Impact of high-throughput screening in biomedical research
Macarron, Ricardo, Banks, Martyn N, Bojanic, Dejan, Burns, David J, Cirovic, Dragan A, Garyantes, Tina, Green, Darren V. S, Hertzberg, Robert P, Janzen, William P, Paslay, Jeff W, Schopfer, Ulrich, Sittampalam, G. Sitta
Published in Nature reviews. Drug discovery (01.03.2011)
Published in Nature reviews. Drug discovery (01.03.2011)
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Book Review
Design and Implementation of High-Throughput Screening Assays
Powell, David J, Hertzberg, Robert P, Macarrόn, Ricardo
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2016)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2016)
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Nuisance Compounds, PAINS Filters, and Dark Chemical Matter in the GSK HTS Collection
Chakravorty, Subhas J., Chan, James, Greenwood, Marie Nicole, Popa-Burke, Ioana, Remlinger, Katja S., Pickett, Stephen D., Green, Darren V. S., Fillmore, Martin C., Dean, Tony W., Luengo, Juan I., Macarrón, Ricardo
Published in SLAS discovery (01.07.2018)
Published in SLAS discovery (01.07.2018)
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Identification of Novel Isoform-Selective Inhibitors within Class I Histone Deacetylases
Hu, Erding, Dul, Edward, Sung, Chiu-Mei, Chen, Zunxuan, Kirkpatrick, Robert, Zhang, Gui-Feng, Johanson, Kyung, Liu, Ronggang, Lago, Amparo, Hofmann, Glenn, Macarron, Ricardo, de los Frailes, Maite, Perez, Paloma, Krawiec, John, Winkler, James, Jaye, Michael
Published in The Journal of pharmacology and experimental therapeutics (01.11.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2003)
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Identification and Biological Characterization of Heterocyclic Inhibitors of the Hepatitis C Virus RNA-dependent RNA Polymerase
Dhanak, Dashyant, Duffy, Kevin J., Johnston, Victor K., Lin-Goerke, Juili, Darcy, Michael, Shaw, Antony N., Gu, Baohua, Silverman, Carol, Gates, Adam T., Nonnemacher, Michael R., Earnshaw, David L., Casper, David J., Kaura, Arun, Baker, Audrey, Greenwood, Cathy, Gutshall, Lester L., Maley, Derrick, DelVecchio, Alfred, Macarron, Ricardo, Hofmann, Glenn A., Alnoah, Zaid, Cheng, Hung-Yuan, Chan, George, Khandekar, Sanjay, Keenan, Richard M., Sarisky, Robert T.
Published in The Journal of biological chemistry (11.10.2002)
Published in The Journal of biological chemistry (11.10.2002)
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Design and implementation of high-throughput screening assays
Macarrón, Ricardo, Hertzberg, Robert P
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2009)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2009)
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Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2
Hummel, Joshua R., Xiao, Kai-Jiong, Yang, Jeffrey C., Epling, Leslie B., Mukai, Ken, Ye, Qinda, Xu, Meizhong, Qian, Dingquan, Huo, Lu, Weber, Michael, Roman, Valerie, Lo, Yvonne, Drake, Katherine, Stump, Kristine, Covington, Maryanne, Kapilashrami, Kanishk, Zhang, Guofeng, Ye, Min, Diamond, Sharon, Yeleswaram, Swamy, Macarron, Ricardo, Deller, Marc C., Wee, Susan, Kim, Sunkyu, Wang, Xiaozhao, Wu, Liangxing, Yao, Wenqing
Published in Journal of medicinal chemistry (22.02.2024)
Published in Journal of medicinal chemistry (22.02.2024)
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Highly efficient genome editing in primary human bronchial epithelial cells differentiated at air-liquid interface
Rapiteanu, Radu, Karagyozova, Tina, Zimmermann, Natalie, Singh, Kuljit, Wayne, Gareth, Martufi, Matteo, Belyaev, Nikolai N, Hessel, Edith M, Michalovich, David, Macarron, Ricardo, Rowan, Wendy C, Cairns, William J, Roger, Jan, Betts, Joanna, Beinke, Soren, Maratou, Klio
Published in The European respiratory journal (01.05.2020)
Published in The European respiratory journal (01.05.2020)
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Selective targeting of mutated calreticulin by the monoclonal antibody INCA033989 inhibits oncogenic function of MPN
Reis, Edimara S., Buonpane, Rebecca, Celik, Hamza, Marty, Caroline, Lei, Angela, Jobe, Fatoumata, Rupar, Mark, Zhang, Yue, DiMatteo, Darlise, Awdew, Rahel, Ferreira, Bianca L., Leffet, Lynn, Lu, Lu, Rosa, Elodie, Evrard, Maxime, Trivedi, Gaurang, Wass, Brittney, Horsey, April, He, Xin, Covington, Maryanne, Volgina, Alla, Pasquier, Florence, Legros, Laurence, Fouquet, Guillemette, Vainchenker, William, Yang, Yan-ou, Barker, Breann, Zhou, Jing, Stewart, Shaun, Hitchcock, Ian S., Dhanak, Dashyant, Macarron, Ricardo, Plo, Isabelle, Nastri, Horacio, Mayes, Patrick A.
Published in Blood (10.09.2024)
Published in Blood (10.09.2024)
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Abstract 412: Drug combination screen identifies pemigatinib, an FGFR inhibitor, as a mechanism to overcome KRASG12C inhibitor resistance in lung cancer
Abdollahi, Angela, Favata, Margaret, DiMatteo, Darlise, Schuette, Sean, Boarder, Erika, Rupar, Mark, Macarron, Ricardo, Gilmartin, Aidan, Wang, Hui, Amador-Arjona, Alejandro
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 5900: INCB161734: A novel, potent, and orally bioavailable KRAS G12D selective inhibitor demonstrates antitumor activity in KRAS G12D mutant tumors
Farren, Matthew R., Roman, Valerie, Gallion, Alexandra, Allali-Hassani, Abdellah, Sokolsky, Alexander, Kong, Weixi, Smith, Amanda, Wang, Hui, Correa, Gina, Deller, Marc, Epling, Leslie B., Procak, Jessica, Zhang, Guofeng, Pecko, Katherine, Kennedy, Keith, Boer, Jason, Kurzeja-Lipinski, Kerri, Covington, Maryanne, Chen, Kwang-Jong, Wallower, Renee, Rocha, Jennifer, Pan, Rina, Perry, Anthony, Yuska, Brad, Wang, Xiaozhao, Macarron, Ricardo, Kim, Sunkyu
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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