Model‐informed assessment of ethnic sensitivity and dosage justification for Asian populations in the global clinical development and use of cladribine tablets
Munafo, Alain, Terranova, Nadia, Li, Dandan, Liu, Ping, Venkatakrishnan, Karthik
Published in Clinical and translational science (01.02.2022)
Published in Clinical and translational science (01.02.2022)
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Journal Article
Predicting disease activity in patients with multiple sclerosis: An explainable machine‐learning approach in the Mavenclad trials
Basu, Sreetama, Munafo, Alain, Ben‐Amor, Ali‐Frederic, Roy, Sanjeev, Girard, Pascal, Terranova, Nadia
Published in CPT: pharmacometrics and systems pharmacology (01.07.2022)
Published in CPT: pharmacometrics and systems pharmacology (01.07.2022)
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Journal Article
Designing phase I oncology dose escalation using dose–exposure–toxicity models as a complementary approach to model‐based dose–toxicity models
Pantoja, Kristyn, Lanke, Shankar, Munafo, Alain, Victor, Anja, Habermehl, Christina, Schueler, Armin, Venkatakrishnan, Karthik, Girard, Pascal, Goteti, Kosalaram
Published in CPT: pharmacometrics and systems pharmacology (01.10.2022)
Published in CPT: pharmacometrics and systems pharmacology (01.10.2022)
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Journal Article
Cladribine as a Potential Object of Nucleoside Transporter-Based Drug Interactions
Hermann, Robert, Krajcsi, Peter, Fluck, Markus, Seithel-Keuth, Annick, Bytyqi, Afrim, Galazka, Andrew, Munafo, Alain
Published in Clinical pharmacokinetics (01.02.2022)
Published in Clinical pharmacokinetics (01.02.2022)
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Journal Article
Effects of Postponing Treatment in the Second Year of Cladribine Administration: Clinical Trial Simulation Analysis of Absolute Lymphocyte Counts and Relapse Rate in Patients with Relapsing-Remitting Multiple Sclerosis
Terranova, Nadia, Hicking, Christine, Dangond, Fernando, Munafo, Alain
Published in Clinical pharmacokinetics (01.03.2019)
Published in Clinical pharmacokinetics (01.03.2019)
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Journal Article
Drug concentration response relationships in normal volunteers after oral administration of losartan, an angiotensin II receptor antagonist
Munafo, A, Christen, Y, Nussberger, J, Shum, L Y, Borland, R M, Lee, R J, Waeber, B, Biollaz, J, Brunner, H R
Published in Clinical pharmacology and therapeutics (01.05.1992)
Published in Clinical pharmacology and therapeutics (01.05.1992)
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Journal Article
Comment on: “Why Were More Than 200 Subjects Required to Demonstrate the Bioequivalence of a New Formulation of Levothyroxine with an Old One?”
Krebs-Brown, Axel, Munafo, Alain, Gaikwad, Sumedh, Urgatz, Bogumila, Castello-Bridoux, Claire
Published in Clinical pharmacokinetics (01.02.2020)
Published in Clinical pharmacokinetics (01.02.2020)
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Journal Article
Machine Learning Analysis of Individual Tumor Lesions in Four Metastatic Colorectal Cancer Clinical Studies: Linking Tumor Heterogeneity to Overall Survival
Vera-Yunca, Diego, Girard, Pascal, Parra-Guillen, Zinnia P., Munafo, Alain, Trocóniz, Iñaki F., Terranova, Nadia
Published in The AAPS journal (16.03.2020)
Published in The AAPS journal (16.03.2020)
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Journal Article
Effects of cladribine tablets on heart rate, atrio‐ventricular conduction and cardiac repolarization in patients with relapsing multiple sclerosis
Hermann, Robert, Litwin, Jeffrey S., Friberg, Lena E., Dangond, Fernando, Munafo, Alain
Published in British journal of clinical pharmacology (01.07.2019)
Published in British journal of clinical pharmacology (01.07.2019)
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Journal Article
Population Pharmacokinetics of Cladribine in Patients with Multiple Sclerosis
Savic, Radojka M., Novakovic, Ana M., Ekblom, Marianne, Munafo, Alain, Karlsson, Mats O.
Published in Clinical pharmacokinetics (01.10.2017)
Published in Clinical pharmacokinetics (01.10.2017)
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Journal Article
Comment on "Levothyrox® New and Old Formulations: Are They Switchable for Millions of Patients?"/Reply
Munafo, Alain, Krebs-Brown, Axel, Gaikwad, Sumedh, Urgatz, Bogumila, Castello-Bridoux, Claire, Concordet, Didier, Gandia, Peggy, Montastruc, Jean-Louis, Bousquet-Mélou, Alain, Lees, Peter, Ferran, Aude A, Toutain, Pierre-Louis
Published in Clinical pharmacokinetics (01.07.2019)
Published in Clinical pharmacokinetics (01.07.2019)
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Journal Article