INBRX-120, a CD8α-targeted detuned IL-2 that selectively expands and activates tumoricidal effector cells for safe and durable in vivo responses
Sulzmaier, Florian J, Kern, Nadja, Ahn, Sae Jeong, Polovina, Anya, Ho, Jason, Hussain, Abrahim, Cyprus, Garrett, Macedo, Chelsie, Pandit, Rajay, Crago, William, Rowell, Emily, Timmer, John C, Eckelman, Brendan P
Published in Journal for immunotherapy of cancer (01.01.2023)
Published in Journal for immunotherapy of cancer (01.01.2023)
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12 Key pharmacokinetic and pharmacodynamic parameters that correlate with the anti-tumor activity of a bispecific PD-L1 conditional 4–1BB agonist
Kinkead, Heather, Macedo, Chelsie, Sanabria, Angelica, Cyprus, Garrett, Pandit, Rajay, Kalabus, James, Becklund, Bryan, Sulzmaier, Florian, Timmer, John, Deveraux, Quinn, Eckelman, Brendan, Heidt, Analeah
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
722 INBRX-121 is an NKp46-targeted detuned IL-2 with antitumor activity as a monotherapy or in combination with multiple cancer immunotherapy modalities
Sulzmaier, Florian, Kinkead, Heather, Polovina, Anya, Kern, Nadja, Sanabria, Angelica, Macedo, Chelsie, Hussain, Abrahim, Ahn, Sae Jeong, Pandit, Rajay, Crago, William, Timmer, John, Heidt, Analeah, Eckelman, Brendan
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
Abstract 3513: INBRX-121, a safe and efficacious molecular targeted cytokine that enhances NK cell-mediated tumor killing
Kinkead, Heather, Sulzmaier, Florian J., Polovina, Anya, Kern, Nadja, Sanabria, Angelica, Ho, Jason, Macedo, Chelsie, Henderson, Ryan, Hussain, Abrahim, Pandit, Rajay, Crago, William, Rowell, Emily, Eckelman, Brendan P.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
CD123-binding polypeptides and uses thereof
Timmer, John C, Eckelman, Brendan P, Macedo, Chelsie, Jones, Kyle, Ma, Milton, Crago, William, Hollands, Andrew
Year of Publication 05.03.2024
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Year of Publication 05.03.2024
Patent
CD123-Binding Polypeptides and Uses Thereof
Timmer, John C, Eckelman, Brendan P, Macedo, Chelsie, Jones, Kyle, Ma, Milton, Crago, William, Hollands, Andrew
Year of Publication 02.03.2023
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Year of Publication 02.03.2023
Patent
CD123-binding polypeptides and uses thereof
Timmer, John C, Eckelman, Brendan P, Macedo, Chelsie, Jones, Kyle, Ma, Milton, Crago, William, Hollands, Andrew
Year of Publication 06.09.2022
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Year of Publication 06.09.2022
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Multivalent and Multispecific 41BB-Binding Proteins
Timmer, John C, Becklund, Bryan, Eckelman, Brendan P, Rascon, Lucas, Macedo, Chelsie, Jones, Kyle S, Razai, Amir S, Pandit, Rajay, Kaplan, Mike, Hussain, Abrahim, Deveraux, Quinn
Year of Publication 28.12.2023
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Year of Publication 28.12.2023
Patent
CD123-BINDING POLYPEPTIDES AND USES THEREOF
MACEDO, Chelsie, CRAGO, William, TIMMER, John C, JONES, Kyle, HOLLANDS, Andrew, MA, Milton, ECKELMAN, Brendan P
Year of Publication 16.03.2022
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Year of Publication 16.03.2022
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PDL1-binding proteins
Timmer, John C, Becklund, Bryan, Eckelman, Brendan P, Rascon, Lucas, Macedo, Chelsie, Jones, Kyle S, Razai, Amir S, Pandit, Rajay, Kaplan, Mike, Hussain, Abrahim, Deveraux, Quinn
Year of Publication 31.01.2023
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Year of Publication 31.01.2023
Patent
CD123-binding polypeptides and uses thereof
MACEDO, Chelsie, CRAGO, William, TIMMER, John C, JONES, Kyle, HOLLANDS, Andrew, MA, Milton, ECKELMAN, Brendan P
Year of Publication 11.11.2021
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Year of Publication 11.11.2021
Patent
CD123 TARGETED IMMUNOTHERAPIES
TIMMER, JOHN C, ECKELMAN, BRENDAN P, HOLLANDS, ANDREW, MA, MILTON, JARJOUR, JORDAN, MACEDO, CHELSIE, LEUNG, WAI-HANG, CRAGO, WILLIAM, JONES, KYLE, POGSON, MARK
Year of Publication 06.10.2022
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Year of Publication 06.10.2022
Patent
CD123-Binding Polypeptides and Uses Thereof
Timmer, John C, Eckelman, Brendan P, Macedo, Chelsie, Jones, Kyle, Ma, Milton, Crago, William, Hollands, Andrew
Year of Publication 05.11.2020
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Year of Publication 05.11.2020
Patent
Multivalent and Multispecific OX40-Binding Fusion Proteins
Timmer, John C, Becklund, Bryan, Eckelman, Brendan P, Rascon, Lucas, Macedo, Chelsie, Jones, Kyle S, Razai, Amir S, Pandit, Rajay, Kaplan, Mike, Hussain, Abrahim, Deveraux, Quinn
Year of Publication 07.04.2022
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Year of Publication 07.04.2022
Patent
CD123 TARGETED IMMUNOTHERAPIES
POGSON, Mark, MACEDO, Chelsie, JARJOUR, Jordan, CRAGO, William, LEUNG, Wai-Hang, TIMMER, John C, JONES, Kyle, HOLLANDS, Andrew, MA, Milton, ECKELMAN, Brendan P
Year of Publication 16.03.2022
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Year of Publication 16.03.2022
Patent
IMMUNOTHÉRAPIES CIBLANT CD123
MACEDO, Chelsie, POGSON, Mark, JARJOUR, Jordan, CRAGO, William, LEUNG, Wai-Hang, TIMMER, John C, ECKELMAN, Brendan P, HOLLANDS, Andrew, JONES, Kyle, MA, Milton
Year of Publication 16.03.2022
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Year of Publication 16.03.2022
Patent
CD123 targeted immunotherapies
POGSON, Mark, MACEDO, Chelsie, JARJOUR, Jordan, CRAGO, William, LEUNG, Wai-Hang, TIMMER, John C, JONES, Kyle, HOLLANDS, Andrew, MA, Milton, ECKELMAN, Brendan P
Year of Publication 06.01.2022
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Year of Publication 06.01.2022
Patent
CD123-BINDING POLYPEPTIDES AND USES THEREOF
TIMMER, JOHN C, ECKELMAN, BRENDAN P, HOLLANDS, ANDREW, MA, MILTON, MACEDO, CHELSIE, CRAGO, WILLIAM, JONES, KYLE
Year of Publication 12.11.2020
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Year of Publication 12.11.2020
Patent
CD123-BINDING POLYPEPTIDES AND USES THEREOF
MACEDO, Chelsie, CRAGO, William, TIMMER, John C, JONES, Kyle, HOLLANDS, Andrew, MA, Milton, ECKELMAN, Brendan P
Year of Publication 12.11.2020
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Year of Publication 12.11.2020
Patent
CD123 TARGETED IMMUNOTHERAPIES
POGSON, Mark, MACEDO, Chelsie, JARJOUR, Jordan, CRAGO, William, LEUNG, Wai-Hang, TIMMER, John C, JONES, Kyle, HOLLANDS, Andrew, MA, Milton, ECKELMAN, Brendan P
Year of Publication 12.11.2020
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Year of Publication 12.11.2020
Patent