Protein Degradation via CRL4(CRBN) Ubiquitin Ligase: Discovery and Structure-Activity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1
Hansen, Joshua D., Condroski, Kevin, Correa, Matthew, Muller, George, Man, Hon-Wah, Ruchelman, Alexander, Zhang, Weihong, Vocanson, Fan, Crea, Tim, Liu, Wei, Lu, Gang, Baculi, Frans, LeBrun, Laurie, Mahmoudi, Afshin, Carmel, Gilles, Hickman, Matt, Lu, Chin-Chun
Published in Journal of medicinal chemistry (25.01.2018)
Published in Journal of medicinal chemistry (25.01.2018)
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anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells
Galustian, Christine, Meyer, Brendan, Labarthe, Marie-Christine, Dredge, Keith, Klaschka, Deborah, Henry, Jake, Todryk, Stephen, Chen, Roger, Muller, George, Stirling, David, Schafer, Peter, Bartlett, J. Blake, Dalgleish, Angus G
Published in Cancer Immunology, Immunotherapy (01.07.2009)
Published in Cancer Immunology, Immunotherapy (01.07.2009)
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Effect of 3-fluorothalidomide and 3-methylthalidomide enantiomers on tumor necrosis factor production and antitumor responses to the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)
Chung, Francisco, Palmer, Brian D, Muller, George W, Man, Hon-Wah, Kestell, Phillip, Baguley, Bruce C, Ching, Lai-Ming
Published in Oncology research (2003)
Published in Oncology research (2003)
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Phosphodiesterase-4 Inhibition Combined with Isoniazid Treatment of Rabbits with Pulmonary Tuberculosis Reduces Macrophage Activation and Lung Pathology
Subbian, Selvakumar, Tsenova, Liana, O'Brien, Paul, Yang, Guibin, Koo, Mi-Sun, Peixoto, Blas, Fallows, Dorothy, Zeldis, Jerome B, Muller, George, Kaplan, Gilla
Published in The American journal of pathology (01.07.2011)
Published in The American journal of pathology (01.07.2011)
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Potent inhibition of cytokine production from intestinal lamina propria T cells by phosphodiesterase-4 inhibitory thalidomide analogues
PREHN, John L, LANDERS, Carol, MULLER, George W, MAN, Hon-Wah, STIRLING, David I, TARGAN, Stephan R
Published in Journal of clinical immunology (01.09.2001)
Published in Journal of clinical immunology (01.09.2001)
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Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells
Moutouh-de Parseval, Laure A, Verhelle, Dominique, Glezer, Emilia, Jensen-Pergakes, Kristen, Ferguson, Gregory D, Corral, Laura G, Morris, Christopher L, Muller, George, Brady, Helen, Chan, Kyle
Published in The Journal of clinical investigation (01.01.2008)
Published in The Journal of clinical investigation (01.01.2008)
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Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy
Hideshima, Teru, Chauhan, Dharminder, Shima, Yoshihito, Raje, Noopur, Davies, Faith E., Tai, Yu-Tzu, Treon, Steven P., Lin, Boris, Schlossman, Robert L., Richardson, Paul, Muller, George, Stirling, David I., Anderson, Kenneth C.
Published in Blood (01.11.2000)
Published in Blood (01.11.2000)
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Protein Degradation via CRL4 CRBN Ubiquitin Ligase: Discovery and Structure-Activity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1
Hansen, Joshua D, Condroski, Kevin, Correa, Matthew, Muller, George, Man, Hon-Wah, Ruchelman, Alexander, Zhang, Weihong, Vocanson, Fan, Crea, Tim, Liu, Wei, Lu, Gang, Baculi, Frans, LeBrun, Laurie, Mahmoudi, Afshin, Carmel, Gilles, Hickman, Matt, Lu, Chin-Chun
Published in Journal of medicinal chemistry (25.01.2018)
Published in Journal of medicinal chemistry (25.01.2018)
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Journal Article
Protein Degradation via CRL4CRBN Ubiquitin Ligase: Discovery and Structure–Activity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1
Hansen, Joshua D, Condroski, Kevin, Correa, Matthew, Muller, George, Man, Hon-Wah, Ruchelman, Alexander, Zhang, Weihong, Vocanson, Fan, Crea, Tim, Liu, Wei, Lu, Gang, Baculi, Frans, LeBrun, Laurie, Mahmoudi, Afshin, Carmel, Gilles, Hickman, Matt, Lu, Chin-Chun
Published in Journal of medicinal chemistry (25.01.2018)
Published in Journal of medicinal chemistry (25.01.2018)
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