Non-isoprenoid polyene natural products - structures and synthetic strategies
Madden, Katrina S, Mosa, Fathia A, Whiting, Andrew
Published in Organic & biomolecular chemistry (28.10.2014)
Published in Organic & biomolecular chemistry (28.10.2014)
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Journal Article
Mechanistic Investigation of the Androgen Receptor DNA-Binding Domain and Modulation via Direct Interactions with DNA Abasic Sites: Understanding the Mechanisms Involved in Castration-Resistant Prostate Cancer
Xu, Shangze, Kondal, Matthew D, Ahmad, Ayaz, Zhu, Ruidi, Fan, Lanyu, Zaborniak, Piotr, Madden, Katrina S, de Souza, João V, Bronowska, Agnieszka K
Published in International journal of molecular sciences (09.01.2023)
Published in International journal of molecular sciences (09.01.2023)
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Journal Article
A tubulin binding molecule drives differentiation of acute myeloid leukemia cells
Jackson, Thomas R., Vuorinen, Aini, Josa-Culleré, Laia, Madden, Katrina S., Conole, Daniel, Cogswell, Thomas J., Wilkinson, Isabel V.L., Kettyle, Laura M., Zhang, Douzi, O’Mahony, Alison, Gracias, Deanne, McCall, Lorna, Westwood, Robert, Terstappen, Georg C., Davies, Stephen G., Tate, Edward W., Wynne, Graham M., Vyas, Paresh, Russell, Angela J., Milne, Thomas A.
Published in iScience (19.08.2022)
Published in iScience (19.08.2022)
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A Phenotypic Screen Identifies a Compound Series That Induces Differentiation of Acute Myeloid Leukemia Cells In Vitro and Shows Antitumor Effects In Vivo
Josa-Culleré, Laia, Madden, Katrina S, Cogswell, Thomas J, Jackson, Thomas R, Carter, Tom S, Zhang, Douzi, Trevitt, Graham, Davies, Stephen G, Vyas, Paresh, Wynne, Graham M, Milne, Thomas A, Russell, Angela J
Published in Journal of medicinal chemistry (11.11.2021)
Published in Journal of medicinal chemistry (11.11.2021)
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Journal Article
Approaches to Styrenyl Building Blocks for the Synthesis of Polyene Xanthomonadin and its Analogues
Madden, Katrina S., Laroche, Benjamin, David, Sylvain, Batsanov, Andrei S., Thompson, Daniel, Knowles, Jonathan P., Whiting, Andrew
Published in European journal of organic chemistry (17.10.2018)
Published in European journal of organic chemistry (17.10.2018)
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Journal Article
Phenotypic screening identifies a trisubstituted imidazo[1,2-a]pyridine series that induces differentiation in multiple AML cell lines
Josa-Culleré, Laia, Galan, Sébastien R.G., Cogswell, Thomas J., Jackson, Thomas R., Jay-Smith, Morgan, Mola, Laura, Greaves, Christopher R., Carter, Tom S., Madden, Katrina S., Trott, Sophie, Zhang, Douzi, Bataille, Carole J.R., Davies, Stephen G., Vyas, Paresh, Milne, Thomas A., Naylor, Alan, Wynne, Graham M., Russell, Angela J.
Published in European journal of medicinal chemistry (05.10.2023)
Published in European journal of medicinal chemistry (05.10.2023)
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Journal Article
Using Nature's polyenes as templates: studies of synthetic xanthomonadin analogues and realising their potential as antioxidants
Madden, Katrina S, Jokhoo, Hans R. E, Conradi, Fabian D, Knowles, Jonathan P, Mullineaux, Conrad W, Whiting, Andrew
Published in Organic & biomolecular chemistry (10.04.2019)
Published in Organic & biomolecular chemistry (10.04.2019)
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Journal Article
Pilot Study to Quantify Palladium Impurities in Lead-like Compounds Following Commonly Used Purification Techniques
Chatzopoulou, Maria, Madden, Katrina S, Bromhead, Liam J, Greaves, Christopher, Cogswell, Thomas J, Da Silva Pinto, Solange, Galan, Sébastien R G, Georgiou, Irene, Kennedy, Matthew S, Kennett, Alice, Apps, Geraint, Russell, Angela J, Wynne, Graham M
Published in ACS medicinal chemistry letters (10.02.2022)
Published in ACS medicinal chemistry letters (10.02.2022)
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Journal Article
“Druggability” of the PAS domains of human PASK kinase, a therapeutic target for metabolic and liver disorders
Xu, Shangze, Fan, Lanyu, Zaborniak, Piotr, Zhu, Ruidi, Ji, Haoyuan, Madden, Katrina S., de Souza, João V., Bronowska, Agnieszka K.
Published in QRB discovery (02.02.2024)
Published in QRB discovery (02.02.2024)
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Journal Article
Correction: Non-isoprenoid polyene natural products - structures and synthetic strategies
Madden, Katrina S, Mosa, Fathia A, Whiting, Andrew
Published in Organic & biomolecular chemistry (28.11.2014)
Published in Organic & biomolecular chemistry (28.11.2014)
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Journal Article
Heck-Mizoroki coupling of vinyliodide and applications in the synthesis of dienes and trienesElectronic supplementary information (ESI) available: Experimental details. See DOI: 10.1039/c5cc03273c
Madden, Katrina S, David, Sylvain, Knowles, Jonathan P, Whiting, Andrew
Year of Publication 02.07.2015
Year of Publication 02.07.2015
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Journal Article
A phenotypic screen identifies a compound series that induces differentiation of acute myeloid leukemia cells in vitro and shows anti-tumour effects in vivo
Josa-Culleré, Laia, Madden, Katrina S, Cogswell, Thomas J, Jackson, Thomas R, Carter, Tom S, Zhang, Douzi, Trevitt, Graham, Davies, Stephen G, Vyas, Paresh, Wynne, Graham M, Milne, Thomas A, Russell, Angela J
Published in bioRxiv (18.12.2020)
Published in bioRxiv (18.12.2020)
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Paper
A novel tubulin binding molecule drives differentiation of acute myeloid leukaemia cells
Jackson, Thomas R, Vuorinen, Aini, Josa-Cullere, Laia, Madden, Katrina S, Conole, Daniel, Cogswell, Thomas J, Wilkinson, Isabel Vl, Kettyle, Laura M, Zhang, Douzi, O'mahony, Alison, Gracias, Deanne, Mccall, Lorna, Westwood, Robert, Terstappen, Georg C, Davies, Stephen G, Tate, Edward William, Wynne, Graham M, Vyas, Paresh, Russell, Angela, Milne, Thomas
Published in bioRxiv (03.06.2021)
Published in bioRxiv (03.06.2021)
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