Lenalidomide Enhances Natural Killer Cell and Monocyte-Mediated Antibody-Dependent Cellular Cytotoxicity of Rituximab-Treated CD20+ Tumor Cells
Wu, Lei, Adams, Mary, Carter, Troy, Chen, Roger, Muller, George, Stirling, David, Schafer, Peter, Bartlett, J Blake
Published in Clinical cancer research (15.07.2008)
Published in Clinical cancer research (15.07.2008)
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Lenalidomide and CC-4047 inhibit the proliferation of malignant B cells while expanding normal CD34+ progenitor cells
VERHELLE, Dominique, CORRAL, Laura G, LOPEZ-GIRONA, Antonia, MUTTER, George W, BRADY, Helen A, CHAN, Kyle W. H, WONG, Kevin, MUELLER, Jessica H, MOUTOUH-DE PARSEVAL, Laure, JENSEN-PERGAKES, Kristen, SCHAFER, Peter H, CHEN, Roger, GLEZER, Emilia, FERGUSON, Gregory D
Published in Cancer research (Chicago, Ill.) (15.01.2007)
Published in Cancer research (Chicago, Ill.) (15.01.2007)
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Discovery of (S)-N-{2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide (Apremilast), a Potent and Orally Active Phosphodiesterase 4 and Tumor Necrosis Factor-α Inhibitor
Man, Hon-Wah, Schafer, Peter, Wong, Lu Min, Patterson, Rebecca T, Corral, Laura G, Raymon, Heather, Blease, Kate, Leisten, Jim, Shirley, Michael A, Tang, Yang, Babusis, Darius M, Chen, Roger, Stirling, Dave, Muller, George W
Published in Journal of medicinal chemistry (26.03.2009)
Published in Journal of medicinal chemistry (26.03.2009)
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The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions
Lu, Ling, Payvandi, Faribourz, Wu, Lei, Zhang, Ling-Hua, Hariri, Robert J, Man, Hon-Wah, Chen, Roger S., Muller, George W., Hughes, Christopher C.W., Stirling, David I., Schafer, Peter H., Bartlett, J. Blake
Published in Microvascular research (01.03.2009)
Published in Microvascular research (01.03.2009)
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Discovery of (S)-N-{2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide (Apremilast), a Potent and Orally Active Phosphodiesterase 4 and Tumor Necrosis Factor-a Inhibitor
MAN, Hon-Wah, SCHAFER, Peter, BABUSIS, Darius M, CHEN, Roger, STIRLING, Dave, MULLER, George W, LU MIN WONG, PATTERSON, Rebecca T, CORRAL, Laura G, RAYMON, Heather, BLEASE, Kate, LEISTEN, Jim, SHIRLEY, Michael A, YANG TANG
Published in Journal of medicinal chemistry (26.03.2009)
Published in Journal of medicinal chemistry (26.03.2009)
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Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungs
Subbian, Selvakumar, Tsenova, Liana, O'Brien, Paul, Yang, Guibin, Koo, Mi-Sun, Peixoto, Blas, Fallows, Dorothy, Dartois, Veronique, Muller, George, Kaplan, Gilla
Published in PLoS pathogens (01.09.2011)
Published in PLoS pathogens (01.09.2011)
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Isosteric analogs of lenalidomide and pomalidomide: Synthesis and biological activity
Ruchelman, Alexander L., Man, Hon-Wah, Zhang, Weihong, Chen, Roger, Capone, Lori, Kang, Jian, Parton, Anastasia, Corral, Laura, Schafer, Peter H., Babusis, Darius, Moghaddam, Mehran F., Tang, Yang, Shirley, Michael A., Muller, George W.
Published in Bioorganic & medicinal chemistry letters (01.01.2013)
Published in Bioorganic & medicinal chemistry letters (01.01.2013)
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Thalidomide and Lenalidomide Extend Survival in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis
Kiaei, Mahmoud, Petri, Susanne, Kipiani, Khatuna, Gardian, Gabrielle, Choi, Dong-Kug, Chen, Junyu, Calingasan, Noel Y, Schafer, Peter, Muller, George W, Stewart, Charles, Hensley, Kenneth, Beal, M. Flint
Published in The Journal of neuroscience (01.03.2006)
Published in The Journal of neuroscience (01.03.2006)
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Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma
Davies, Faith E., Raje, Noopur, Hideshima, Teru, Lentzsch, Suzanne, Young, Gloria, Tai, Yu-Tzu, Lin, Boris, Podar, Klaus, Gupta, Deepak, Chauhan, Dharminder, Treon, Steven P., Richardson, Paul G., Schlossman, Robert L., Morgan, Gareth J., Muller, George W., Stirling, David I., Anderson, Kenneth C.
Published in Blood (01.07.2001)
Published in Blood (01.07.2001)
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Phosphodiesterase 4 inhibition reduces innate immunity and improves isoniazid clearance of Mycobacterium tuberculosis in the lungs of infected mice
Koo, Mi-Sun, Manca, Claudia, Yang, Guibin, O'Brien, Paul, Sung, Nackmoon, Tsenova, Liana, Subbian, Selvakumar, Fallows, Dorothy, Muller, George, Ehrt, Sabine, Kaplan, Gilla
Published in PloS one (25.02.2011)
Published in PloS one (25.02.2011)
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Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy
Hideshima, Teru, Chauhan, Dharminder, Shima, Yoshihito, Raje, Noopur, Davies, Faith E., Tai, Yu-Tzu, Treon, Steven P., Lin, Boris, Schlossman, Robert L., Richardson, Paul, Muller, George, Stirling, David I., Anderson, Kenneth C.
Published in Blood (01.11.2000)
Published in Blood (01.11.2000)
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Combining Agents that Target the Tumor Microenvironment Improves the Efficacy of Anticancer Therapy
BLANSFIELD, Joseph A, CARAGACIANU, Diana, LIBUTTI, Steven K, ALEXANDER, H. Richard, TANGREA, Michael A, MORITA, Shane Y, LORANG, Dominique, SCHAFER, Peter, MULLER, George, STIRLING, David, ROYAL, Richard E
Published in Clinical cancer research (01.01.2008)
Published in Clinical cancer research (01.01.2008)
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1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4
Ruchelman, Alexander L., Man, Hon-Wah, Chen, Roger, Liu, Wei, Lu, Ling, Cedzik, Dorota, Zhang, Ling, Leisten, Jim, Collette, Alice, Narla, Rama Krishna, Raymon, Heather K., Muller, George W.
Published in Bioorganic & medicinal chemistry (01.11.2011)
Published in Bioorganic & medicinal chemistry (01.11.2011)
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Enhancement of Cytokine Production and AP-1 Transcriptional Activity in T Cells by Thalidomide-Related Immunomodulatory Drugs
Schafer, Peter H, Gandhi, Anita K, Loveland, Michelle A, Chen, Roger S, Man, Hon-Wah, Schnetkamp, Paul P M, Wolbring, Gregor, Govinda, Sowmya, Corral, Laura G, Payvandi, Faribourz, Muller, George W, Stirling, David I
Published in The Journal of pharmacology and experimental therapeutics (01.06.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2003)
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A pandemic influenza modeling and visualization tool
Maciejewski, Ross, Livengood, Philip, Rudolph, Stephen, Collins, Timothy F., Ebert, David S., Brigantic, Robert T., Corley, Courtney D., Muller, George A., Sanders, Stephen W.
Published in Journal of visual languages and computing (01.08.2011)
Published in Journal of visual languages and computing (01.08.2011)
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Combination therapy targeting the tumor microenvironment is effective in a model of human ocular melanoma
Mangiameli, David P, Blansfield, Joseph A, Kachala, Stephan, Lorang, Dominique, Schafer, Peter H, Muller, George W, Stirling, David I, Libutti, Steven K
Published in Journal of translational medicine (18.07.2007)
Published in Journal of translational medicine (18.07.2007)
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Protective Antitumor Immunity Induced by a Costimulatory Thalidomide Analog in Conjunction with Whole Tumor Cell Vaccination Is Mediated by Increased Th1-Type Immunity
Dredge, Keith, Marriott, J. Blake, Todryk, Stephen M, Muller, George W, Chen, Roger, Stirling, David I, Dalgleish, Angus G
Published in The Journal of immunology (1950) (15.05.2002)
Published in The Journal of immunology (1950) (15.05.2002)
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CC-5079: A Small Molecule with MKP1, Antiangiogenic, and Antitumor Activity
Vu, Huan N., M.D, Miller, Walter J., D.O, O'Connor, Sarah A., B.S, He, Mei, M.S, Schafer, Peter H., Ph.D, Payvandi, Faribourz, Ph.D, Muller, George W., Ph.D, Stirling, David I, Libutti, Steven K., M.D
Published in The Journal of surgical research (01.11.2010)
Published in The Journal of surgical research (01.11.2010)
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