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mRNA vaccine trafficking and resulting protein expression after intramuscular administration
Hassett, Kimberly J., Rajlic, Ivana Liric, Bahl, Kapil, White, Rebecca, Cowens, Kristen, Jacquinet, Eric, Burke, Kristine E.
Published in Molecular therapy. Nucleic acids (12.03.2024)
Published in Molecular therapy. Nucleic acids (12.03.2024)
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Nose-to-brain siRNA delivery by PEI/PPI-based nanoparticles reduces α-synuclein expression in a Parkinson’s disease mouse model
Feja, Malte, Drath, Isabell, Weiß, Sandra, Ewe, Alexander, Gericke, Birthe, Outeiro, Tiago F., Stefanis, Leonidas, Aigner, Achim, Richter, Franziska
Published in Molecular therapy. Nucleic acids (09.09.2025)
Published in Molecular therapy. Nucleic acids (09.09.2025)
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RNAi delivery mediated by milk extracellular vesicles in colon cancer
Santoro, Jessie, Nuzzo, Silvia, Soricelli, Andrea, Salvatore, Marco, Grimaldi, Anna Maria
Published in Molecular therapy. Nucleic acids (09.09.2025)
Published in Molecular therapy. Nucleic acids (09.09.2025)
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A short peptide for efficient cellular mRNA delivery: A potential application for inducing an immune response
Teko-Agbo, Clémentine Ayélé, Josse, Emilie, Konate, Karidia, Deshayes, Sébastien, de Santa Barbara, Pascal, Faure, Sandrine, Boisguérin, Prisca, Vivès, Eric
Published in Molecular therapy. Nucleic acids (09.09.2025)
Published in Molecular therapy. Nucleic acids (09.09.2025)
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Construction and application of adenoviral vectors
Zhang, Hongbo, Wang, Hongdan, An, Youcai, Chen, Ze
Published in Molecular therapy. Nucleic acids (12.12.2023)
Published in Molecular therapy. Nucleic acids (12.12.2023)
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Manipulating the delivery and immunogenicity of DNA vaccines through the addition of CB[8] to cationic polymers
Sallah, Hadijatou J., Cheesman, Benjamin T., Peeler, David J., Howe, Andrew M., Shattock, Robin J., Coulston, Roger, Tregoning, John S.
Published in Molecular therapy. Nucleic acids (01.06.2025)
Published in Molecular therapy. Nucleic acids (01.06.2025)
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Development of an mRNA replacement therapy for phenylketonuria
Perez-Garcia, Carlos G., Diaz-Trelles, Ramon, Vega, Jerel Boyd, Bao, Yanjie, Sablad, Marciano, Limphong, Patty, Chikamatsu, Simon, Yu, Hailong, Taylor, Wendy, Karmali, Priya P., Tachikawa, Kiyoshi, Chivukula, Padmanabh
Published in Molecular therapy. Nucleic acids (14.06.2022)
Published in Molecular therapy. Nucleic acids (14.06.2022)
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Intratumoral injection of IL-12-encoding mRNA targeted to CSFR1 and PD-L1 exerts potent anti-tumor effects without substantial systemic exposure
Di Trani, Claudia Augusta, Cirella, Assunta, Arrizabalaga, Leire, Alvarez, Maite, Bella, Ángela, Fernandez-Sendin, Myriam, Russo-Cabrera, Joan Salvador, Gomar, Celia, Ardaiz, Nuria, Teijeira, Alvaro, Bolaños, Elixabet, González-Gomariz, José, Otano, Itziar, Aranda, Fernando, Palencia, Belén, Segués, Aina, Huang, Shuyu, van Duijnhoven, Sander M J, van Elsas, Andrea, Melero, Ignacio, Berraondo, Pedro
Published in Molecular therapy. Nucleic acids (12.09.2023)
Published in Molecular therapy. Nucleic acids (12.09.2023)
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Using muscle homing peptide CyPep10 to deliver phosphorodiamidate morpholino oligomers in the mdx mouse
Schneider, Anne-Fleur E., Tanganyika-de Winter, Christa L., Jirka, Silvana M.G., Tan, Xuyu, Thompson, Emily G., Ha, Kristen, Mitra, Anindita, Garcia, Stephanie, Luimes, Marleen, Oliver, Ryan A., Guerlavais, Vincent, Aartsma-Rus, Annemieke
Published in Molecular therapy. Nucleic acids (09.09.2025)
Published in Molecular therapy. Nucleic acids (09.09.2025)
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MVA-HBVac—A novel vaccine vector that allows pan-genotypic targeting of hepatitis B virus by therapeutic vaccination
Kosinska, Anna D., Kächele, Martin, Kerth, Helene A., Mück-Häusl, Martin, Ates Öz, Edanur, Gültan, Merve, Hansen-Palmus, Lea, Sacherl, Julia, Ko, Chunkyu, Festag, Julia, Lehmann, Michael H., Mogler, Carolin, Steiger, Katja, Knolle, Percy A., Bauer, Tanja, Volz, Asisa K., Protzer, Ulrike
Published in Molecular therapy. Nucleic acids (09.09.2025)
Published in Molecular therapy. Nucleic acids (09.09.2025)
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Selective targeting of chemically modified miR-34a to prostate cancer using a small molecule ligand and an endosomal escape agent
Abdelaal, Ahmed M., Sohal, Ikjot S., Iyer, Shreyas G., Sudarshan, Kasireddy, Orellana, Esteban A., Ozcan, Kenan E., dos Santos, Andrea P., Low, Philip S., Kasinski, Andrea L.
Published in Molecular therapy. Nucleic acids (11.06.2024)
Published in Molecular therapy. Nucleic acids (11.06.2024)
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Hair cell-specific Myo15 promoter-mediated gene therapy rescues hearing in DFNB9 mouse model
Wang, Hui, Xun, MengZhao, Tang, Honghai, Zhao, Jingjing, Hu, Shaowei, Zhang, Longlong, Lv, Jun, Wang, Daqi, Chen, Yuxin, Liu, Jianping, Li, Geng-lin, Wang, Wuqing, Shu, Yilai, Li, Huawei
Published in Molecular therapy. Nucleic acids (12.03.2024)
Published in Molecular therapy. Nucleic acids (12.03.2024)
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AAV-mediated delivery of osteoblast/osteoclast-regulating miRNAs for osteoporosis therapy
John, Aijaz Ahmad, Xie, Jun, Yang, Yeon-Suk, Kim, Jung-Min, Lin, Chujiao, Ma, Hong, Gao, Guangping, Shim, Jae-Hyuck
Published in Molecular therapy. Nucleic acids (13.09.2022)
Published in Molecular therapy. Nucleic acids (13.09.2022)
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Poly(β-amino ester)s-based nanovehicles: Structural regulation and gene delivery
Zhang, Jiayu, Cai, Xiaomeng, Dou, Rui, Guo, Chen, Tang, Jiaruo, Hu, Yi, Chen, Hanqing, Chen, Jun
Published in Molecular therapy. Nucleic acids (13.06.2023)
Published in Molecular therapy. Nucleic acids (13.06.2023)
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Nimbolide-based nanomedicine inhibits breast cancer stem-like cells by epigenetic reprogramming of DNMTs-SFRP1-Wnt/β-catenin signaling axis
Mohapatra, Priyanka, Madhulika, Swati, Behera, Somalisa, Singh, Priya, Sa, Pratikshya, Prasad, Punit, Swain, Rajeeb Kumar, Sahoo, Sanjeeb Kumar
Published in Molecular therapy. Nucleic acids (12.12.2023)
Published in Molecular therapy. Nucleic acids (12.12.2023)
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RGC-specific ATF4 and/or CHOP deletion rescues glaucomatous neurodegeneration and visual function
Fang, Fang, Liu, Pingting, Huang, Haoliang, Feng, Xue, Li, Liang, Sun, Yang, Kaufman, Randal J., Hu, Yang
Published in Molecular therapy. Nucleic acids (12.09.2023)
Published in Molecular therapy. Nucleic acids (12.09.2023)
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A taRNA vaccine candidate induces a specific immune response that protects mice against Chikungunya virus infections
Schmidt, Christin, Haefner, Erik, Gerbeth, Julia, Beissert, Tim, Sahin, Ugur, Perkovic, Mario, Schnierle, Barbara S.
Published in Molecular therapy. Nucleic acids (14.06.2022)
Published in Molecular therapy. Nucleic acids (14.06.2022)
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Selection of a novel cell-internalizing RNA aptamer specific for CD22 antigen in B cell acute lymphoblastic leukemia
Ruiz-Ciancio, Dario, Lin, Li-Hsien, Veeramani, Suresh, Barros, Maya N., Sanchez, Diego, Di Bartolo, Ary Lautaro, Masone, Diego, Giangrande, Paloma H., Mestre, María Belén, Thiel, William H.
Published in Molecular therapy. Nucleic acids (12.09.2023)
Published in Molecular therapy. Nucleic acids (12.09.2023)
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Lipid nanoparticle-targeted mRNA formulation as a treatment for ornithine-transcarbamylase deficiency model mice
Yamazaki, Kazuto, Kubara, Kenji, Ishii, Satoko, Kondo, Keita, Suzuki, Yuta, Miyazaki, Takayuki, Mitsuhashi, Kaoru, Ito, Masashi, Tsukahara, Kappei
Published in Molecular therapy. Nucleic acids (12.09.2023)
Published in Molecular therapy. Nucleic acids (12.09.2023)
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