DOCK 6: Impact of new features and current docking performance
Allen, William J., Balius, Trent E., Mukherjee, Sudipto, Brozell, Scott R., Moustakas, Demetri T., Lang, P. Therese, Case, David A., Kuntz, Irwin D., Rizzo, Robert C.
Published in Journal of computational chemistry (05.06.2015)
Published in Journal of computational chemistry (05.06.2015)
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Journal Article
Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase
Snyder, Phillip W, Mecinović, Jasmin, Moustakas, Demetri T, Thomas, Samuel W. III, Harder, Michael, Mack, Eric T, Lockett, Matthew R, Héroux, Annie, Sherman, Woody, Whitesides, George M
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.2011)
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Journal Article
Selective photocrosslinking of functional ligands to antibodies via the conserved nucleotide binding site
Alves, Nathan J, Champion, Matthew M, Stefanick, Jared F, Handlogten, Michael W, Moustakas, Demetri T, Shi, Yunhua, Shaw, Bryan F, Navari, Rudolph M, Kiziltepe, Tanyel, Bilgicer, Basar
Published in Biomaterials (01.07.2013)
Published in Biomaterials (01.07.2013)
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Journal Article
Novel Rapidly Diversifiable Antimicrobial RNA Polymerase Switch Region Inhibitors with Confirmed Mode of Action in Haemophilus influenzae
Buurman, Ed T, Foulk, Melinda A, Gao, Ning, Laganas, Valerie A, McKinney, David C, Moustakas, Demetri T, Rose, Jonathan A, Shapiro, Adam B, Fleming, Paul R
Published in Journal of Bacteriology (01.10.2012)
Published in Journal of Bacteriology (01.10.2012)
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Journal Article
Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA Recognition through a Combination of Rigid Docking and Induced Fit
Pan, Hu, Agarwalla, Sanjay, Moustakas, Demetri T., Finer-Moore, Janet, Stroud, Robert M.
Published in Proceedings of the National Academy of Sciences - PNAS (28.10.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (28.10.2003)
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Journal Article
Unraveling the Interface of Signal Recognition Particle and Its Receptor by Using Chemical Cross-Linking and Tandem Mass Spectrometry
Chu, Feixia, Shan, Shu-ou, Moustakas, Demetri T., Alber, Frank, Egea, Pascal F., Stroud, Robert M., Walter, Peter, Burlingame, Alma L.
Published in Proceedings of the National Academy of Sciences - PNAS (23.11.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (23.11.2004)
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Journal Article
Thermodynamic parameters for the association of fluorinated benzenesulfonamides with bovine carbonic anhydrase II
Krishnamurthy, Vijay M, Bohall, Brooks R, Kim, Chu-Young, Moustakas, Demetri T, Christianson, David W, Whitesides, George M
Published in Chemistry, an Asian journal (08.01.2007)
Published in Chemistry, an Asian journal (08.01.2007)
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Journal Article
RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity across FGFR2 Alterations and Resistance Mutations
Subbiah, Vivek, Sahai, Vaibhav, Maglic, Dejan, Bruderek, Kamil, Touré, B Barry, Zhao, Songping, Valverde, Roberto, O'Hearn, Patrick J, Moustakas, Demetri T, Schönherr, Heike, Gerami-Moayed, Nastaran, Taylor, Alexander M, Hudson, Brandi M, Houde, Damian J, Pal, Debjani, Foster, Lindsey, Gunaydin, Hakan, Ayaz, Pelin, Sharon, Dina A, Goyal, Lipika, Schram, Alison M, Kamath, Suneel, Sherwin, Cori Ann, Schmidt-Kittler, Oleg, Jen, Kai Yu, Ricard, Fabien, Wolf, Beni B, Shaw, David E, Bergstrom, Donald A, Watters, James, Casaletto, Jessica B
Published in Cancer discovery (06.09.2023)
Published in Cancer discovery (06.09.2023)
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Journal Article
Discovery of lirafugratinib (RLY-4008), a highly selective irreversible small-molecule inhibitor of FGFR2
Schönherr, Heike, Ayaz, Pelin, Taylor, Alexander M, Casaletto, Jessica B, Touré, B Barry, Moustakas, Demetri T, Hudson, Brandi M, Valverde, Roberto, Zhao, Songping, O'Hearn, Patrick J, Foster, Lindsey, Sharon, Dina A, Garfinkle, Sam, Giordanetto, Fabrizio, Lescarbeau, André, Kurukulasuriya, Ravi, Gerami-Moayed, Nastaran, Maglic, Dejan, Bruderek, Kamil, Naik, Gaauri, Gunaydin, Hakan, Mader, Mary M, Boezio, Alessandro A, McLean, Thomas H, Chen, Rongfeng, Wang, Yanxia, Shaw, David E, Watters, James, Bergstrom, Donald A
Published in Proceedings of the National Academy of Sciences - PNAS (06.02.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (06.02.2024)
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Journal Article
Dependence of Avidity on Linker Length for a Bivalent Ligand–Bivalent Receptor Model System
Mack, Eric T, Snyder, Phillip W, Perez-Castillejos, Raquel, Bilgiçer, Başar, Moustakas, Demetri T, Butte, Manish J, Whitesides, George M
Published in Journal of the American Chemical Society (11.01.2012)
Published in Journal of the American Chemical Society (11.01.2012)
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Journal Article
Acetylation of Surface Lysine Groups of a Protein Alters the Organization and Composition of Its Crystal Contacts
Kang, Kyungtae, Choi, Jeong-Mo, Fox, Jerome M, Snyder, Phillip W, Moustakas, Demetri T, Whitesides, George M
Published in The journal of physical chemistry. B (14.07.2016)
Published in The journal of physical chemistry. B (14.07.2016)
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Journal Article
Increasing the Net Charge and Decreasing the Hydrophobicity of Bovine Carbonic Anhydrase Decreases the Rate of Denaturation with Sodium Dodecyl Sulfate
Gudiksen, Katherine L., Gitlin, Irina, Moustakas, Demetri T., Whitesides, George M.
Published in Biophysical journal (01.07.2006)
Published in Biophysical journal (01.07.2006)
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Journal Article
Fluoroalkyl and Alkyl Chains Have Similar Hydrophobicities in Binding to the “Hydrophobic Wall” of Carbonic Anhydrase
Mecinović, Jasmin, Snyder, Phillip W, Mirica, Katherine A, Bai, Serena, Mack, Eric T, Kwant, Richard L, Moustakas, Demetri T, Héroux, Annie, Whitesides, George M
Published in Journal of the American Chemical Society (07.09.2011)
Published in Journal of the American Chemical Society (07.09.2011)
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Journal Article
Preclinical pharmacokinetic/pharmacodynamic models to predict synergistic effects of co-administered anti-cancer agents
Goteti, Kosalaram, Edwin Garner, C, Utley, Lucas, Dai, Jing, Ashwell, Susan, Moustakas, Demetri T, Gönen, Mithat, Schwartz, Gary K, Kern, Steven E, Zabludoff, Sonya, Brassil, Patrick J
Published in Cancer chemotherapy and pharmacology (01.07.2010)
Published in Cancer chemotherapy and pharmacology (01.07.2010)
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Journal Article
A Synthetic Trivalent Hapten that Aggregates anti-2,4-DNP IgG into Bicyclic Trimers
Bilgiçer, Başar, Moustakas, Demetri T, Whitesides, George M
Published in Journal of the American Chemical Society (28.03.2007)
Published in Journal of the American Chemical Society (28.03.2007)
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Journal Article
Design of a Heterobivalent Ligand to Inhibit IgE Clustering on Mast Cells
Handlogten, Michael W., Kiziltepe, Tanyel, Moustakas, Demetri T., Bilgiçer, Başar
Published in Chemistry & biology (23.09.2011)
Published in Chemistry & biology (23.09.2011)
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Journal Article
Taking Charge of Proteins: From Neurodegeneration to Industrial Biotechnology
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Book Chapter
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