Anti-B-Cell Maturation Antigen BiTE Molecule AMG 420 Induces Responses in Multiple Myeloma
Topp, Max S, Duell, Johannes, Zugmaier, Gerhard, Attal, Michel, Moreau, Philippe, Langer, Christian, Krönke, Jan, Facon, Thierry, Salnikov, Alexey V, Lesley, Robin, Beutner, Karl, Kalabus, James, Rasmussen, Erik, Riemann, Kathrin, Minella, Alex C, Munzert, Gerd, Einsele, Hermann
Published in Journal of clinical oncology (10.03.2020)
Published in Journal of clinical oncology (10.03.2020)
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Phase I Dose Escalation and Pharmacokinetic Study of BI 2536, a Novel Polo-Like Kinase 1 Inhibitor, in Patients With Advanced Solid Tumors
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Published in Journal of clinical oncology (01.12.2008)
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Phase I trial of volasertib, a Polo-like kinase inhibitor, plus platinum agents in solid tumors: safety, pharmacokinetics and activity
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Bortezomib, Dexamethasone, and Fibroblast Growth Factor Receptor 3–Specific Tyrosine Kinase Inhibitor in t(4;14) Myeloma
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An Open-label Dose-escalation Study of BIBF 1120 in Patients with Relapsed or Refractory Multiple Myeloma
KROPFF, Martin, KIENAST, Joachim, LISPING, Guido, BERDEL, Wolfgang E, GASCHLER-MARKEFSKI, Birgit, STOPFER, Peter, STEFANIC, Martin, MUNZERT, Gerd
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Growth inhibition and induction of apoptosis in acute myeloid leukemia cells by new indolinone derivatives targeting fibroblast growth factor, platelet-derived growth factor, and vascular endothelial growth factor receptors
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Published in Molecular cancer therapeutics (01.12.2006)
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Phase I Dose-Escalation Trial of BI 2536, a Polo-Like Kinase 1 Inhibitor, in Relapsed and Refractory Non-Hodgkin's Lymphoma
Vose, Julie M., Young, Anas, Friedberg, Jonathan W., Waller, Edmund K., Cheson, Bruce D., Trommeshauser, Dirk, Munzert, Gerd
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A phase I, dose-escalation study of the novel Polo-like kinase inhibitor volasertib (BI 6727) in patients with advanced solid tumours
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Molecular cloning of the human histamine H2 receptor
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The SH2-containing adapter protein GRB10 interacts with BCR-ABL
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The Efficacy and Safety of BI 2536, a Novel Plk-1 Inhibitor, in Patients with Stage IIIB/IV Non-small Cell Lung Cancer Who Had Relapsed after, or Failed, Chemotherapy: Results from an Open-Label, Randomized Phase II Clinical Trial
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Published in Journal of thoracic oncology (01.07.2010)
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Treatment with AMG 420, an Anti-B-Cell Maturation Antigen (BCMA) Bispecific T-Cell Engager (BiTE®) Antibody Construct, Induces Minimal Residual Disease (MRD) Negative Complete Responses in Relapsed and/or Refractory (R/R) Multiple Myeloma (MM) Patients: Results of a First-in-Human (FIH) Phase I Dose Escalation Study
Topp, Max S., Duell, Johannes, Zugmaier, Gerhard, Attal, Michel, Moreau, Philippe, Langer, Christian, Kroenke, Jan, Facon, Thierry, Einsele, Hermann, Munzert, Gerd
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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An Open-Label, Phase II Study of the Polo-like Kinase-1 (Plk-1) Inhibitor, BI 2536, in Patients with Relapsed Small Cell Lung Cancer (SCLC)
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Published in Lung cancer (Amsterdam, Netherlands) (01.02.2017)
Published in Lung cancer (Amsterdam, Netherlands) (01.02.2017)
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An Open-Label, Phase I Study of the Polo-like Kinase-1 Inhibitor, BI 2536, in Patients with Advanced Solid Tumors
HOFHEINZ, Ralf-Dieter, AL-BATRAN, Salah-Eddin, HOCHHAUS, Andreas, JÄGER, Elke, REICHARDT, Volker L, FRITSCH, Holger, TROMMESHAUSER, Dirk, MUNZERT, Gerd
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Published in Clinical cancer research (15.09.2010)
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Evaluation of AMG 420, an anti-BCMA bispecific T-cell engager (BiTE) immunotherapy, in R/R multiple myeloma (MM) patients: Updated results of a first-in-human (FIH) phase I dose escalation study
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Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
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Multicentric parallel phase II trial of the polo-like kinase 1 inhibitor BI 2536 in patients with advanced head and neck cancer, breast cancer, ovarian cancer, soft tissue sarcoma and melanoma. The first protocol of the European Organization for Research and Treatment of Cancer (EORTC) Network Of Core Institutes (NOCI)
Schöffski, Patrick, Blay, Jean-Yves, De Greve, Jacques, Brain, Etienne, Machiels, Jean-Pascal, Soria, Jean-Charles, Sleijfer, Stefan, Wolter, Pascal, Ray-Coquard, Isabelle, Fontaine, Christel, Munzert, Gerd, Fritsch, Holger, Hanft, Gertraud, Aerts, Claire, Rapion, Jérome, Allgeier, Anouk, Bogaerts, Jan, Lacombe, Denis
Published in European journal of cancer (1990) (01.08.2010)
Published in European journal of cancer (1990) (01.08.2010)
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Phase 1 dose-escalation study of BI 836909, an anti-BCMA bi-specific T-cell engager, in relapsed and/or refractory multiple myeloma (RRMM)
Topp, Max S., Attal, Michel, Langer, Christian, Moreau, Philippe, Facon, Thierry, Düll, Johannes, Hebraud, Benjamin, Gomez-Roca, Carlos, Munzert, Gerd Michael, Gracien, Edith, Zugmaier, Gerhard, Einsele, Hermann
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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A randomized, open‐label, phase I/II trial to investigate the maximum tolerated dose of the Polo‐like kinase inhibitor BI 2536 in elderly patients with refractory/relapsed acute myeloid leukaemia
Müller‐Tidow, Carsten, Bug, Gesine, Lübbert, Michael, Krämer, Alwin, Krauter, Jürgen, Valent, Peter, Nachbaur, David, Berdel, Wolfgang E., Ottmann, Oliver G., Fritsch, Holger, Munzert, Gerd, Garin‐Chesa, Pilar, Fleischer, Frank, Taube, Tillmann, Döhner, Hartmut
Published in British journal of haematology (01.10.2013)
Published in British journal of haematology (01.10.2013)
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