Potent 3‐Hydroxy‐2‐Pyridine Aldoxime Reactivators of Organophosphate‐Inhibited Cholinesterases with Predicted Blood–Brain Barrier Penetration
Zorbaz, Tamara, Braïki, Anissa, Maraković, Nikola, Renou, Julien, de la Mora, Eugenio, Maček Hrvat, Nikolina, Katalinić, Maja, Silman, Israel, Sussman, Joel L., Mercey, Guillaume, Gomez, Catherine, Mougeot, Romain, Pérez, Belén, Baati, Rachid, Nachon, Florian, Weik, Martin, Jean, Ludovic, Kovarik, Zrinka, Renard, Pierre‐Yves
Published in Chemistry : a European journal (05.07.2018)
Published in Chemistry : a European journal (05.07.2018)
Get full text
Journal Article
Pyridinium Oximes with Ortho-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase Inhibited by Several Nerve Agents
Zorbaz, Tamara, Malinak, David, Maraković, Nikola, Maček Hrvat, Nikolina, Zandona, Antonio, Novotny, Michal, Skarka, Adam, Andrys, Rudolf, Benkova, Marketa, Soukup, Ondrej, Katalinić, Maja, Kuca, Kamil, Kovarik, Zrinka, Musilek, Kamil
Published in Journal of medicinal chemistry (13.12.2018)
Published in Journal of medicinal chemistry (13.12.2018)
Get full text
Journal Article
Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases
Maček Hrvat, Nikolina, Kalisiak, Jarosław, Šinko, Goran, Radić, Zoran, Sharpless, K. Barry, Taylor, Palmer, Kovarik, Zrinka
Published in Toxicology letters (15.03.2020)
Published in Toxicology letters (15.03.2020)
Get full text
Journal Article
Reversal of Tabun Toxicity Enabled by a Triazole‐Annulated Oxime Library—Reactivators of Acetylcholinesterase
Kovarik, Zrinka, Kalisiak, Jarosław, Hrvat, Nikolina Maček, Katalinić, Maja, Zorbaz, Tamara, Žunec, Suzana, Green, Carol, Radić, Zoran, Fokin, Valery V., Sharpless, K. Barry, Taylor, Palmer
Published in Chemistry : a European journal (15.03.2019)
Published in Chemistry : a European journal (15.03.2019)
Get full text
Journal Article
Catalytic Soman Scavenging by the Y337A/F338A Acetylcholinesterase Mutant Assisted with Novel Site-Directed Aldoximes
Kovarik, Zrinka, Maček Hrvat, Nikolina, Katalinić, Maja, Sit, Rakesh K, Paradyse, Alexander, Žunec, Suzana, Musilek, Kamil, Fokin, Valery V, Taylor, Palmer, Radić, Zoran
Published in Chemical research in toxicology (18.05.2015)
Published in Chemical research in toxicology (18.05.2015)
Get full text
Journal Article
Who's in, who's out? Re‐evaluation of lipid raft residents
Mlinac‐Jerkovic, Kristina, Ilic, Katarina, Zjalić, Milorad, Mandić, Dario, Debeljak, Željko, Balog, Marta, Damjanović, Vladimir, Maček Hrvat, Nikolina, Habek, Nikola, Kalanj‐Bognar, Svjetlana, Schnaar, Ronald L., Heffer, Marija
Published in Journal of neurochemistry (01.08.2021)
Published in Journal of neurochemistry (01.08.2021)
Get full text
Journal Article
A comprehensive evaluation of novel oximes in creation of butyrylcholinesterase-based nerve agent bioscavengers
Katalinić, Maja, Maček Hrvat, Nikolina, Baumann, Krešimir, Morasi Piperčić, Sara, Makarić, Sandro, Tomić, Srđanka, Jović, Ozren, Hrenar, Tomica, Miličević, Ante, Jelić, Dubravko, Žunec, Suzana, Primožič, Ines, Kovarik, Zrinka
Published in Toxicology and applied pharmacology (01.11.2016)
Published in Toxicology and applied pharmacology (01.11.2016)
Get full text
Journal Article
Design, synthesis and cholinesterase inhibitory properties of new oxazole benzylamine derivatives
Šagud, Ivana, Maček Hrvat, Nikolina, Grgičević, Ana, Čadež, Tena, Hodak, Josipa, Dragojević, Milena, Lasić, Kornelija, Kovarik, Zrinka, Škorić, Irena
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
Get full text
Journal Article
Pharmacokinetic Evaluation of Brain Penetrating Morpholine-3-hydroxy-2-pyridine Oxime as an Antidote for Nerve Agent Poisoning
Zorbaz, Tamara, Mišetić, Petra, Probst, Nicolas, Žunec, Suzana, Zandona, Antonio, Mendaš, Gordana, Micek, Vedran, Maček Hrvat, Nikolina, Katalinić, Maja, Braïki, Anissa, Jean, Ludovic, Renard, Pierre-Yves, Gabelica Marković, Vesna, Kovarik, Zrinka
Published in ACS chemical neuroscience (01.04.2020)
Published in ACS chemical neuroscience (01.04.2020)
Get full text
Journal Article
Counteracting poisoning with chemical warfare nerve agents
Hrvat, Nikolina Maček, Kovarik, Zrinka
Published in Arhiv za higijenu rada i toksikologiju (01.12.2020)
Published in Arhiv za higijenu rada i toksikologiju (01.12.2020)
Get full text
Journal Article
Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure
Sit, Rakesh K, Kovarik, Zrinka, Maček Hrvat, Nikolina, Žunec, Suzana, Green, Carol, Fokin, Valery V, Sharpless, K Barry, Radić, Zoran, Taylor, Palmer
Published in The Journal of pharmacology and experimental therapeutics (01.11.2018)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2018)
Get full text
Journal Article
Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents
Zorbaz, Tamara, Malinak, David, Hofmanova, Tereza, Maraković, Nikola, Žunec, Suzana, Hrvat, Nikolina Maček, Andrys, Rudolf, Psotka, Miroslav, Zandona, Antonio, Svobodova, Jana, Prchal, Lukas, Fingler, Sanja, Katalinić, Maja, Kovarik, Zrinka, Musilek, Kamil
Published in European journal of medicinal chemistry (05.08.2022)
Published in European journal of medicinal chemistry (05.08.2022)
Get full text
Journal Article
Redistribution of gangliosides accompanies thermally induced Na+, K+-ATPase activity alternation and submembrane localisation in mouse brain
Puljko, Borna, Stojanović, Mario, Ilic, Katarina, Maček Hrvat, Nikolina, Zovko, Ana, Damjanović, Vladimir, Mlinac-Jerkovic, Kristina, Kalanj-Bognar, Svjetlana
Published in Biochimica et biophysica acta. Biomembranes (01.01.2021)
Published in Biochimica et biophysica acta. Biomembranes (01.01.2021)
Get full text
Journal Article