The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals
Torrence, Margaret E, MacArthur, Michael R, Hosios, Aaron M, Valvezan, Alexander J, Asara, John M, Mitchell, James R, Manning, Brendan D
Published in eLife (01.03.2021)
Published in eLife (01.03.2021)
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Journal Article
Optimizing preclinical models of ageing for translation to clinical trials
Mitchell, Sarah J., MacArthur, Michael R., Kane, Alice E.
Published in British journal of clinical pharmacology (21.09.2023)
Published in British journal of clinical pharmacology (21.09.2023)
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Journal Article
Age and life expectancy clocks based on machine learning analysis of mouse frailty
Schultz, Michael B, Kane, Alice E, Mitchell, Sarah J, MacArthur, Michael R, Warner, Elisa, Vogel, David S, Mitchell, James R, Howlett, Susan E, Bonkowski, Michael S, Sinclair, David A
Published in Nature communications (15.09.2020)
Published in Nature communications (15.09.2020)
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Journal Article
Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses
Langston, P Kent, Nambu, Aya, Jung, Jonathan, Shibata, Munehiko, Aksoylar, H Ibrahim, Lei, Jiahui, Xu, Peining, Doan, Mary T, Jiang, Helen, MacArthur, Michael R, Gao, Xia, Kong, Yong, Chouchani, Edward T, Locasale, Jason W, Snyder, Nathaniel W, Horng, Tiffany
Published in Nature immunology (01.09.2019)
Published in Nature immunology (01.09.2019)
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Journal Article
Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H2S Production
Longchamp, Alban, Mirabella, Teodelinda, Arduini, Alessandro, MacArthur, Michael R., Das, Abhirup, Treviño-Villarreal, J. Humberto, Hine, Christopher, Ben-Sahra, Issam, Knudsen, Nelson H., Brace, Lear E., Reynolds, Justin, Mejia, Pedro, Tao, Ming, Sharma, Gaurav, Wang, Rui, Corpataux, Jean-Marc, Haefliger, Jacques-Antoine, Ahn, Kyo Han, Lee, Chih-Hao, Manning, Brendan D., Sinclair, David A., Chen, Christopher S., Ozaki, C. Keith, Mitchell, James R.
Published in Cell (22.03.2018)
Published in Cell (22.03.2018)
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Journal Article
Interferon-α2b Treatment for COVID-19 Is Associated with Improvements in Lung Abnormalities
Zhou, Qiong, MacArthur, Michael R, He, Xinliang, Wei, Xiaoshan, Zarin, Payam, Hanna, Bola S, Wang, Zi-Hao, Xiang, Xuan, Fish, Eleanor N
Published in Viruses (30.12.2020)
Published in Viruses (30.12.2020)
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Journal Article
Calpain Inhibition Protects against UVB-Induced Degradation of Dermal–Epidermal Junction–Associated Proteins
Doleckova, Iva, Vidovic, Tinka, Jandova, Lenka, Gretzmeier, Christine, Navarini, Alexander A., MacArthur, Michael R., Goksel, Orcun, Nyström, Alexander, Ewald, Collin Y.
Published in Journal of investigative dermatology (01.09.2024)
Published in Journal of investigative dermatology (01.09.2024)
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Journal Article
Total protein, not amino acid composition, differs in plant-based versus omnivorous dietary patterns and determines metabolic health effects in mice
MacArthur, Michael R., Mitchell, Sarah J., Treviño-Villarreal, J. Humberto, Grondin, Yohann, Reynolds, Justin S., Kip, Peter, Jung, Jonathan, Trocha, Kaspar M., Ozaki, C. Keith, Mitchell, James R.
Published in Cell metabolism (07.09.2021)
Published in Cell metabolism (07.09.2021)
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Journal Article
Gut Microbiota Predicts Healthy Late-Life Aging in Male Mice
Ke, Shanlin, Mitchell, Sarah J, MacArthur, Michael R, Kane, Alice E, Sinclair, David A, Venable, Emily M, Chadaideh, Katia S, Carmody, Rachel N, Grodstein, Francine, Mitchell, James R, Liu, Yangyu
Published in Nutrients (21.09.2021)
Published in Nutrients (21.09.2021)
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Journal Article
The mitochondrial DNA common deletion as a potential biomarker of cancer-associated fibroblasts from skin basal and squamous cell carcinomas
Fontana, Gabriele A, MacArthur, Michael R, Rotankova, Nadezhda, Di Filippo, Michela, Beer, Hans-Dietmar, Gahlon, Hailey L
Published in Scientific reports (04.01.2024)
Published in Scientific reports (04.01.2024)
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Journal Article
Intracellular H2S production is an autophagy-dependent adaptive response to DNA damage
Jiang, Xiaofeng, MacArthur, Michael R., Treviño-Villarreal, J. Humberto, Kip, Peter, Ozaki, C. Keith, Mitchell, Sarah J., Mitchell, James R.
Published in Cell chemical biology (16.12.2021)
Published in Cell chemical biology (16.12.2021)
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Journal Article
Short-term hypercaloric carbohydrate loading increases surgical stress resilience by inducing FGF21
Agius, Thomas, Emsley, Raffaella, Lyon, Arnaud, MacArthur, Michael R, Kiesworo, Kevin, Faivre, Anna, Stavart, Louis, Lambelet, Martine, Legouis, David, de Seigneux, Sophie, Golshayan, Déla, Lazeyras, Francois, Yeh, Heidi, Markmann, James F, Uygun, Korkut, Ocampo, Alejandro, Mitchell, Sarah J, Allagnat, Florent, Déglise, Sébastien, Longchamp, Alban
Published in Nature communications (05.02.2024)
Published in Nature communications (05.02.2024)
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Journal Article
Supporting employers and their employees with Mental hEalth problems to remain eNgaged and producTive at wORk (MENTOR): A feasibility randomised controlled trial protocol
Prudenzi, Arianna, Jadhakhan, Feroz, Gill, Kiranpreet, MacArthur, Michael, Patel, Krishane, Moukhtarian, Talar, Kershaw, Charlotte, Norton-Brown, Errin, Johnston, Naomi, Daly, Guy, Russell, Sean, Thomson, Louise, Munir, Fehmidah, Blake, Holly, Meyer, Caroline, Marwaha, Steven
Published in PloS one (20.04.2023)
Published in PloS one (20.04.2023)
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Journal Article
The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth
Schrötter, Sandra, Yuskaitis, Christopher J., MacArthur, Michael R., Mitchell, Sarah J., Hosios, Aaron M., Osipovich, Maria, Torrence, Margaret E., Mitchell, James R., Hoxhaj, Gerta, Sahin, Mustafa, Manning, Brendan D.
Published in Cell reports (Cambridge) (17.05.2022)
Published in Cell reports (Cambridge) (17.05.2022)
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Journal Article
Sodium thiosulfate acts as a hydrogen sulfide mimetic to prevent intimal hyperplasia via inhibition of tubulin polymerisation
Macabrey, Diane, Longchamp, Alban, MacArthur, Michael R., Lambelet, Martine, Urfer, Severine, Deglise, Sebastien, Allagnat, Florent
Published in EBioMedicine (01.04.2022)
Published in EBioMedicine (01.04.2022)
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Journal Article
Short-term preoperative protein restriction attenuates vein graft disease via induction of cystathionine γ-lyase
Trocha, Kaspar M, Kip, Peter, Tao, Ming, MacArthur, Michael R, Treviño-Villarreal, J Humberto, Longchamp, Alban, Toussaint, Wendy, Lambrecht, Bart N, de Vries, Margreet R, Quax, Paul H A, Mitchell, James R, Ozaki, C Keith
Published in Cardiovascular research (01.02.2020)
Published in Cardiovascular research (01.02.2020)
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