Activation of Alternative Bilirubin Clearance Pathways Partially Reduces Hyperbilirubinemia in a Mouse Model Lacking Functional Ugt1a1 Activity
Banerjee, Bhaswati, Olajide, Olayemi Joseph, Bortolussi, Giulia, Muro, Andrés F.
Published in International journal of molecular sciences (14.09.2022)
Published in International journal of molecular sciences (14.09.2022)
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Journal Article
Beclin‐1‐mediated activation of autophagy improves proximal and distal urea cycle disorders
Soria, Leandro R, Gurung, Sonam, De Sabbata, Giulia, Perocheau, Dany P, De Angelis, Angela, Bruno, Gemma, Polishchuk, Elena, Paris, Debora, Cuomo, Paola, Motta, Andrea, Orford, Michael, Khalil, Youssef, Eaton, Simon, Mills, Philippa B, Waddington, Simon N, Settembre, Carmine, Muro, Andrés F, Baruteau, Julien, Brunetti‐Pierri, Nicola
Published in EMBO molecular medicine (05.02.2021)
Published in EMBO molecular medicine (05.02.2021)
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Journal Article
Modulation of bilirubin neurotoxicity by the Abcb1 transporter in the Ugt1-/- lethal mouse model of neonatal hyperbilirubinemia
Bockor, Luka, Bortolussi, Giulia, Vodret, Simone, Iaconcig, Alessandra, Jašprová, Jana, Zelenka, Jaroslav, Vitek, Libor, Tiribelli, Claudio, Muro, Andrés F
Published in Human molecular genetics (01.01.2017)
Published in Human molecular genetics (01.01.2017)
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Journal Article
Coupling AAV-mediated promoterless gene targeting to SaCas9 nuclease to efficiently correct liver metabolic diseases
De Caneva, Alessia, Porro, Fabiola, Bortolussi, Giulia, Sola, Riccardo, Lisjak, Michela, Barzel, Adi, Giacca, Mauro, Kay, Mark A, Vlahoviček, Kristian, Zentilin, Lorena, Muro, Andrés F
Published in JCI insight (08.08.2019)
Published in JCI insight (08.08.2019)
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Journal Article
Preclinical Development of an AAV8-hUGT1A1 Vector for the Treatment of Crigler-Najjar Syndrome
Collaud, Fanny, Bortolussi, Giulia, Guianvarc'h, Laurence, Aronson, Sem J, Bordet, Thierry, Veron, Philippe, Charles, Severine, Vidal, Patrice, Sola, Marcelo Simon, Rundwasser, Stephanie, Dufour, Delphine G, Lacoste, Florence, Luc, Cyril, Wittenberghe, Laetitia V, Martin, Samia, Le Bec, Christine, Bosma, Piter J, Muro, Andres F, Ronzitti, Giuseppe, Hebben, Matthias, Mingozzi, Federico
Published in Molecular therapy. Methods & clinical development (15.03.2019)
Published in Molecular therapy. Methods & clinical development (15.03.2019)
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Journal Article
EMILIN1/α9β1 Integrin Interaction Is Crucial in Lymphatic Valve Formation and Maintenance
Danussi, Carla, Del Bel Belluz, Lisa, Pivetta, Eliana, Modica, Teresa Maria Elisa, Muro, Andres, Wassermann, Bruna, Doliana, Roberto, Sabatelli, Patrizia, Colombatti, Alfonso, Spessotto, Paola
Published in Molecular and Cellular Biology (01.11.2013)
Published in Molecular and Cellular Biology (01.11.2013)
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Journal Article
The extra domain A of fibronectin is essential for allergen-induced airway fibrosis and hyperresponsiveness in mice
Kohan, Martin, MSc, Muro, Andres F., PhD, Bader, Reem, MSc, Berkman, Neville, MBBCh, FRCP
Published in Journal of allergy and clinical immunology (01.02.2011)
Published in Journal of allergy and clinical immunology (01.02.2011)
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Journal Article
A translationally optimized AAV-UGT1A1 vector drives safe and long-lasting correction of Crigler-Najjar syndrome
Ronzitti, Giuseppe, Bortolussi, Giulia, van Dijk, Remco, Collaud, Fanny, Charles, Severine, Leborgne, Christian, Vidal, Patrice, Martin, Samia, Gjata, Bernard, Sola, Marcelo Simon, van Wittenberghe, Laetitia, Vignaud, Alban, Veron, Philippe, Bosma, Piter J, Muro, Andres F, Mingozzi, Federico
Published in Molecular therapy. Methods & clinical development (01.01.2016)
Published in Molecular therapy. Methods & clinical development (01.01.2016)
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Journal Article
Gene Therapy in Patients with the Crigler–Najjar Syndrome
D’Antiga, Lorenzo, Beuers, Ulrich, Ronzitti, Giuseppe, Brunetti-Pierri, Nicola, Baumann, Ulrich, Di Giorgio, Angelo, Aronson, Sem, Hubert, Aurelie, Romano, Roberta, Junge, Norman, Bosma, Piter, Bortolussi, Giulia, Muro, Andrés F., Soumoudronga, Ravaka F., Veron, Philippe, Collaud, Fanny, Knuchel-Legendre, Nathalie, Labrune, Philippe, Mingozzi, Federico
Published in The New England journal of medicine (17.08.2023)
Published in The New England journal of medicine (17.08.2023)
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Journal Article
Bilirubin-Induced Oxidative Stress Leads to DNA Damage in the Cerebellum of Hyperbilirubinemic Neonatal Mice and Activates DNA Double-Strand Break Repair Pathways in Human Cells
Tiribelli, Claudio, Gazzin, Silvia, Bortolussi, Giulia, Rawat, Vipin, Muro, Andrés F.
Published in Oxidative medicine and cellular longevity (01.01.2018)
Published in Oxidative medicine and cellular longevity (01.01.2018)
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Journal Article
Long-distance regulation of Add2 pre-mRNA3'end processing
Nedeljkovic, Mirjana, Costessi, Luisa, Iaconcig, Alessandra, Porro, Fabiola, Muro, Andrés F
Published in RNA biology (01.04.2013)
Published in RNA biology (01.04.2013)
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Journal Article
Attenuation of neuro-inflammation improves survival and neurodegeneration in a mouse model of severe neonatal hyperbilirubinemia
Vodret, Simone, Bortolussi, Giulia, Iaconcig, Alessandra, Martinelli, Elena, Tiribelli, Claudio, Muro, Andrés F.
Published in Brain, behavior, and immunity (01.05.2018)
Published in Brain, behavior, and immunity (01.05.2018)
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Journal Article
Fludarabine increases nuclease-free AAV- and CRISPR/Cas9-mediated homologous recombination in mice
Tsuji, Shinnosuke, Stephens, Calvin J., Bortolussi, Giulia, Zhang, Feijie, Baj, Gabriele, Jang, Hagoon, de Alencastro, Gustavo, Muro, Andrés F., Pekrun, Katja, Kay, Mark A.
Published in Nature biotechnology (01.08.2022)
Published in Nature biotechnology (01.08.2022)
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Journal Article
An Essential Role for Fibronectin Extra Type III Domain A in Pulmonary Fibrosis
Muro, Andres F, Moretti, Federico A, Moore, Bethany B, Yan, Mei, Atrasz, Rachelle G, Wilke, Carol A, Flaherty, Kevin R, Martinez, Fernando J, Tsui, Jessica L, Sheppard, Dean, Baralle, Francisco E, Toews, Galen B, White, Eric S
Published in American journal of respiratory and critical care medicine (15.03.2008)
Published in American journal of respiratory and critical care medicine (15.03.2008)
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Journal Article
Low efficacy of recombinant SV40 in Ugt1a1-/- mice with severe inherited hyperbilirubinemia
Shi, Xiaoxia, Bortolussi, Giulia, Bloemendaal, Lysbeth Ten, Duijst, Suzanne, Muro, Andrés F, Bosma, Piter J
Published in PloS one (01.01.2021)
Published in PloS one (01.01.2021)
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