Mosaic expression of claudins in thick ascending limbs of Henle results in spatial separation of paracellular Na⁺ and Mg2+ transport
Milatz, Susanne, Himmerkus, Nina, Wulfmeyer, Vera Christine, Drewell, Hoora, Mutig, Kerim, Hou, Jianghui, Breiderhoff, Tilman, Müller, Dominik, Fromm, Michael, Bleich, Markus, Günzel, Dorothee
Published in Proceedings of the National Academy of Sciences - PNAS (10.01.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (10.01.2017)
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Journal Article
AMP-activated kinase is a regulator of fibroblast growth factor 23 production
Glosse, Philipp, Feger, Martina, Mutig, Kerim, Chen, Hong, Hirche, Frank, Hasan, Ahmed Abdallah, Gaballa, Mohamed M.S., Hocher, Berthold, Lang, Florian, Föller, Michael
Published in Kidney international (01.09.2018)
Published in Kidney international (01.09.2018)
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Journal Article
WNK1-related Familial Hyperkalemic Hypertension results from an increased expression of L-WNK1 specifically in the distal nephron
Vidal-Petiot, Emmanuelle, Elvira-Matelot, Emilie, Mutig, Kerim, Soukaseum, Christelle, Baudrie, Véronique, Wu, Shengnan, Cheval, Lydie, Huc, Elizabeth, Cambillau, Michèle, Bachmann, Sebastian, Doucet, Alain, Jeunemaitre, Xavier, Hadchouel, Juliette
Published in Proceedings of the National Academy of Sciences - PNAS (27.08.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (27.08.2013)
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Journal Article
Combination of immune checkpoint inhibitors with radiation therapy in cancer: A hammer breaking the wall of resistance
Voronova, Veronika, Vislobokova, Anastasia, Mutig, Kerim, Samsonov, Mikhail, Peskov, Kirill, Sekacheva, Marina, Materenchuk, Maria, Bunyatyan, Natalya, Lebedeva, Svetlana
Published in Frontiers in oncology (05.12.2022)
Published in Frontiers in oncology (05.12.2022)
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Journal Article
Deletion of claudin-10 (Cldn10) in the thick ascending limb impairs paracellular sodium permeability and leads to hypermagnesemia and nephrocalcinosis
Breiderhoff, Tilman, Himmerkus, Nina, Stuiver, Marchel, Mutig, Kerim, Will, Constanze, Meij, Iwan C, Bachmann, Sebastian, Bleich, Markus, Willnow, Thomas E, Müller, Dominik
Published in Proceedings of the National Academy of Sciences - PNAS (28.08.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (28.08.2012)
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Journal Article
A SPAK Isoform Switch Modulates Renal Salt Transport and Blood Pressure
McCormick, James A., Mutig, Kerim, Nelson, Joshua H., Saritas, Turgay, Hoorn, Ewout J., Yang, Chao-Ling, Rogers, Shaunessy, Curry, Joshua, Delpire, Eric, Bachmann, Sebastian, Ellison, David H.
Published in Cell metabolism (07.09.2011)
Published in Cell metabolism (07.09.2011)
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Journal Article
Activation of the Bumetanide-sensitive Na+,K+,2Cl− Cotransporter (NKCC2) Is Facilitated by Tamm-Horsfall Protein in a Chloride-sensitive Manner
Mutig, Kerim, Kahl, Thomas, Saritas, Turgay, Godes, Michael, Persson, Pontus, Bates, James, Raffi, Hajamohideen, Rampoldi, Luca, Uchida, Shinichi, Hille, Carsten, Dosche, Carsten, Kumar, Satish, Castañeda-Bueno, Maria, Gamba, Gerardo, Bachmann, Sebastian
Published in The Journal of biological chemistry (26.08.2011)
Published in The Journal of biological chemistry (26.08.2011)
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Journal Article
Claudin-10a Deficiency Shifts Proximal Tubular Cl - Permeability to Cation Selectivity via Claudin-2 Redistribution
Breiderhoff, Tilman, Himmerkus, Nina, Meoli, Luca, Fromm, Anja, Sewerin, Sebastian, Kriuchkova, Natalia, Nagel, Oliver, Ladilov, Yury, Krug, Susanne M, Quintanova, Catarina, Stumpp, Meike, Garbe-Schönberg, Dieter, Westernströer, Ulrike, Merkel, Cosima, Brinkhus, Merle Annette, Altmüller, Janine, Schweiger, Michal R, Müller, Dominik, Mutig, Kerim, Morawski, Markus, Halbritter, Jan, Milatz, Susanne, Bleich, Markus, Günzel, Dorothee
Published in Journal of the American Society of Nephrology (01.04.2022)
Published in Journal of the American Society of Nephrology (01.04.2022)
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Journal Article
Metabolic effects of vasopressin in pathophysiology of diabetic kidney disease
Lebedeva, Svetlana, Margaryan, Arus, Smolyarchuk, Elena, Nedorubov, Andrey, Materenchuk, Maria, Tonevitsky, Alexander, Mutig, Kerim
Published in Frontiers in endocrinology (Lausanne) (18.09.2023)
Published in Frontiers in endocrinology (Lausanne) (18.09.2023)
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Journal Article
Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3
McCormick, James A, Yang, Chao-Ling, Zhang, Chong, Davidge, Brittney, Blankenstein, Katharina I, Terker, Andrew S, Yarbrough, Bethzaida, Meermeier, Nicholas P, Park, Hae J, McCully, Belinda, West, Mark, Borschewski, Aljona, Himmerkus, Nina, Bleich, Markus, Bachmann, Sebastian, Mutig, Kerim, Argaiz, Eduardo R, Gamba, Gerardo, Singer, Jeffrey D, Ellison, David H
Published in The Journal of clinical investigation (01.11.2014)
Published in The Journal of clinical investigation (01.11.2014)
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Journal Article
Vasopressin Increases Urinary Acidification via V1a Receptors in Collecting Duct Intercalated Cells
Giesecke, Torsten, Himmerkus, Nina, Leipziger, Jens, Bleich, Markus, Koshimizu, Taka-Aki, Fähling, Michael, Smorodchenko, Alina, Shpak, Julia, Knappe, Carolin, Isermann, Julian, Ayasse, Niklas, Kawahara, Katsumasa, Schmoranzer, Jan, Gimber, Niclas, Paliege, Alexander, Bachmann, Sebastian, Mutig, Kerim
Published in Journal of the American Society of Nephrology (01.06.2019)
Published in Journal of the American Society of Nephrology (01.06.2019)
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Journal Article
Renal Deletion of 12 kDa FK506-Binding Protein Attenuates Tacrolimus-Induced Hypertension
Lazelle, Rebecca A, McCully, Belinda H, Terker, Andrew S, Himmerkus, Nina, Blankenstein, Katharina I, Mutig, Kerim, Bleich, Markus, Bachmann, Sebastian, Yang, Chao-Ling, Ellison, David H
Published in Journal of the American Society of Nephrology (01.05.2016)
Published in Journal of the American Society of Nephrology (01.05.2016)
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Journal Article
SPAK Differentially Mediates Vasopressin Effects on Sodium Cotransporters
SARITAS, Turgay, BORSCHEWSKI, Aljona, LAGHMANI, Kamel, DELPIRE, Eric, ELLISON, David H, BACHMANN, Sebastian, MUTIG, Kerim, MCCORMICK, James A, PALIEGE, Alexander, DATHE, Christin, UCHIDA, Shinichi, TERKER, Andrew, HIMMERKUS, Nina, BLEICH, Markus, DEMARETZ, Sylvie
Published in Journal of the American Society of Nephrology (01.03.2013)
Published in Journal of the American Society of Nephrology (01.03.2013)
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Journal Article
Reciprocal Regulation of Aquaporin-2 Abundance and Degradation by Protein Kinase A and p38-MAP Kinase
NEDVETSKY, Pavel I, TABOR, Vedrana, WIESNER, Burkhard, BACHMANN, Sebastian, ROSENTHAL, Walter, KLUSSMANN, Enno, TAMMA, Grazia, BEULSHAUSEN, Sven, SKROBLIN, Philipp, KIRSCHNER, Aline, MUTIG, Kerim, BOLTZEN, Mareike, PETRUCCI, Oscar, VOSSENKÄMPER, Anna
Published in Journal of the American Society of Nephrology (01.10.2010)
Published in Journal of the American Society of Nephrology (01.10.2010)
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Journal Article
Demonstration of the functional impact of vasopressin signaling in the thick ascending limb by a targeted transgenic rat approach
Mutig, Kerim, Borowski, Tordis, Boldt, Christin, Borschewski, Aljona, Paliege, Alexander, Popova, Elena, Bader, Michael, Bachmann, Sebastian
Published in American journal of physiology. Renal physiology (01.08.2016)
Published in American journal of physiology. Renal physiology (01.08.2016)
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Journal Article
Loss of WNK3 is compensated for by the WNK1/SPAK axis in the kidney of the mouse
Mederle, Katharina, Mutig, Kerim, Paliege, Alexander, Carota, Isabel, Bachmann, Sebastian, Castrop, Hayo, Oppermann, Mona
Published in American journal of physiology. Renal physiology (01.05.2013)
Published in American journal of physiology. Renal physiology (01.05.2013)
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Journal Article
Can Molecular Biology Propose Reliable Biomarkers for Diagnosing Major Depression?
Ivanets, Nikolay N, Svistunov, Andrey A, Chubarev, Vladimir N, Kinkulkina, Marina A, Tikhonova, Yuliya G, Syzrantsev, Nikita S, Sologova, Susanna S, Ignatyeva, Nelly V, Mutig, Kerim, Tarasov, Vadim V
Published in Current pharmaceutical design (2021)
Published in Current pharmaceutical design (2021)
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Journal Article
Dynamic Modulation of Mouse Locus Coeruleus Neurons by Vasopressin 1a and 1b Receptors
Campos-Lira, Elba, Kelly, Louise, Seifi, Mohsen, Jackson, Torquil, Giesecke, Torsten, Mutig, Kerim, Koshimizu, Taka-Aki A, Hernandez, Vito S, Zhang, Limei, Swinny, Jerome D
Published in Frontiers in neuroscience (10.12.2018)
Published in Frontiers in neuroscience (10.12.2018)
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Journal Article