Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V
Moyer, Bryan D, Murray, Justin K, Ligutti, Joseph, Andrews, Kristin, Favreau, Philippe, Jordan, John B, Lee, Josie H, Liu, Dong, Long, Jason, Sham, Kelvin, Shi, Licheng, Stöcklin, Reto, Wu, Bin, Yin, Ruoyuan, Yu, Violeta, Zou, Anruo, Biswas, Kaustav, Miranda, Les P
Published in PloS one (01.05.2018)
Published in PloS one (01.05.2018)
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Purification of N-acetylgalactosamine-modified-oligonucleotides using orthogonal anion-exchange and mixed-mode chromatography approaches
Kazarian, Artaches A., Barnhart, Wesley, Long, Jason, Sham, Kelvin, Wu, Bin, Murray, Justin K.
Published in Journal of Chromatography A (04.01.2022)
Published in Journal of Chromatography A (04.01.2022)
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Journal Article
Engineering Potent and Selective Analogues of GpTx-1, a Tarantula Venom Peptide Antagonist of the NaV1.7 Sodium Channel
Murray, Justin K, Ligutti, Joseph, Liu, Dong, Zou, Anruo, Poppe, Leszek, Li, Hongyan, Andrews, Kristin L, Moyer, Bryan D, McDonough, Stefan I, Favreau, Philippe, Stöcklin, Reto, Miranda, Les P
Published in Journal of medicinal chemistry (12.03.2015)
Published in Journal of medicinal chemistry (12.03.2015)
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Journal Article
antiangiogenic neurokinin-B/thromboxane A2 regulatory axis
Pal, Saumen, Wu, Jing, Murray, Justin K, Gellman, Samuel H, Wozniak, Michele A, Keely, Patricia J, Boyer, Meghan E, Gomez, Timothy M, Hasso, Sean M, Fallon, John F, Bresnick, Emery H
Published in The Journal of cell biology (25.09.2006)
Published in The Journal of cell biology (25.09.2006)
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Journal Article
Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel
Murray, Justin K, Ligutti, Joseph, Liu, Dong, Zou, Anruo, Poppe, Leszek, Li, Hongyan, Andrews, Kristin L, Moyer, Bryan D, McDonough, Stefan I, Favreau, Philippe, Stöcklin, Reto, Miranda, Les P
Published in Journal of medicinal chemistry (12.03.2015)
Published in Journal of medicinal chemistry (12.03.2015)
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Journal Article
Single Residue Substitutions That Confer Voltage-Gated Sodium Ion Channel Subtype Selectivity in the NaV1.7 Inhibitory Peptide GpTx‑1
Murray, Justin K, Long, Jason, Zou, Anruo, Ligutti, Joseph, Andrews, Kristin L, Poppe, Leszek, Biswas, Kaustav, Moyer, Bryan D, McDonough, Stefan I, Miranda, Les P
Published in Journal of medicinal chemistry (24.03.2016)
Published in Journal of medicinal chemistry (24.03.2016)
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Journal Article
Purification of guanine-quadruplex using monolithic stationary phase under ion-exchange conditions
Kazarian, Artaches A., Barnhart, Wesley, Campuzano, Iain D.G., Cabrera, Jeremy, Fitch, Theodore, Long, Jason, Sham, Kelvin, Wu, Bin, Murray, Justin K.
Published in Journal of Chromatography A (20.12.2020)
Published in Journal of Chromatography A (20.12.2020)
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Journal Article
Discovery of Tarantula Venom-Derived NaV1.7-Inhibitory JzTx‑V Peptide 5‑Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis
Wu, Bin, Murray, Justin K, Andrews, Kristin L, Sham, Kelvin, Long, Jason, Aral, Jennifer, Ligutti, Joseph, Amagasu, Shanti, Liu, Dong, Zou, Anruo, Min, Xiaoshan, Wang, Zhulun, Ilch, Christopher P, Kornecook, Thomas J, Lin, Min-Hwa Jasmine, Be, Xuhai, Miranda, Les P, Moyer, Bryan D, Biswas, Kaustav
Published in Journal of medicinal chemistry (08.11.2018)
Published in Journal of medicinal chemistry (08.11.2018)
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Journal Article
Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3
Murray, Justin K., Qian, Yi-Xin, Liu, Benxian, Elliott, Robin, Aral, Jennifer, Park, Cynthia, Zhang, Xuxia, Stenkilsson, Michael, Salyers, Kevin, Rose, Mark, Li, Hongyan, Yu, Steven, Andrews, Kristin L., Colombero, Anne, Werner, Jonathan, Gaida, Kevin, Sickmier, E. Allen, Miu, Peter, Itano, Andrea, McGivern, Joseph, Gegg, Colin V., Sullivan, John K., Miranda, Les P.
Published in Journal of medicinal chemistry (10.09.2015)
Published in Journal of medicinal chemistry (10.09.2015)
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Journal Article
Sustained inhibition of the NaV1.7 sodium channel by engineered dimers of the domain II binding peptide GpTx-1
Murray, Justin K., Biswas, Kaustav, Holder, J. Ryan, Zou, Anruo, Ligutti, Joseph, Liu, Dong, Poppe, Leszek, Andrews, Kristin L., Lin, Fen-Fen, Meng, Shi-Yuan, Moyer, Bryan D., McDonough, Stefan I., Miranda, Les P.
Published in Bioorganic & medicinal chemistry letters (01.11.2015)
Published in Bioorganic & medicinal chemistry letters (01.11.2015)
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Journal Article
Identification and Optimization of a Minor Allele-Specific siRNA to Prevent PNPLA3 I148M-Driven Nonalcoholic Fatty Liver Disease
Murray, Justin K, Long, Jason, Liu, Lei, Singh, Shivani, Pruitt, Danielle, Ollmann, Michael, Swearingen, Elissa, Hardy, Miki, Homann, Oliver, Wu, Bin, Holder, Jerry Ryan, Sham, Kelvin, Herberich, Brad, Lo, Mei-Chu, Dou, Hui, Shkumatov, Artem, Florio, Monica, Rulifson, Ingrid C
Published in Nucleic acid therapeutics (01.10.2021)
Published in Nucleic acid therapeutics (01.10.2021)
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Journal Article
Engineering Antibody Reactivity for Efficient Derivatization to Generate NaV1.7 Inhibitory GpTx‑1 Peptide–Antibody Conjugates
Biswas, Kaustav, Nixey, Thomas E, Murray, Justin K, Falsey, James R, Yin, Li, Liu, Hantao, Gingras, Jacinthe, Hall, Brian E, Herberich, Brad, Holder, Jerry Ryan, Li, Hongyan, Ligutti, Joseph, Lin, Min-Hwa Jasmine, Liu, Dong, Soriano, Brian D, Soto, Marcus, Tran, Linh, Tegley, Christopher M, Zou, Anrou, Gunasekaran, Kannan, Moyer, Bryan D, Doherty, Liz, Miranda, Les P
Published in ACS chemical biology (15.09.2017)
Published in ACS chemical biology (15.09.2017)
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Journal Article
Discovery of Tarantula Venom-Derived Na V 1.7-Inhibitory JzTx-V Peptide 5-Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis
Wu, Bin, Murray, Justin K, Andrews, Kristin L, Sham, Kelvin, Long, Jason, Aral, Jennifer, Ligutti, Joseph, Amagasu, Shanti, Liu, Dong, Zou, Anruo, Min, Xiaoshan, Wang, Zhulun, Ilch, Christopher P, Kornecook, Thomas J, Lin, Min-Hwa Jasmine, Be, Xuhai, Miranda, Les P, Moyer, Bryan D, Biswas, Kaustav
Published in Journal of medicinal chemistry (08.11.2018)
Published in Journal of medicinal chemistry (08.11.2018)
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Journal Article
Liver-specific mitochondrial amidoxime-reducing component 1 (Mtarc1) knockdown protects the liver from diet-induced MASH in multiple mouse models
Guo, Yuanjun, Gao, Zhengyu, LaGory, Edward L, Kristin, Lewis Wilson, Gupte, Jamila, Gong, Yan, Rardin, Matthew J, Liu, Tongyu, Nguyen, Thong T, Long, Jason, Hsu, Yi-Hsiang, Murray, Justin K, Lade, Julie, Jackson, Simon, Zhang, Jun
Published in Hepatology communications (01.05.2024)
Published in Hepatology communications (01.05.2024)
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Journal Article
Exploration of Backbone Space in Foldamers Containing α- and β-Amino Acid Residues: Developing Protease-Resistant Oligomers that Bind Tightly to the BH3-Recognition Cleft of Bcl-xL
Sadowsky, Jack D., Murray, Justin K., Tomita, York, Gellman, Samuel H.
Published in Chembiochem : a European journal of chemical biology (25.05.2007)
Published in Chembiochem : a European journal of chemical biology (25.05.2007)
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Journal Article
Engineering Na V 1.7 Inhibitory JzTx-V Peptides with a Potency and Basicity Profile Suitable for Antibody Conjugation To Enhance Pharmacokinetics
Murray, Justin K, Wu, Bin, Tegley, Christopher M, Nixey, Thomas E, Falsey, James R, Herberich, Brad, Yin, Li, Sham, Kelvin, Long, Jason, Aral, Jennifer, Cheng, Yuan, Netirojjanakul, Chawita, Doherty, Liz, Glaus, Charles, Ikotun, Tayo, Li, Hongyan, Tran, Linh, Soto, Marcus, Salimi-Moosavi, Hossein, Ligutti, Joseph, Amagasu, Shanti, Andrews, Kristin L, Be, Xuhai, Lin, Min-Hwa Jasmine, Foti, Robert S, Ilch, Christopher P, Youngblood, Beth, Kornecook, Thomas J, Karow, Margaret, Walker, Kenneth W, Moyer, Bryan D, Biswas, Kaustav, Miranda, Les P
Published in ACS chemical biology (19.04.2019)
Published in ACS chemical biology (19.04.2019)
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