A practical synthesis of (S) 3-tert-butoxycarbonylamino-2-oxo-2,3,4,5-tetrahydro-1,5-benzodiazepine-1-acetic acid methyl ester as a conformationally restricted dipeptido-mimetic for caspase-1 (ICE) inhibitors
LAUFFER, David J, MULLICAN, Michael D
Published in Bioorganic & medicinal chemistry letters (22.04.2002)
Published in Bioorganic & medicinal chemistry letters (22.04.2002)
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Journal Article
Design of 5-(3,5-di-tert-butyl-4-hydroxyphenyl)-1,3,4-thiadiazoles, -1,3,4-oxadiazoles, and -1,2,4-triazoles as orally active, nonulcerogenic antiinflammatory agents
Mullican, Michael D, Wilson, Michael W, Conner, David T, Kostlan, Catherine R, Schrier, Denis J, Dyer, Richard D
Published in Journal of medicinal chemistry (01.04.1993)
Published in Journal of medicinal chemistry (01.04.1993)
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Novel benzothiophene-, benzofuran-, and naphthalenecarboxamidotetrazoles as potential antiallergy agents
Connor, David T, Cetenko, Wiaczeslaw A, Mullican, Michael D, Sorenson, Roderick J, Unangst, Paul C, Weikert, Robert J, Adolphson, Richard L, Kennedy, John A, Thueson, David O
Published in Journal of medicinal chemistry (01.03.1992)
Published in Journal of medicinal chemistry (01.03.1992)
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Inverse electron demand Diels-Alder reactions of 3-carbomethoxy-2-pyrones. Controlled introduction of oxygenated aromatics: benzene, phenol, catechol, resorcinol, and pyrogallol annulation. Regiospecific total synthesis of sendaverine and a preparation of 6,7-benzomorphans
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Journal Article
NOVEL BENZOTHIOPHENS HAVING ANTIALLERGIC ACTIVITY
THUESON, DAVID O, CONNOR, DAVID T, MULLICAN, MICHAEL D, SORENSON, RODERICK J
Year of Publication 12.07.1997
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Year of Publication 12.07.1997
Patent
Thermal cycloaddition of 1,3,5-triazine with enamines: regiospecific pyrimidine annulation
Boger, Dale L, Schumacher, Jane, Mullican, Michael D, Patel, Mona, Panek, James S
Published in Journal of organic chemistry (01.06.1982)
Published in Journal of organic chemistry (01.06.1982)
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Journal Article
Novel thiophene-, pyrrole-, furan-, and benzene carboxamidotetrazoles as potential antiallergy agents
Mullican, Michael D, Sorenson, Roderick J, Connor, David T, Thueson, David O, Kennedy, John A, Conroy, Mary Carol
Published in Journal of medicinal chemistry (01.07.1991)
Published in Journal of medicinal chemistry (01.07.1991)
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Chemogenomic approaches to drug discovery
Caron, Paul R, Mullican, Michael D, Mashal, Robert D, Wilson, Keith P, Su, Michael S, Murcko, Mark A
Published in Current opinion in chemical biology (01.08.2001)
Published in Current opinion in chemical biology (01.08.2001)
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Structure-based design of non-peptidic pyridone aldehydes as inhibitors of interleukin-1β converting enzyme
Golec, Julian M.C., Mullican, Michael D., Murcko, Mark A., Wilson, Keith P., Kay, David P., Jones, Stuart D., Murdoch, Robert, Bemis, Guy W., Raybuck, Scott A., Luong, Yu-Ping, Livingston, David J.
Published in Bioorganic & medicinal chemistry letters (09.09.1997)
Published in Bioorganic & medicinal chemistry letters (09.09.1997)
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The synthesis and evaluation of peptidyl aspartyl aldehydes as inhibitors of ice
Mullican, Michael D., Lauffer, David J., Gillespie, Roger J., Matharu, Saroop S., Kay, David, Porritt, Geoffrey M., Evans, Phillip L., Golec, Julian M.C., Murcko, Mark A., Luong, Yu-Ping, Raybuck, Scott A., Livingston, David J.
Published in Bioorganic & medicinal chemistry letters (06.10.1994)
Published in Bioorganic & medicinal chemistry letters (06.10.1994)
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compostos inibidores de caspases, composição farmacêutica e uso de ditos compostos
David J. Lauffer, Keith P. Wilson, Marion W. Wannamaker, Mark A. Murcko, James W. Janetka, Michael D. Mullican, Paul S. Charifson, Cornelia J. Forster, Robert J. Davies, Anne-Laure Grillot, Guy W. Bemis, Zhan Shi
Year of Publication 25.05.2021
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Year of Publication 25.05.2021
Patent
INHIBITORS OF INTERLEUKIN-1 BETA CONVERTING ENZYME
BEMIS GUY W, LAUFFER DAVID J, LIVINGSTON DAVID J, GOLEC JULIAN M. C, MULLICAN MICHAEL D, MURCKO MARK A
Year of Publication 20.09.2012
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Year of Publication 20.09.2012
Patent
Inhibitors of caspases
BEMIS GUY W, GRILLOT ANNE-LAURE, WANNAMAKER MARION W, LAUFFER DAVID J, SHI ZHAN, WILSON KEITH P, CHARIFSON PAUL S, MULLICAN MICHAEL D, JANETKA JAMES W, DAVIES ROBERT J, MURCKO MARK A, FORSTER CORNELIA J
Year of Publication 08.04.2014
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Year of Publication 08.04.2014
Patent
Inhibitors of interleukin-1 beta converting enzyme
BEMIS GUY W, LAUFFER DAVID J, LIVINGSTON DAVID J, GOLEC JULIAN M. C, MULLICAN MICHAEL D, MURCKO MARK A
Year of Publication 20.01.2011
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Year of Publication 20.01.2011
Patent