A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum
Beutler, Nathan, Pholcharee, Tossapol, Oyen, David, Flores-Garcia, Yevel, MacGill, Randall S, Garcia, Elijah, Calla, Jaeson, Parren, Mara, Yang, Linlin, Volkmuth, Wayne, Locke, Emily, Regules, Jason A, Dutta, Sheetij, Emerling, Daniel, Early, Angela M, Neafsey, Daniel E, Winzeler, Elizabeth A, King, C Richter, Zavala, Fidel, Burton, Dennis R, Wilson, Ian A, Rogers, Thomas F
Published in PLoS pathogens (01.03.2022)
Published in PLoS pathogens (01.03.2022)
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Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection
Martin, Gregory M., Torres, Jonathan L., Pholcharee, Tossapol, Oyen, David, Flores-Garcia, Yevel, Gibson, Grace, Moskovitz, Re’em, Beutler, Nathan, Jung, Diana D., Copps, Jeffrey, Lee, Wen-Hsin, Gonzalez-Paez, Gonzalo, Emerling, Daniel, MacGill, Randall S., Locke, Emily, King, C. Richter, Zavala, Fidel, Wilson, Ian A., Ward, Andrew B.
Published in Nature communications (28.07.2023)
Published in Nature communications (28.07.2023)
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Journal Article
Vaccination with synthetic long peptide formulated with CpG in an oil-in-water emulsion induces robust E7-specific CD8 T cell responses and TC-1 tumor eradication
Maynard, Sean K, Marshall, Jason D, MacGill, Randall S, Yu, Li, Cann, Jennifer A, Cheng, Lily I, McCarthy, Michael P, Cayatte, Corinne, Robbins, Scott H
Published in BMC cancer (06.06.2019)
Published in BMC cancer (06.06.2019)
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Analysis of Respiratory Syncytial Virus Preclinical and Clinical Variants Resistant to Neutralization by Monoclonal Antibodies Palivizumab and/or Motavizumab
Zhu, Qing, McAuliffe, Josie M., Patel, Nita K., Palmer-Hill, Frances J., Yang, Chin-fen, Liang, Brandon, Su, Lan, Zhu, Wei, Wachter, Leslie, Wilson, Susan, MacGill, Randall S., Krishnan, Subramaniam, McCarthy, Michael P., Losonsky, Genevieve A., Suzich, JoAnn A.
Published in The Journal of infectious diseases (01.03.2011)
Published in The Journal of infectious diseases (01.03.2011)
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Journal Article
GITR ligand fusion protein agonist enhances the tumor antigen-specific CD8 T-cell response and leads to long-lasting memory
Durham, Nick M, Holoweckyj, Nick, MacGill, Randall S, McGlinchey, Kelly, Leow, Ching Ching, Robbins, Scott H
Published in Journal for immunotherapy of cancer (20.06.2017)
Published in Journal for immunotherapy of cancer (20.06.2017)
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Establishing RTS,S/AS01 as a benchmark for comparison to next-generation malaria vaccines in a mouse model
Locke, Emily, Flores-Garcia, Yevel, Mayer, Bryan T., MacGill, Randall S., Borate, Bhavesh, Salgado-Jimenez, Berenice, Gerber, Monica W., Mathis-Torres, Shamika, Shapiro, Sarah, King, C. Richter, Zavala, Fidel
Published in npj vaccines (10.02.2024)
Published in npj vaccines (10.02.2024)
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Multiplex serological assay for establishing serological profiles of polymorphic, closely related peptide antigens
Bolton, Jessica, Chaudhury, Sidhartha, MacGill, Randall S., Early, Angela M., King, C. Richter, Locke, Emily, Neafsey, Daniel E., Bergmann-Leitner, Elke S.
Published in MethodsX (01.01.2021)
Published in MethodsX (01.01.2021)
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Complement Is Essential for Protection by an IgM and an IgG3 Monoclonal Antibody Against Experimental, Hematogenously Disseminated Candidiasis
Han, Yongmoon, Kozel, Thomas R, Zhang, Mason X, MacGill, Randall S, Carroll, Michael C, Cutler, Jim E
Published in The Journal of immunology (1950) (01.08.2001)
Published in The Journal of immunology (1950) (01.08.2001)
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Journal Article
Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses
McLeod, Brandon, Mabrouk, Moustafa T, Miura, Kazutoyo, Ravichandran, Rashmi, Kephart, Sally, Hailemariam, Sophia, Pham, Thao P, Semesi, Anthony, Kucharska, Iga, Kundu, Prasun, Huang, Wei-Chiao, Johnson, Max, Blackstone, Alyssa, Pettie, Deleah, Murphy, Michael, Kraft, John C, Leaf, Elizabeth M, Jiao, Yang, van de Vegte-Bolmer, Marga, van Gemert, Geert-Jan, Ramjith, Jordache, King, C Richter, MacGill, Randall S, Wu, Yimin, Lee, Kelly K, Jore, Matthijs M, King, Neil P, Lovell, Jonathan F, Julien, Jean-Philippe
Published in Immunity (Cambridge, Mass.) (13.09.2022)
Published in Immunity (Cambridge, Mass.) (13.09.2022)
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Journal Article
Breadth of humoral immune responses to the C-terminus of the circumsporozoite protein is associated with protective efficacy induced by the RTS,S malaria vaccine
Chaudhury, Sidhartha, MacGill, Randall S., Early, Angela M., Bolton, Jessica S., King, C. Richter, Locke, Emily, Pierson, Tony, Wirth, Dyann F., Neafsey, Daniel E., Bergmann-Leitner, Elke S.
Published in Vaccine (05.02.2021)
Published in Vaccine (05.02.2021)
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A candidate antibody drug for prevention of malaria
Williams, Katherine L., Guerrero, Steve, Flores-Garcia, Yevel, Kim, Dongkyoon, Williamson, Kevin S., Siska, Christine, Smidt, Pauline, Jepson, Sofia Z., Li, Kan, Dennison, S. Moses, Mathis-Torres, Shamika, Chen, Xiaomu, Wille-Reece, Ulrike, MacGill, Randall S., Walker, Michael, Jongert, Erik, King, C. Richter, Ockenhouse, Christian, Glanville, Jacob, Moon, James E., Regules, Jason A., Tan, Yann Chong, Cavet, Guy, Lippow, Shaun M., Robinson, William H., Dutta, Sheetij, Tomaras, Georgia D., Zavala, Fidel, Ketchem, Randal R., Emerling, Daniel E.
Published in Nature medicine (2024)
Published in Nature medicine (2024)
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Identification of broadly protective human antibodies to Pseudomonas aeruginosa exopolysaccharide Psl by phenotypic screening
DiGiandomenico, Antonio, Warrener, Paul, Hamilton, Melissa, Guillard, Sandrine, Ravn, Peter, Minter, Ralph, Camara, Maria Margarita, Venkatraman, Vignesh, Macgill, Randall S, Lin, Jia, Wang, Qun, Keller, Ashley Elaine, Bonnell, Jessica C, Tomich, Mladen, Jermutus, Lutz, McCarthy, Michael P, Melnick, David A, Suzich, Joann A, Stover, C Kendall
Published in The Journal of experimental medicine (02.07.2012)
Published in The Journal of experimental medicine (02.07.2012)
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Journal Article
Potent transmission-blocking monoclonal antibodies from naturally exposed individuals target a conserved epitope on Plasmodium falciparum Pfs230
Ivanochko, Danton, Fabra-García, Amanda, Teelen, Karina, van de Vegte-Bolmer, Marga, van Gemert, Geert-Jan, Newton, Jocelyn, Semesi, Anthony, de Bruijni, Marloes, Bolscher, Judith, Ramjith, Jordache, Szabat, Marta, Vogt, Stefanie, Kraft, Lucas, Duncan, Sherie, Lee, Shwu-Maan, Kamya, Moses R., Feeney, Margaret E., Jagannathan, Prasanna, Greenhouse, Bryan, Sauerwein, Robert W., Richter King, C., MacGill, Randall S., Bousema, Teun, Jore, Matthijs M., Julien, Jean-Philippe
Published in Immunity (Cambridge, Mass.) (14.02.2023)
Published in Immunity (Cambridge, Mass.) (14.02.2023)
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Biological Activities of Naturally Occurring Antibodies Reactive with Candida albicans Mannan
KOZEL, Thomas R, MACGILL, Randall S, PERCIVAL, Ann, ZHOU, Qing
Published in Infection and Immunity (01.01.2004)
Published in Infection and Immunity (01.01.2004)
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Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype
Barrett, Jordan R., Pipini, Dimitra, Wright, Nathan D., Cooper, Andrew J.R., Gorini, Giacomo, Quinkert, Doris, Lias, Amelia M., Davies, Hannah, Rigby, Cassandra A., Aleshnick, Maya, Williams, Barnabas G., Bradshaw, William J., Paterson, Neil G., Martinson, Thomas, Kirtley, Payton, Picard, Luc, Wiggins, Christine D., Donnellan, Francesca R., King, Lloyd D.W., Wang, Lawrence T., Popplewell, Jonathan F., Silk, Sarah E., de Ruiter Swain, Jed, Skinner, Katherine, Kotraiah, Vinayaka, Noe, Amy R., MacGill, Randall S., King, C. Richter, Birkett, Ashley J., Soisson, Lorraine A., Minassian, Angela M., Lauffenburger, Douglas A., Miura, Kazutoyo, Long, Carole A., Wilder, Brandon K., Koekemoer, Lizbé, Tan, Joshua, Nielsen, Carolyn M., McHugh, Kirsty, Draper, Simon J.
Published in Cell (05.09.2024)
Published in Cell (05.09.2024)
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Journal Article
Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoes
Fabra-García, Amanda, Hailemariam, Sophia, de Jong, Roos M., Janssen, Kirsten, Teelen, Karina, van de Vegte-Bolmer, Marga, van Gemert, Geert-Jan, Ivanochko, Danton, Semesi, Anthony, McLeod, Brandon, Vos, Martijn W., de Bruijni, Marloes H.C., Bolscher, Judith M., Szabat, Marta, Vogt, Stefanie, Kraft, Lucas, Duncan, Sherie, Kamya, Moses R., Feeney, Margaret E., Jagannathan, Prasanna, Greenhouse, Bryan, Dechering, Koen J., Sauerwein, Robert W., King, C. Richter, MacGill, Randall S., Bousema, Teun, Julien, Jean-Philippe, Jore, Matthijs M.
Published in Immunity (Cambridge, Mass.) (14.02.2023)
Published in Immunity (Cambridge, Mass.) (14.02.2023)
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Journal Article
Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex
Williams, Barnabas G., King, Lloyd D. W., Pulido, David, Quinkert, Doris, Lias, Amelia M., Silk, Sarah E., Ragotte, Robert J., Davies, Hannah, Barrett, Jordan R., McHugh, Kirsty, Rigby, Cassandra A., Alanine, Daniel G. W., Barfod, Lea, Shea, Michael W., Cowley, Li An, Dabbs, Rebecca A., Pattinson, David J., Douglas, Alexander D., Lyth, Oliver R., Illingworth, Joseph J., Jin, Jing, Carnrot, Cecilia, Kotraiah, Vinayaka, Christen, Jayne M., Noe, Amy R., MacGill, Randall S., King, C. Richter, Birkett, Ashley J., Soisson, Lorraine A., Skinner, Katherine, Miura, Kazutoyo, Long, Carole A., Higgins, Matthew K., Draper, Simon J.
Published in Nature communications (07.06.2024)
Published in Nature communications (07.06.2024)
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Journal Article
Preclinical development of a stabilized RH5 virus-like particle vaccine that induces improved antimalarial antibodies
King, Lloyd D.W., Pulido, David, Barrett, Jordan R., Davies, Hannah, Quinkert, Doris, Lias, Amelia M., Silk, Sarah E., Pattinson, David J., Diouf, Ababacar, Williams, Barnabas G., McHugh, Kirsty, Rodrigues, Ana, Rigby, Cassandra A., Strazza, Veronica, Suurbaar, Jonathan, Rees-Spear, Chloe, Dabbs, Rebecca A., Ishizuka, Andrew S., Zhou, Yu, Gupta, Gaurav, Jin, Jing, Li, Yuanyuan, Carnrot, Cecilia, Minassian, Angela M., Campeotto, Ivan, Fleishman, Sarel J., Noe, Amy R., MacGill, Randall S., King, C. Richter, Birkett, Ashley J., Soisson, Lorraine A., Long, Carole A., Miura, Kazutoyo, Ashfield, Rebecca, Skinner, Katherine, Howarth, Mark R., Biswas, Sumi, Draper, Simon J.
Published in Cell reports. Medicine (16.07.2024)
Published in Cell reports. Medicine (16.07.2024)
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