Secondary pharmacology: screening and interpretation of off-target activities – focus on translation
Whitebread, Steven, Dumotier, Berengere, Armstrong, Duncan, Fekete, Alexander, Chen, Shanni, Hartmann, Andreas, Muller, Patrick Y., Urban, Laszlo
Published in Drug discovery today (01.08.2016)
Published in Drug discovery today (01.08.2016)
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Journal Article
Processing of gene expression data generated by quantitative real-time RT-PCR
MULLER, Patrick Y, JANOVJAK, Harald, MISEREZ, André R, DOBBIE, Zuzana
Published in BioTechniques (01.06.2002)
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Published in BioTechniques (01.06.2002)
Journal Article
The minimum anticipated biological effect level (MABEL) for selection of first human dose in clinical trials with monoclonal antibodies
Muller, Patrick Y, Milton, Mark, Lloyd, Peter, Sims, Jennifer, Brennan, Frank R
Published in Current opinion in biotechnology (01.12.2009)
Published in Current opinion in biotechnology (01.12.2009)
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Journal Article
A single-nucleotide polymorphism in the sterol-regulatory element-binding protein 1c gene is predictive of HIV-related hyperlipoproteinaemia
MISEREZ, André R, MULLER, Patrick Y, BARELLA, Luca, SCHWIETERT, Martin, ERB, Peter, VERNAZZA, Pietro L, BATTEGAY, Manuel
Published in AIDS (London) (19.10.2001)
Published in AIDS (London) (19.10.2001)
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Journal Article
Safety and immunotoxicity assessment of immunomodulatory monoclonal antibodies
Brennan, Frank R., Morton, Laura Dill, Spindeldreher, Sebastian, Kiessling, Andrea, Allenspach, Roy, Hey, Adam, Müller, Patrick, Frings, Werner, Sims, Jennifer
Published in mAbs (01.05.2010)
Published in mAbs (01.05.2010)
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Journal Article
Safety differentiation: emerging competitive edge in drug development
Uteng, Marianne, Urban, Laszlo, Brees, Dominique, Muller, Patrick Y., Kullak-Ublick, Gerd A., Bouchard, Page, Tougas, Gervais, Chibout, Salah-Dine
Published in Drug discovery today (01.01.2019)
Published in Drug discovery today (01.01.2019)
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Journal Article
Identification of hepatic molecular mechanisms of action of alpha-tocopherol using global gene expression profile analysis in rats
Barella, Luca, Muller, Patrick Y, Schlachter, Manfred, Hunziker, Willi, Stöcklin, Elisabeth, Spitzer, Volker, Meier, Nina, de Pascual-Teresa, Sonia, Minihane, Anne-Marie, Rimbach, Gerald
Published in Biochimica et biophysica acta (24.05.2004)
Published in Biochimica et biophysica acta (24.05.2004)
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Journal Article
Comparative quantification of pharmacodynamic parameters of chiral compounds ( RRR- vs. all-rac- α tocopherol) by global gene expression profiling
Muller, Patrick Y., Netscher, Thomas, Frank, Jan, Stoecklin, Elisabeth, Rimbach, Gerald, Barella, Luca
Published in Journal of plant physiology (01.07.2005)
Published in Journal of plant physiology (01.07.2005)
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Journal Article
Conference Proceeding
Sterol-regulatory element-binding protein (SREBP)-2 contributes to polygenic hypercholesterolaemia
Miserez, André R., Muller, Patrick Y., Barella, Luca, Barella, Sandra, Staehelin, Hannes B., Leitersdorf, Eran, Kark, Jeremy D., Friedlander, Yechiel
Published in Atherosclerosis (01.09.2002)
Published in Atherosclerosis (01.09.2002)
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Journal Article
Expression of COX-2 and Wnt pathway genes in adenomas of familial adenomatous polyposis patients treated with meloxicam
Dobbie, Zuzana, Muller, Patrick Y, Heinimann, Karl, Albrecht, Christiane, D'Orazio, Daniel, Bendik, Igor, Müller, Hansjakob, Bauerfeind, Peter
Published in Anticancer research (01.07.2002)
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Published in Anticancer research (01.07.2002)
Journal Article
Overexpression of Wnt target genes in adenomas of familial adenomatous polyposis patients
D'Orazio, Daniel, Muller, Patrick Y, Heinimann, Karl, Albrecht, Christiane, Bendik, Igor, Herzog, Urs, Tondelli, Peter, Bauerfeind, Peter, Müller, Hansjakob, Dobbie, Zuzana
Published in Anticancer research (01.11.2002)
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Published in Anticancer research (01.11.2002)
Journal Article