Baricitinib versus Placebo or Adalimumab in Rheumatoid Arthritis
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Published in The New England journal of medicine (16.02.2017)
Published in The New England journal of medicine (16.02.2017)
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Comparison of baricitinib, upadacitinib, and tofacitinib mediated regulation of cytokine signaling in human leukocyte subpopulations
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Published in Arthritis research & therapy (02.08.2019)
Published in Arthritis research & therapy (02.08.2019)
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JAK1/JAK2 inhibition by baricitinib in diabetic kidney disease: results from a Phase 2 randomized controlled clinical trial
Tuttle, Katherine R, Brosius, 3rd, Frank C, Adler, Sharon G, Kretzler, Matthias, Mehta, Ravindra L, Tumlin, James A, Tanaka, Yoshiya, Haneda, Masakazu, Liu, Jiajun, Silk, Maria E, Cardillo, Tracy E, Duffin, Kevin L, Haas, Joseph V, Macias, William L, Nunes, Fabio P, Janes, Jonathan M
Published in Nephrology, dialysis, transplantation (01.11.2018)
Published in Nephrology, dialysis, transplantation (01.11.2018)
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Pharmacokinetics, Pharmacodynamics, and Proposed Dosing of the Oral JAK1 and JAK2 Inhibitor Baricitinib in Pediatric and Young Adult CANDLE and SAVI Patients
Kim, Hanna, Brooks, Kristina M, Tang, Cheng Cai, Wakim, Paul, Blake, Mary, Brooks, Stephen R, Montealegre Sanchez, Gina A, de Jesus, Adriana A, Huang, Yan, Tsai, Wanxia Li, Gadina, Massimo, Prakash, Apurva, Janes, Jonathan Marcus, Zhang, Xin, Macias, William L, Kumar, Parag, Goldbach-Mansky, Raphaela
Published in Clinical pharmacology and therapeutics (01.08.2018)
Published in Clinical pharmacology and therapeutics (01.08.2018)
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Drotrecogin alfa (activated) in children with severe sepsis: a multicentre phase III randomised controlled trial
Nadel, Simon, FRCP, Goldstein, Brahm, MD, Williams, Mark D, MD, Dalton, Heidi, MD, Peters, Mark, PhD, Macias, William L, MD, Abd-Allah, Shamel A, MD, Levy, Howard, FRCP, Angle, Robinette, RN, Wang, Dazhe, PhD, Sundin, David P, PhD, Giroir, Brett, Dr
Published in The Lancet (British edition) (10.03.2007)
Published in The Lancet (British edition) (10.03.2007)
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Recombinant Human Activated Protein C for the Postexposure Treatment of Ebola Hemorrhagic Fever
Hensley, Lisa E., Stevens, Edward L., Yan, S. Betty, Geisbert, Joan B., Macias, William L., Larsen, Tom, Daddario-DiCaprio, Kathleen M., Cassell, Gail H., Jahrling, Peter B., Geisbert, Thomas W.
Published in The Journal of infectious diseases (15.11.2007)
Published in The Journal of infectious diseases (15.11.2007)
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Wong, Hector R, Cvijanovich, Natalie, Wheeler, Derek S, Bigham, Michael T, Monaco, Marie, Odoms, Kelli, Macias, William L, Williams, Mark D
Published in American journal of respiratory and critical care medicine (01.08.2008)
Published in American journal of respiratory and critical care medicine (01.08.2008)
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Elevated Plasma Concentrations of IL-6 and Elevated APACHE II Score Predict Acute Kidney Injury in Patients with Severe Sepsis
Chawla, Lakhmir S, Seneff, Michael G, Nelson, David R, Williams, Mark, Levy, Howard, Kimmel, Paul L, Macias, William L
Published in Clinical journal of the American Society of Nephrology (01.01.2007)
Published in Clinical journal of the American Society of Nephrology (01.01.2007)
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Subcutaneous batoclimab in generalized myasthenia gravis: Results from a Phase 2a trial with an open‐label extension
Nowak, Richard J., Breiner, Ari, Bril, Vera, Allen, Jeffrey A., Khan, Shaida, Levine, Todd, Jacobs, Daniel H., Sahagian, Gregory, Siddiqi, Zaeem A., Xu, Jing, Macias, William L., Benatar, Michael, Adams, Laurence, Genge, Angela, Habib, Ali, Hinton, John L., Holmlund, Tomas H., Jacobs, Daniel H., Lange, Dale J., Nicolle, Michael W., Phan, Han C., Silvestri, Nicholas J., Small, George A., Yegiaian, Sharon
Published in Annals of clinical and translational neurology (01.01.2024)
Published in Annals of clinical and translational neurology (01.01.2024)
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Relationship between exposure to prasugrel active metabolite and clinical outcomes in the TRITON-TIMI 38 substudy
Riesmeyer, Jeffrey S, Salazar, Daniel E, Weerakkody, Govinda J, Ni, Lan, Wrishko, Rebecca E, Ernest, 2nd, C Steven, Luo, Junxiang, Li, Ying G, Small, David S, Rohatagi, Shashank, Macias, William L
Published in Journal of clinical pharmacology (01.06.2012)
Published in Journal of clinical pharmacology (01.06.2012)
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Protein C concentrations in severe sepsis: an early directional change in plasma levels predicts outcome
Shorr, Andrew F, Bernard, Gordon R, Dhainaut, Jean-Francois, Russell, James R, Macias, William L, Nelson, David R, Sundin, David P
Published in Critical care (London, England) (01.01.2006)
Published in Critical care (London, England) (01.01.2006)
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Safety Profile of Baricitinib in Patients with Active Rheumatoid Arthritis with over 2 Years Median Time in Treatment
Smolen, Josef S, Genovese, Mark C, Takeuchi, Tsutomu, Hyslop, David L, Macias, William L, Rooney, Terence, Chen, Lei, Dickson, Christina L, Riddle Camp, Jennifer, Cardillo, Tracy E, Ishii, Taeko, Winthrop, Kevin L
Published in Journal of rheumatology (01.01.2019)
Published in Journal of rheumatology (01.01.2019)
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Journal Article
Baricitinib in Patients with Refractory Rheumatoid Arthritis
Genovese, Mark C, Kremer, Joel, Zamani, Omid, Ludivico, Charles, Krogulec, Marek, Xie, Li, Beattie, Scott D, Koch, Alisa E, Cardillo, Tracy E, Rooney, Terence P, Macias, William L, de Bono, Stephanie, Schlichting, Douglas E, Smolen, Josef S
Published in The New England journal of medicine (31.03.2016)
Published in The New England journal of medicine (31.03.2016)
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JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies
Sanchez, Gina A Montealegre, Reinhardt, Adam, Ramsey, Suzanne, Wittkowski, Helmut, Hashkes, Philip J, Berkun, Yackov, Schalm, Susanne, Murias, Sara, Dare, Jason A, Brown, Diane, Stone, Deborah L, Gao, Ling, Klausmeier, Thomas, Foell, Dirk, de Jesus, Adriana A, Chapelle, Dawn C, Kim, Hanna, Dill, Samantha, Colbert, Robert A, Failla, Laura, Kost, Bahar, O'Brien, Michelle, Reynolds, James C, Folio, Les R, Calvo, Katherine R, Paul, Scott M, Weir, Nargues, Brofferio, Alessandra, Soldatos, Ariane, Biancotto, Angelique, Cowen, Edward W, Digiovanna, John J, Gadina, Massimo, Lipton, Andrew J, Hadigan, Colleen, Holland, Steven M, Fontana, Joseph, Alawad, Ahmad S, Brown, Rebecca J, Rother, Kristina I, Heller, Theo, Brooks, Kristina M, Kumar, Parag, Brooks, Stephen R, Waldman, Meryl, Singh, Harsharan K, Nickeleit, Volker, Silk, Maria, Prakash, Apurva, Janes, Jonathan M, Ozen, Seza, Wakim, Paul G, Brogan, Paul A, Macias, William L, Goldbach-Mansky, Raphaela
Published in The Journal of clinical investigation (01.07.2018)
Published in The Journal of clinical investigation (01.07.2018)
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Safety and efficacy of baricitinib at 24 weeks in patients with rheumatoid arthritis who have had an inadequate response to methotrexate
Keystone, Edward C, Taylor, Peter C, Drescher, Edit, Schlichting, Douglas E, Beattie, Scott D, Berclaz, Pierre-Yves, Lee, Chin H, Fidelus-Gort, Rosanne K, Luchi, Monica E, Rooney, Terence P, Macias, William L, Genovese, Mark C
Published in Annals of the rheumatic diseases (01.02.2015)
Published in Annals of the rheumatic diseases (01.02.2015)
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Cytochrome P450 Genetic Polymorphisms and the Response to Prasugrel: Relationship to Pharmacokinetic, Pharmacodynamic, and Clinical Outcomes
MEGA, Jessica L, CLOSE, Sandra L, SABATINE, Marc S, WIVIOTT, Stephen D, LEI SHEN, HOCKETT, Richard D, BRANDT, John T, WALKER, Joseph R, ANTMAN, Elloitt M, MACIAS, William L, BRAUNWALD, Eugene
Published in Circulation (New York, N.Y.) (19.05.2009)
Published in Circulation (New York, N.Y.) (19.05.2009)
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Drotrecogin Alfa (Activated) in Adults with Septic Shock
Ranieri, V. Marco, Thompson, B. Taylor, Barie, Philip S, Dhainaut, Jean-François, Douglas, Ivor S, Finfer, Simon, Gårdlund, Bengt, Marshall, John C, Rhodes, Andrew, Artigas, Antonio, Payen, Didier, Tenhunen, Jyrki, Al-Khalidi, Hussein R, Thompson, Vivian, Janes, Jonathan, Macias, William L, Vangerow, Burkhard, Williams, Mark D
Published in The New England journal of medicine (31.05.2012)
Published in The New England journal of medicine (31.05.2012)
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Proof-of-concept and Randomized, Placebo-controlled Trials of an FcRn Inhibitor, Batoclimab, for Thyroid Eye Disease
Kahaly, George J, Dolman, Peter J, Wolf, Jan, Giers, Bert C, Elflein, Heike M, Jain, Amy P, Srinivasan, Ashok, Hadjiiski, Lubomir, Jordan, David, Bradley, Elizabeth A, Stan, Marius N, Eckstein, Anja, Pitz, Susanne, Vorländer, Christian, Wester, Sara T, Nguyen, John, Tucker, Nancy, Sales-Sanz, Marco, Feldon, Steven E, Nelson, Christine C, Hardy, Isabelle, Abia-Serrano, Maravillas, Tedeschi, Philip, Janes, Jonathan M, Xu, Jing, Vue, Peter, Macias, William L, Douglas, Raymond S
Published in The journal of clinical endocrinology and metabolism (17.11.2023)
Published in The journal of clinical endocrinology and metabolism (17.11.2023)
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Journal Article
Response to baricitinib based on prior biologic use in patients with refractory rheumatoid arthritis
Genovese, Mark C, Kremer, Joel M, Kartman, Cynthia E, Schlichting, Douglas E, Xie, Li, Carmack, Tara, Pantojas, Carlos, Sanchez Burson, Juan, Tony, Hans-Peter, Macias, William L, Rooney, Terence P, Smolen, Josef S
Published in Rheumatology (Oxford, England) (01.05.2018)
Published in Rheumatology (Oxford, England) (01.05.2018)
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