Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase
Cai, Yi, Jaecklein, Eleni, Mackenzie, Jared S, Papavinasasundaram, Kadamba, Olive, Andrew J, Chen, Xinchun, Steyn, Adrie J C, Sassetti, Christopher M
Published in PLoS pathogens (01.07.2021)
Published in PLoS pathogens (01.07.2021)
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Journal Article
Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis
Saini, Vikram, Chinta, Krishna C., Reddy, Vineel P., Glasgow, Joel N., Stein, Asaf, Lamprecht, Dirk A., Rahman, Md. Aejazur, Mackenzie, Jared S., Truebody, Barry E., Adamson, John H., Kunota, Tafara T. R., Bailey, Shannon M., Moellering, Douglas R., Lancaster, Jack R., Steyn, Adrie J. C.
Published in Nature communications (28.01.2020)
Published in Nature communications (28.01.2020)
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Journal Article
Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis
Mackenzie, Jared S., Lamprecht, Dirk A., Asmal, Rukaya, Adamson, John H., Borah, Khushboo, Beste, Dany J. V., Lee, Bei Shi, Pethe, Kevin, Rousseau, Simon, Krieger, Inna, Sacchettini, James C., Glasgow, Joel N., Steyn, Adrie J. C.
Published in Nature communications (30.11.2020)
Published in Nature communications (30.11.2020)
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Journal Article
Dual inhibition of the terminal oxidases eradicates antibiotic‐tolerant Mycobacterium tuberculosis
Lee, Bei Shi, Hards, Kiel, Engelhart, Curtis A, Hasenoehrl, Erik J, Kalia, Nitin P, Mackenzie, Jared S, Sviriaeva, Ekaterina, Chong, Shi Min Sherilyn, Manimekalai, Malathy Sony S, Koh, Vanessa H, Chan, John, Xu, Jiayong, Alonso, Sylvie, Miller, Marvin J, Steyn, Adrie J C, Grüber, Gerhard, Schnappinger, Dirk, Berney, Michael, Cook, Gregory M, Moraski, Garrett C, Pethe, Kevin
Published in EMBO molecular medicine (11.01.2021)
Published in EMBO molecular medicine (11.01.2021)
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Journal Article
Mycobacterium tuberculosis H2S Functions as a Sink to Modulate Central Metabolism, Bioenergetics, and Drug Susceptibility
Kunota, Tafara T. R., Rahman, Md. Aejazur, Truebody, Barry E., Mackenzie, Jared S., Saini, Vikram, Lamprecht, Dirk A., Adamson, John H., Sevalkar, Ritesh R., Lancaster, Jack R., Berney, Michael, Glasgow, Joel N., Steyn, Adrie J. C.
Published in Antioxidants (13.08.2021)
Published in Antioxidants (13.08.2021)
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Journal Article
Identification of Chemical Scaffolds That Inhibit the Mycobacterium tuberculosis Respiratory Complex Succinate Dehydrogenase
Adolph, Cara, Hards, Kiel, Williams, Zoe C., Cheung, Chen-Yi, Keighley, Laura M., Jowsey, William J., Kyte, Matson, Inaoka, Daniel Ken, Kita, Kiyoshi, Mackenzie, Jared S., Steyn, Adrie J.C., Li, Zhengqiu, Yan, Ming, Tian, Guo-Bao, Zhang, Tianyu, Ding, Xiaobo, Furkert, Daniel P., Brimble, Margaret A., Hickey, Anthony J.R., McNeil, Matthew B., Cook, Gregory M.
Published in ACS infectious diseases (11.10.2024)
Published in ACS infectious diseases (11.10.2024)
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Journal Article
Mycobacterium tuberculosis senses host Interferon-γ via the membrane protein MmpL10
Ahmed, Mohamed, Mackenzie, Jared, Tezera, Liku, Krause, Robert, Truebody, Barry, Garay-Baquero, Diana, Vallejo, Andres, Govender, Katya, Adamson, John, Fisher, Hayden, Essex, Jonathan W., Mansour, Salah, Elkington, Paul, Steyn, Adrie J. C., Leslie, Alasdair
Published in Communications biology (01.12.2022)
Published in Communications biology (01.12.2022)
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Journal Article
Light Forge: A Microfluidic DNA Melting-based Tuberculosis Test
Mbano, Ian M, Mandizvo, Tawanda, Rogich, Jerome, Kunota, Tafara T R, Mackenzie, Jared S, Pillay, Manormoney, Balagaddé, Frederick K
Published in The journal of applied laboratory medicine (01.05.2020)
Published in The journal of applied laboratory medicine (01.05.2020)
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Journal Article
Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites
Beteck, Richard M., Seldon, Ronnett, Coertzen, Dina, van der Watt, Mariëtte E., Reader, Janette, Mackenzie, Jared S., Lamprecht, Dirk A., Abraham, Matthew, Eribez, Korina, Müller, Joachim, Rui, Feng, Zhu, Guang, de Grano, Ruel Valerio, Williams, Ian D., Smit, Frans J., Steyn, Adrie J. C., Winzeler, Elizabeth A., Hemphill, Andrew, Birkholtz, Lyn-Marie, Warner, Digby F., N’Da, David D., Haynes, Richard K.
Published in Communications chemistry (02.10.2018)
Published in Communications chemistry (02.10.2018)
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Journal Article
Engineered Mycobacteriophage TM4::GeNL Rapidly Determines Bedaquiline, Pretomanid, Linezolid, Rifampicin, and Clofazimine Sensitivity in Mycobacterium tuberculosis Clinical Isolates
Rajagopalan, Saranathan, Rourke, Amy K, Asare, Emmanuel, Kohlerschmidt, Donna J, Das, Lahari, Ngema, Senamile L, Mulholland, Claire V, Vilchèze, Catherine, Mahalingam, Vaishnavi, Moodley, Sashen, Truebody, Barry, Mackenzie, Jared, Steyn, Adrie J C, Perumal, Rubeshan, Berney, Michael, Larsen, Michelle H, O'Donnell, Max R, Escuyer, Vincent E, Jacobs, Jr, William R
Published in The Journal of infectious diseases (16.10.2024)
Published in The Journal of infectious diseases (16.10.2024)
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Journal Article
SCREENING METHOD AND APPARATUS FOR DRUG EFFLUX DISPLACEMENT
BALAGADDE Frederick Kiguli, MACKENZIE, Jared Stuart, MYRICK, Alissa Barbara
Year of Publication 31.07.2019
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Year of Publication 31.07.2019
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