2017
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Year of Publication 15.03.2017
Patent