Characterising covalent warhead reactivity
Martin, James S., MacKenzie, Claire J., Fletcher, Daniel, Gilbert, Ian H.
Published in Bioorganic & medicinal chemistry (15.05.2019)
Published in Bioorganic & medicinal chemistry (15.05.2019)
Get full text
Journal Article
Synthesis of a Series of Diaminoindoles
Martin, James S, Mackenzie, Claire J, Gilbert, Ian H
Published in Journal of organic chemistry (03.09.2021)
Published in Journal of organic chemistry (03.09.2021)
Get full text
Journal Article
Respiratory flexibility in response to inhibition of cytochrome C oxidase in Mycobacterium tuberculosis
Arora, Kriti, Ochoa-Montaño, Bernardo, Tsang, Patricia S, Blundell, Tom L, Dawes, Stephanie S, Mizrahi, Valerie, Bayliss, Tracy, Mackenzie, Claire J, Cleghorn, Laura A T, Ray, Peter C, Wyatt, Paul G, Uh, Eugene, Lee, Jinwoo, Barry, 3rd, Clifton E, Boshoff, Helena I
Published in Antimicrobial agents and chemotherapy (01.11.2014)
Published in Antimicrobial agents and chemotherapy (01.11.2014)
Get full text
Journal Article
Determination of orally administered 1,8-Cineol in nasal polyp tissues from chronic rhinosinusitis patients using gas chromatography: mass spectrometry
MacKenzie, Claire, Goerke, Thomas, Buecking, Mark, Heidemann, Mathias, Leichtle, Anke, Ringbeck, Benedikt, Möllenkolk, Friederike, Ploch, Michael, Bruchhage, Karl-Ludwig, Pries, Ralph
Published in Scientific reports (03.03.2023)
Published in Scientific reports (03.03.2023)
Get full text
Journal Article
Application of an NMR/Crystallography Fragment Screening Platform for the Assessment and Rapid Discovery of New HIV‐CA Binding Fragments
Lang, Stuart, Fletcher, Daniel A., Petit, Alain‐Pierre, Luise, Nicola, Fyfe, Paul, Zuccotto, Fabio, Porter, David, Hope, Anthony, Bellany, Fiona, Kerr, Catrina, Mackenzie, Claire J., Wyatt, Paul G., Gray, David W.
Published in ChemMedChem (02.07.2024)
Published in ChemMedChem (02.07.2024)
Get full text
Journal Article
Design and Synthesis of Covalent Inhibitors of FabA
Martin, James S., Mackenzie, Claire J., Lin, De, Homeyer, Nadine, Gray, David W., Zuccotto, Fabio, Gilbert, Ian H.
Published in ACS omega (11.04.2023)
Published in ACS omega (11.04.2023)
Get full text
Journal Article
Correction for Arora et al., "Respiratory Flexibility in Response to Inhibition of Cytochrome c Oxidase in Mycobacterium tuberculosis "
Arora, Kriti, Ochoa-Montaño, Bernardo, Tsang, Patricia S, Blundell, Tom L, Dawes, Stephanie S, Mizrahi, Valerie, Bayliss, Tracy, Mackenzie, Claire J, Cleghorn, Laura A T, Ray, Peter C, Wyatt, Paul G, Uh, Eugene, Lee, Jinwoo, Barry, 3rd, Clifton E, Boshoff, Helena I
Published in Antimicrobial agents and chemotherapy (01.09.2017)
Published in Antimicrobial agents and chemotherapy (01.09.2017)
Get full text
Journal Article
Discovery of an Allosteric Binding Site in Kinetoplastid Methionyl-tRNA Synthetase
Torrie, Leah S, Robinson, David A, Thomas, Michael G, Hobrath, Judith V, Shepherd, Sharon M, Post, John M, Ko, Eun-Jung, Ferreira, Rafael Alves, Mackenzie, Claire J, Wrobel, Karolina, Edwards, Darren P, Gilbert, Ian H, Gray, David W, Fairlamb, Alan H, De Rycker, Manu
Published in ACS infectious diseases (08.05.2020)
Published in ACS infectious diseases (08.05.2020)
Get full text
Journal Article
Exploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug design
Pizarro, Juan Carlos, Hills, Tanya, Senisterra, Guillermo, Wernimont, Amy K, Mackenzie, Claire, Norcross, Neil R, Ferguson, Michael A J, Wyatt, Paul G, Gilbert, Ian H, Hui, Raymond
Published in PLoS neglected tropical diseases (01.10.2013)
Published in PLoS neglected tropical diseases (01.10.2013)
Get full text
Journal Article
Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivo efficacy against visceral leishmaniasis
Thomas, Michael G, De Rycker, Manu, Ajakane, Myriam, Crouch, Sabrinia D, Campbell, Lorna, Daugan, Alain, Fra, Gloria, Guerrero, César, Mackenzie, Claire J, MacLean, Lorna, Manthri, Sujatha, Martin, Franck, Norval, Suzanne, Osuna-Cabello, Maria, Riley, Jennifer, Shishikura, Yoko, Miguel-Siles, Juan, Simeons, Frederick R C, Stojanovski, Laste, Thomas, John, Thompson, Stephen, Velasco, Raul F, Fiandor, Jose M, Wyatt, Paul G, Read, Kevin D, Gilbert, Ian H, Miles, Timothy J
Published in MedChemComm (01.10.2020)
Published in MedChemComm (01.10.2020)
Get full text
Journal Article
Identification of 6-amino-1 H -pyrazolo[3,4- d ]pyrimidines with in vivo efficacy against visceral leishmaniasis
Thomas, Michael G, De Rycker, Manu, Ajakane, Myriam, Crouch, Sabrinia D, Campbell, Lorna, Daugan, Alain, Fra, Gloria, Guerrero, César, Mackenzie, Claire J, MacLean, Lorna, Manthri, Sujatha, Martin, Franck, Norval, Suzanne, Osuna-Cabello, Maria, Riley, Jennifer, Shishikura, Yoko, Miguel-Siles, Juan, Simeons, Frederick R C, Stojanovski, Laste, Thomas, John, Thompson, Stephen, Velasco, Raul F, Fiandor, Jose M, Wyatt, Paul G, Read, Kevin D, Gilbert, Ian H, Miles, Timothy J
Published in RSC medicinal chemistry (01.10.2020)
Published in RSC medicinal chemistry (01.10.2020)
Get full text
Journal Article
Complication Rates and Short-Term Outcomes After Operative Hammertoe Correction in Older Patients
Mueller, Claire Mackenzie, Boden, Stephanie Ann, Boden, Allison Lee, Maidman, Samuel David, Cutler, Anya, Mignemi, Danielle, Bariteau, Jason
Published in Foot & ankle international (01.06.2018)
Published in Foot & ankle international (01.06.2018)
Get more information
Journal Article
Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target
Wilson, Caroline, Ray, Peter, Zuccotto, Fabio, Hernandez, Jorge, Aggarwal, Anup, Mackenzie, Claire, Caldwell, Nicola, Taylor, Malcolm, Huggett, Margaret, Mathieson, Michael, Murugesan, Dinakaran, Smith, Alasdair, Davis, Susan, Cocco, Mattia, Parai, Maloy K, Acharya, Arjun, Tamaki, Fabio, Scullion, Paul, Epemolu, Ola, Riley, Jennifer, Stojanovski, Laste, Lopez-Román, Eva Maria, Torres-Gómez, Pedro Alfonso, Toledo, Ana Maria, Guijarro-Lopez, Laura, Camino, Isabel, Engelhart, Curtis A, Schnappinger, Dirk, Massoudi, Lisa M, Lenaerts, Anne, Robertson, Gregory T, Walpole, Chris, Matthews, David, Floyd, David, Sacchettini, James C, Read, Kevin D, Encinas, Lourdes, Bates, Robert H, Green, Simon R, Wyatt, Paul G
Published in Journal of medicinal chemistry (13.01.2022)
Published in Journal of medicinal chemistry (13.01.2022)
Get full text
Journal Article
Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis
Thomas, Michael G, De Rycker, Manu, Ajakane, Myriam, Albrecht, Sébastian, Álvarez-Pedraglio, Ana Isabel, Boesche, Markus, Brand, Stephen, Campbell, Lorna, Cantizani-Perez, Juan, Cleghorn, Laura A.T, Copley, Royston C.B, Crouch, Sabrinia D, Daugan, Alain, Drewes, Gerard, Ferrer, Santiago, Ghidelli-Disse, Sonja, Gonzalez, Silvia, Gresham, Stephanie L, Hill, Alan P, Hindley, Sean J, Lowe, Rhiannon M, MacKenzie, Claire J, MacLean, Lorna, Manthri, Sujatha, Martin, Franck, Miguel-Siles, Juan, Nguyen, Van Loc, Norval, Suzanne, Osuna-Cabello, Maria, Woodland, Andrew, Patterson, Stephen, Pena, Imanol, Quesada-Campos, Maria Teresa, Reid, Iain H, Revill, Charlotte, Riley, Jennifer, Ruiz-Gomez, Jose Ramon, Shishikura, Yoko, Simeons, Frederick R.C, Smith, Alasdair, Smith, Victoria C, Spinks, Daniel, Stojanovski, Laste, Thomas, John, Thompson, Stephen, Underwood, Tim, Gray, David W, Fiandor, Jose M, Gilbert, Ian H, Wyatt, Paul G, Read, Kevin D, Miles, Timothy J
Published in Journal of medicinal chemistry (14.02.2019)
Published in Journal of medicinal chemistry (14.02.2019)
Get full text
Journal Article
Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis
Park, Yumi, Pacitto, Angela, Bayliss, Tracy, Cleghorn, Laura A. T, Wang, Zhe, Hartman, Travis, Arora, Kriti, Ioerger, Thomas R, Sacchettini, Jim, Rizzi, Menico, Donini, Stefano, Blundell, Tom L, Ascher, David B, Rhee, Kyu, Breda, Ardala, Zhou, Nian, Dartois, Veronique, Jonnala, Surendranadha Reddy, Via, Laura E, Mizrahi, Valerie, Epemolu, Ola, Stojanovski, Laste, Simeons, Fred, Osuna-Cabello, Maria, Ellis, Lucy, MacKenzie, Claire J, Smith, Alasdair R. C, Davis, Susan H, Murugesan, Dinakaran, Buchanan, Kirsteen I, Turner, Penelope A, Huggett, Margaret, Zuccotto, Fabio, Rebollo-Lopez, Maria Jose, Lafuente-Monasterio, Maria Jose, Sanz, Olalla, Diaz, Gracia Santos, Lelièvre, Joël, Ballell, Lluis, Selenski, Carolyn, Axtman, Matthew, Ghidelli-Disse, Sonja, Pflaumer, Hannah, Bösche, Markus, Drewes, Gerard, Freiberg, Gail M, Kurnick, Matthew D, Srikumaran, Myron, Kempf, Dale J, Green, Simon R, Ray, Peter C, Read, Kevin, Wyatt, Paul, Barry, Clifton E, Boshoff, Helena I
Published in ACS infectious diseases (13.01.2017)
Published in ACS infectious diseases (13.01.2017)
Get full text
Journal Article
Screening of a Novel Fragment Library with Functional Complexity against Mycobacterium tuberculosis InhA
Prati, Federica, Zuccotto, Fabio, Fletcher, Daniel, Convery, Maire A., Fernandez‐Menendez, Raquel, Bates, Robert, Encinas, Lourdes, Zeng, Jingkun, Chung, Chun‐wa, De Dios Anton, Paco, Mendoza‐Losana, Alfonso, Mackenzie, Claire, Green, Simon R., Huggett, Margaret, Barros, David, Wyatt, Paul G., Ray, Peter C.
Published in ChemMedChem (06.04.2018)
Published in ChemMedChem (06.04.2018)
Get full text
Journal Article
Exploring the Trypanosoma brucei Hsp83 Potential as a Target for Structure Guided Drug Design: e2492
Pizarro, Juan Carlos, Hills, Tanya, Senisterra, Guillermo, Wernimont, Amy K, Mackenzie, Claire, Norcross, Neil R, Ferguson, Michael AJ, Wyatt, Paul G, Gilbert, Ian H, Hui, Raymond
Published in PLoS neglected tropical diseases (01.10.2013)
Published in PLoS neglected tropical diseases (01.10.2013)
Get full text
Journal Article
Identification of 6-amino-1-pyrazolo[3,4-]pyrimidines with efficacy against visceral leishmaniasis
Thomas, Michael G, De Rycker, Manu, Ajakane, Myriam, Crouch, Sabrinia D, Campbell, Lorna, Daugan, Alain, Fra, Gloria, Guerrero, César, Mackenzie, Claire J, MacLean, Lorna, Manthri, Sujatha, Martin, Franck, Norval, Suzanne, Osuna-Cabello, Maria, Riley, Jennifer, Shishikura, Yoko, Miguel-Siles, Juan, Simeons, Frederick R. C, Stojanovski, Laste, Thomas, John, Thompson, Stephen, Velasco, Raul F, Fiandor, Jose M, Wyatt, Paul G, Read, Kevin D, Gilbert, Ian H, Miles, Timothy J
Published in RSC medicinal chemistry (21.10.2020)
Published in RSC medicinal chemistry (21.10.2020)
Get full text
Journal Article
Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivo efficacy against visceral leishmaniasis† †Electronic supplementary information (ESI) available. See DOI: 10.1039/d0md00203h
Thomas, Michael G., De Rycker, Manu, Ajakane, Myriam, Crouch, Sabrinia D., Campbell, Lorna, Daugan, Alain, Fra, Gloria, Guerrero, César, Mackenzie, Claire J., MacLean, Lorna, Manthri, Sujatha, Martin, Franck, Norval, Suzanne, Osuna-Cabello, Maria, Riley, Jennifer, Shishikura, Yoko, Miguel-Siles, Juan, Simeons, Frederick R. C., Stojanovski, Laste, Thomas, John, Thompson, Stephen, Velasco, Raul F., Fiandor, Jose M., Wyatt, Paul G., Read, Kevin D., Gilbert, Ian H., Miles, Timothy J.
Published in RSC medicinal chemistry (06.08.2020)
Published in RSC medicinal chemistry (06.08.2020)
Get full text
Journal Article