TBX2 acts as a potent transcriptional silencer of tumour suppressor genes through interaction with the CoREST complex to sustain the proliferation of breast cancers
McIntyre, Alexander J, Angel, Charlotte Z, Smith, James S, Templeman, Amy, Beattie, Katherine, Beattie, Shannon, Ormrod, Alice, Devlin, Eadaoin, McGreevy, Charles, Bothwell, Chloe, Eddie, Sharon L, Buckley, Niamh E, Williams, Rich, Mullan, Paul B
Published in Nucleic acids research (24.06.2022)
Published in Nucleic acids research (24.06.2022)
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BRD7, a Subunit of SWI/SNF Complexes, Binds Directly to BRCA1 and Regulates BRCA1-Dependent Transcription
HARTE, Mary T, O'BRIEN, Garrett J, RYAN, Niamh M, GORSKI, Julia J, SAVAGE, Kienan I, CRAWFORD, Nyree T, MULLAN, Paul B, HARKIN, D. Paul
Published in Cancer research (Chicago, Ill.) (15.03.2010)
Published in Cancer research (Chicago, Ill.) (15.03.2010)
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BRCA1 mRNA Expression Levels Predict for Overall Survival in Ovarian Cancer after Chemotherapy
Quinn, Jennifer E, James, Colin R, Stewart, Gail E, Mulligan, Jude M, White, Patricia, Chang, Gary K F, Mullan, Paul B, Johnston, Patrick G, Wilson, Richard H, Harkin, D Paul
Published in Clinical cancer research (15.12.2007)
Published in Clinical cancer research (15.12.2007)
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Defining the molecular evolution of extrauterine high grade serous carcinoma
Beirne, James P, McArt, Darragh G, Roddy, Aideen, McDermott, Clara, Ferris, Jennifer, Buckley, Niamh E, Coulter, Paula, McCabe, Nuala, Eddie, Sharon L, Dunne, Philip D, O'Reilly, Paul, Gilmore, Alan, Feeney, Laura, Ewing, David Lyons, Drapkin, Ronny I, Salto-Tellez, Manuel, Kennedy, Richard D, Harley, Ian J.G, McCluggage, W. Glenn, Mullan, Paul B
Published in Gynecologic oncology (01.11.2019)
Published in Gynecologic oncology (01.11.2019)
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The prognostic significance of the aberrant extremes of p53 immunophenotypes in breast cancer
Boyle, David P, McArt, Darragh G, Irwin, Gareth, Wilhelm-Benartzi, Charlotte S, Lioe, Tong F, Sebastian, Elena, McQuaid, Stephen, Hamilton, Peter W, James, Jacqueline A, Mullan, Paul B, Catherwood, Mark A, Harkin, D Paul, Salto-Tellez, Manuel
Published in Histopathology (01.09.2014)
Published in Histopathology (01.09.2014)
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Pin1 plays a key role in the response to treatment and clinical outcome in triple negative breast cancer
Knowlson, Catherine, Haddock, Paula, Bingham, Victoria, McQuaid, Stephen, Mullan, Paul B., Buckley, Niamh E.
Published in Therapeutic advances in medical oncology (2020)
Published in Therapeutic advances in medical oncology (2020)
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BRCA1, a Potential Predictive Biomarker in the Treatment of Breast Cancer
James, Colin R., Quinn, Jennifer E., Mullan, Paul B., Johnston, Patrick G., Harkin, D. Paul
Published in The oncologist (Dayton, Ohio) (01.02.2007)
Published in The oncologist (Dayton, Ohio) (01.02.2007)
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Investigating Radiotherapy Response in a Novel Syngeneic Model of Prostate Cancer
Haughey, Charles M, Mukherjee, Debayan, Steele, Rebecca E, Popple, Amy, Dura-Perez, Lara, Pickard, Adam, Patel, Mehjabin, Jain, Suneil, Mullan, Paul B, Williams, Rich, Oliveira, Pedro, Buckley, Niamh E, Honeychurch, Jamie, S McDade, Simon, Illidge, Timothy, Mills, Ian G, Eddie, Sharon L
Published in Cancers (29.09.2020)
Published in Cancers (29.09.2020)
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A bespoke target selection tool to guide biomarker discovery in tubo-ovarian cancer
Beirne, James P., Gilmore, Alan, McInerney, Caitríona E., Roddy, Aideen, Glenn McCluggage, W., Harley, Ian J.G., Abdullah Alvi, M., Prise, Kevin M., McArt, Darragh G., Mullan, Paul B.
Published in Computational and structural biotechnology journal (01.01.2022)
Published in Computational and structural biotechnology journal (01.01.2022)
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Journal Article
Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer
Parkes, Eileen E, Walker, Steven M, Taggart, Laura E, McCabe, Nuala, Knight, Laura A, Wilkinson, Richard, McCloskey, Karen D, Buckley, Niamh E, Savage, Kienan I, Salto-Tellez, Manuel, McQuaid, Stephen, Harte, Mary T, Mullan, Paul B, Harkin, D Paul, Kennedy, Richard D
Published in JNCI : Journal of the National Cancer Institute (01.01.2017)
Published in JNCI : Journal of the National Cancer Institute (01.01.2017)
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Journal Article
BRCA1—A good predictive marker of drug sensitivity in breast cancer treatment?
Mullan, Paul B., Gorski, Julia J., Harkin, D. Paul
Published in Biochimica et biophysica acta (01.12.2006)
Published in Biochimica et biophysica acta (01.12.2006)
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Journal Article
BRCA1 and c-Myc associate to transcriptionally repress psoriasin, a DNA damage-inducible gene
Kennedy, Richard D, Gorski, Julia J, Quinn, Jennifer E, Stewart, Gail E, James, Colin R, Moore, Stephen, Mulligan, Karl, Emberley, Ethan D, Lioe, Tong F, Morrison, Patrick J, Mullan, Paul B, Reid, George, Johnston, Patrick G, Watson, Peter H, Harkin, D Paul
Published in Cancer research (Chicago, Ill.) (15.11.2005)
Published in Cancer research (Chicago, Ill.) (15.11.2005)
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Journal Article
BRCA1 and GADD45 mediated G2/M cell cycle arrest in response to antimicrotubule agents
MULLAN, Paul B, QUINN, Jennifer E, MAHESWARAN, Shyamala, LIU, Edison, HABER, Daniel A, JOHNSTON, Patrick G, HARKIN, D. Paul, GILMORE, Paula M, MCWILLIAMS, Stewart, ANDREWS, Heather, GERVIN, Celine, MCCABE, Nuala, MCKENNA, Sarah, WHITE, Pat, SONG, Young-Han
Published in Oncogene (27.09.2001)
Published in Oncogene (27.09.2001)
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Journal Article
BRCA1 Regulates IFN-γ Signaling through a Mechanism Involving the Type I IFNs
Buckley, Niamh E, Hosey, Alison M, Gorski, Julia J, Purcell, James W, Mulligan, Jude M, Harkin, D Paul, Mullan, Paul B
Published in Molecular cancer research (01.03.2007)
Published in Molecular cancer research (01.03.2007)
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Journal Article
Quantification of HER2 heterogeneity in breast cancer-implications for identification of sub-dominant clones for personalised treatment
Buckley, Niamh E, Forde, Claire, McArt, Darragh G, Boyle, David P, Mullan, Paul B, James, Jacqueline A, Maxwell, Perry, McQuaid, Stephen, Salto-Tellez, Manuel
Published in Scientific reports (21.03.2016)
Published in Scientific reports (21.03.2016)
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Journal Article
Liquid biopsy in ovarian cancer: Catching the silent killer before it strikes
Feeney, Laura, Harley, Ian Jg, McCluggage, W Glenn, Mullan, Paul B, Beirne, James P
Published in World journal of clinical oncology (24.11.2020)
Published in World journal of clinical oncology (24.11.2020)
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Journal Article
Identification and Validation of an Anthracycline/ Cyclophosphamide-Based Chemotherapy Response Assay in Breast Cancer
MULLIGAN, Jude M, HILL, Laura A, QUINN, Jennifer E, LINDOR, Noralane M, MULLAN, Paul B, JAMES, Colin R, WALKER, Steven M, KERR, Peter, JAMES, Jacqueline, DAVISON, Timothy S, PROUTSKI, Vitali, SALTO-TELLEZ, Manuel, DEHARO, Steve, JOHNSTON, Patrick G, COUCH, Fergus J, HARKIN, D. Paul, KENNEDY, Richard D, IRWIN, Gareth, BOYLE, David, KEATING, Katherine E, RAJI, Olaide Y, MCDYER, Fionnuala A, O'BRIEN, Eamonn, BYLESJO, Max
Published in JNCI : Journal of the National Cancer Institute (01.01.2014)
Published in JNCI : Journal of the National Cancer Institute (01.01.2014)
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Journal Article
Identification and SAR exploration of a novel series of Legumain inhibitors
Eddie, Sharon L., Gregson, Aaron, Graham, Emma, Burton, Stephanie, Harrison, Timothy, Burden, Roberta, Scott, Christopher J., Mullan, Paul B., Williams, Rich
Published in Bioorganic & medicinal chemistry letters (15.06.2019)
Published in Bioorganic & medicinal chemistry letters (15.06.2019)
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