Dual Inhibition of PI3K/AKT and MEK/ERK Pathways Induces Synergistic Antitumor Effects in Diffuse Intrinsic Pontine Glioma Cells
Wu, Y. Linda, Maachani, Uday Bhanu, Schweitzer, Melanie, Singh, Ranjodh, Wang, Melinda, Chang, Raymond, Souweidane, Mark M
Published in Translational oncology (01.04.2017)
Published in Translational oncology (01.04.2017)
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Utility of multimodality molecular profiling for pediatric patients with central nervous system tumors
Rajappa, Prajwal, Eng, Kenneth W, Bareja, Rohan, Bander, Evan D, Yuan, Melissa, Dua, Alisha, Bhanu Maachani, Uday, Snuderl, Matija, Pan, Heng, Zhang, Tuo, Tosi, Umberto, Ivasyk, Iryna, Souweidane, Mark M, Elemento, Olivier, Sboner, Andreas, Greenfield, Jeffrey P, Pisapia, David J
Published in Neuro-oncology advances (01.01.2022)
Published in Neuro-oncology advances (01.01.2022)
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Molecular profiling of MPS1 gene silencing in U251 glioma cell line
Shankavaram, Uma, Maachani, Uday Bhanu, Zhao, Shuping, Camphausen, Kevin, Tandle, Anita
Published in Genomics data (01.12.2015)
Published in Genomics data (01.12.2015)
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Targeting MPS1 Enhances Radiosensitization of Human Glioblastoma by Modulating DNA Repair Proteins
Maachani, Uday Bhanu, Kramp, Tamalee, Hanson, Ryan, Zhao, Shuping, Celiku, Orieta, Shankavaram, Uma, Colombo, Riccardo, Caplen, Natasha J, Camphausen, Kevin, Tandle, Anita
Published in Molecular cancer research (01.05.2015)
Published in Molecular cancer research (01.05.2015)
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PDTM-26. DUAL THERAPY WITH PI3K INHIBITOR ZSTK-474 AND MEK INHIBITOR TRAMETINIB VIA CONVECTION-ENHANCED DELIVERY IN A GENETICALLY-ENGINEERED MOUSE MODEL OF DIFFUSE INTRINSIC PONTINE GLIOMA
Chang, Raymond, Tosi, Umberto, Bhanu Maachani, Uday, Voronina, Iuliia, Schweitzer, Melanie, Wu, Linda, Souweidane, Mark
Published in Neuro-oncology (Charlottesville, Va.) (05.11.2018)
Published in Neuro-oncology (Charlottesville, Va.) (05.11.2018)
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EXTH-55. PET, IMAGE-GUIDED HDAC INHIBITION OF PEDIATRIC DIFFUSE MIDLINE GLIOMA IMPROVES SURVIVAL IN MURINE MODELS
Tosi, Umberto, Kommidi, Harikrishna, Adeuyan, Oluwaseyi, Guo, Hua, Maachani, Uday Bhanu, Chen, Nandi, Su, Taojunfeng, Zhang, Guoan, Pisapia, David, Dahmane, Nadia, Ting, Richard, Souweidane, Mark
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
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TBIO-06. B7-H3 EXPRESSION AS A POTENTIAL BIOMARKER OF PROGNOSIS AND TARGET IN PEDIATRIC GLIAL AND NON-GLIAL CNS TUMORS
Maachani, Uday Bhanu, Zhou, Zhiping, Martinez, Daniel, Santi, Mariarita, Dahmane, Nadia, Souweidane, Mark
Published in Neuro-oncology (Charlottesville, Va.) (22.06.2018)
Published in Neuro-oncology (Charlottesville, Va.) (22.06.2018)
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PDTM-47. REAL TIME IN VIVO MONITORING OF 18F-LABELED PANOBINOSTAT PHARMAKOKINETICS FOR TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) VIA CONVECTION ENHANCED DELIVERY (CED)
Tosi, Umberto, Kommidi, Harikrishna, Bhanu Maachani, Uday, Marnell, Christopher, Guo, Hua, Schweitzer, Melanie, Ting, Richard, Souweidane, Mark
Published in Neuro-oncology (Charlottesville, Va.) (05.11.2018)
Published in Neuro-oncology (Charlottesville, Va.) (05.11.2018)
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HGG-04. A HIGH-THROUGHPUT IN VITRO DRUG SCREEN OF PATIENT-DERIVED GLIOMATOSIS CEREBRI CELLS FOR PRECISION MEDICINE
Maachani, Uday Bhanu, Rajappa, Prajwal, Voronina, Julia C., Souweidane, Mark M., Greenfield, Jeffrey P.
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2017)
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2017)
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Abstract 190: Modulation of MiR-21 signaling by MPS1 in human glioblastoma
Maachani, Uday Bhanu, Tandle, Anita, Shankavaram, Uma, Kramp, Tamalee, Camphausen, Kevin A.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Abstract 2986: Targeting multiple nodes in the RTK- PI3KAKTmTOR signaling pathway in a p53-- mouse model of DIPG induces G2M phase cell cycle arrest
Wu, Yue Linda, Maachani, Uday Bhanu, Schweitzer, Melanie, Becher, Oren J, Wang, Melinda, Singh, Ranjodh, Zhou, Zhiping, Souweidane, Mark M
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 2986: Targeting multiple nodes in the RTK- PI3K/AKT/mTOR signaling pathway in a p53-/- mouse model of DIPG induces G2/M phase cell cycle arrest
Wu, Yue Linda, Maachani, Uday Bhanu, Schweitzer, Melanie, Becher, Oren J., Wang, Melinda, Singh, Ranjodh, Zhou, Zhiping, Souweidane, Mark M.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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PET, image-guided HDAC inhibition of pediatric diffuse midline glioma improves survival in murine models
Tosi, Umberto, Kommidi, Harikrishna, Adeuyan, Oluwaseyi, Guo, Hua, Maachani, Uday Bhanu, Chen, Nandi, Su, Taojunfeng, Zhang, Guoan, Pisapia, David J, Dahmane, Nadia, Ting, Richard, Souweidane, Mark M
Published in Science advances (01.07.2020)
Published in Science advances (01.07.2020)
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HG-05DIFFERENTIAL EXPRESSION OF PARP1/2 AS A BIOMARKER OF DIPG MALIGNANT PROGRESSION: RELATIONSHIP TO TGF-β/BMP SIGNALING AND EZH2 GLOBAL METHYLATION
Maachani, Uday Bhanu, Shankavaram, Uma, Schweitzer, Melanie, Wu, Yue Linda, Camphausen, Kevin, Souweidane, Mark
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2016)
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2016)
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DIPG-20. THE DEVELOPMENT OF THERANOSTIC [18F]F2B-CONJUGATES FOR PHARMACOKINETIC MONITORING OF DIRECT DRUG DELIVERY
Tosi, Umberto, Kommidi, Hari Krishna, Marnell, Christopher, Guo, Sarah, Schweitzer, Melanie, Voronina, Julia, Maachani, Uday Bhanu, Ting, Richard, Souweidane, Mark
Published in Neuro-oncology (Charlottesville, Va.) (31.05.2017)
Published in Neuro-oncology (Charlottesville, Va.) (31.05.2017)
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Abstract 849: Profiling signaling networks using reverse phase protein arrays: validating FOXM1 as a potential target to radiosensitize glioblastoma (GBM) stem cells
Maachani, Uday Bhanu, Tandle, Anita T., Shankavaram, Uma, Meushaw, Tamalee, Tofilon, Philip J., Camphausen, Kevin A.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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TRTH-04. POTENTIAL OF NANO-FIBER PEPTIDE (NFP)-CONJUGATED THERAPEUTICS FOR LOCAL CONVECTION-ENHANCED DELIVERY (CED) IN CNS TUMORS
Tosi, Umberto, Bellat, Vanessa, Kommidi, Hari Krishna, Schweitzer, Melanie, Guo, Sarah, Marnell, Christopher, Maachani, Uday Bhanu, Ting, Richard, Law, Benedict, Souweidane, Mark
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2017)
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2017)
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Journal Article
Dual Inhibition of PI3K/AKT and MEK/ERK Pathways Induces Synergistic Antitumor Effects in Diffuse Intrinsic Pontine Glioma Cells1
Wu, Y. Linda, Maachani, Uday Bhanu, Schweitzer, Melanie, Singh, Ranjodh, Wang, Melinda, Chang, Raymond, Souweidane, Mark M.
Published in Translational oncology (09.02.2017)
Published in Translational oncology (09.02.2017)
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DIPG-20. THE DEVELOPMENT OF THERANOSTIC [18F]F2B-CONJUGATES FOR PHARMACOKINETIC MONITORING OF DIRECT DRUG DELIVERY
Tosi, Umberto, Kommidi, Hari Krishna, Marnell, Christopher, Guo, Sarah, Schweitzer, Melanie, Voronina, Julia, Maachani, Uday Bhanu, Ting, Richard, Souweidane, Mark
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2017)
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2017)
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