Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss
Lucas, Sébastien, Omata, Yasunori, Hofmann, Jörg, Böttcher, Martin, Iljazovic, Aida, Sarter, Kerstin, Albrecht, Olivia, Schulz, Oscar, Krishnacoumar, Brenda, Krönke, Gerhard, Herrmann, Martin, Mougiakakos, Dimitrios, Strowig, Till, Schett, Georg, Zaiss, Mario M.
Published in Nature communications (04.01.2018)
Published in Nature communications (04.01.2018)
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Journal Article
The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer
Krebs, Angela M., Mitschke, Julia, Lasierra Losada, María, Schmalhofer, Otto, Boerries, Melanie, Busch, Hauke, Boettcher, Martin, Mougiakakos, Dimitrios, Reichardt, Wilfried, Bronsert, Peter, Brunton, Valerie G., Pilarsky, Christian, Winkler, Thomas H., Brabletz, Simone, Stemmler, Marc P., Brabletz, Thomas
Published in Nature cell biology (01.05.2017)
Published in Nature cell biology (01.05.2017)
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Journal Article
Polyol Pathway Links Glucose Metabolism to the Aggressiveness of Cancer Cells
Schwab, Annemarie, Siddiqui, Aarif, Vazakidou, Maria Eleni, Napoli, Francesca, Böttcher, Martin, Menchicchi, Bianca, Raza, Umar, Saatci, Özge, Krebs, Angela M, Ferrazzi, Fulvia, Rapa, Ida, Dettmer-Wilde, Katja, Waldner, Maximilian J, Ekici, Arif B, Rasheed, Suhail Ahmed Kabeer, Mougiakakos, Dimitrios, Oefner, Peter J, Sahin, Ozgur, Volante, Marco, Greten, Florian R, Brabletz, Thomas, Ceppi, Paolo
Published in Cancer research (Chicago, Ill.) (01.04.2018)
Published in Cancer research (Chicago, Ill.) (01.04.2018)
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Journal Article
IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation
Faas, Maria, Ipseiz, Natacha, Ackermann, Jochen, Culemann, Stephan, Grüneboom, Anika, Schröder, Fenja, Rothe, Tobias, Scholtysek, Carina, Eberhardt, Martin, Böttcher, Martin, Kirchner, Philipp, Stoll, Cornelia, Ekici, Arif, Fuchs, Maximilian, Kunz, Meik, Weigmann, Benno, Wirtz, Stefan, Lang, Roland, Hofmann, Joerg, Vera, Julio, Voehringer, David, Michelucci, Alessandro, Mougiakakos, Dimitrios, Uderhardt, Stefan, Schett, Georg, Krönke, Gerhard
Published in Immunity (Cambridge, Mass.) (09.11.2021)
Published in Immunity (Cambridge, Mass.) (09.11.2021)
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Journal Article
Immature Immunosuppressive CD14+HLA-DR-/low Cells in Melanoma Patients Are Stat3hi and Overexpress CD80, CD83, and DC-Sign
POSCHKE, Isabel, MOUGIAKAKOS, Dimitrios, HANSSON, Johan, MASUCCI, Giuseppe V, KIESSLING, Rolf
Published in Cancer research (Chicago, Ill.) (01.06.2010)
Published in Cancer research (Chicago, Ill.) (01.06.2010)
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β2-microglobulin triggers NLRP3 inflammasome activation in tumor-associated macrophages to promote multiple myeloma progression
Hofbauer, Daniel, Mougiakakos, Dimitrios, Broggini, Luca, Zaiss, Mario, Büttner-Herold, Maike, Bach, Christian, Spriewald, Bernd, Neumann, Frank, Bisht, Savita, Nolting, Jens, Zeiser, Robert, Hamarsheh, Shaima’a, Eberhardt, Martin, Vera, Julio, Visentin, Cristina, De Luca, Chiara Maria Giulia, Moda, Fabio, Haskamp, Stefan, Flamann, Cindy, Böttcher, Martin, Bitterer, Katrin, Völkl, Simon, Mackensen, Andreas, Ricagno, Stefano, Bruns, Heiko
Published in Immunity (Cambridge, Mass.) (10.08.2021)
Published in Immunity (Cambridge, Mass.) (10.08.2021)
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Journal Article
Mitochondrial metabolism contributes to oxidative stress and reveals therapeutic targets in chronic lymphocytic leukemia
Jitschin, Regina, Hofmann, Andreas D., Bruns, Heiko, Gießl, Andreas, Bricks, Juliane, Berger, Jana, Saul, Domenica, Eckart, Michael J., Mackensen, Andreas, Mougiakakos, Dimitrios
Published in Blood (24.04.2014)
Published in Blood (24.04.2014)
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D-2-hydroxyglutarate interferes with HIF-1α stability skewing T-cell metabolism towards oxidative phosphorylation and impairing Th17 polarization
Böttcher, Martin, Renner, Kathrin, Berger, Raffaela, Mentz, Kristin, Thomas, Simone, Cardenas-Conejo, Zugey Elizabeth, Dettmer, Katja, Oefner, Peter J., Mackensen, Andreas, Kreutz, Marina, Mougiakakos, Dimitrios
Published in Oncoimmunology (03.07.2018)
Published in Oncoimmunology (03.07.2018)
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The CAR-HEMATOTOX risk-stratifies patients for severe infections and disease progression after CD19 CAR-T in R/R LBCL
Rejeski, Kai, Perez, Ariel, Iacoboni, Gloria, Penack, Olaf, Bücklein, Veit, Jentzsch, Liv, Mougiakakos, Dimitrios, Johnson, Grace, Arciola, Brian, Carpio, Cecilia, Blumenberg, Viktoria, Hoster, Eva, Bullinger, Lars, Locke, Frederick L, von Bergwelt-Baildon, Michael, Mackensen, Andreas, Bethge, Wolfgang, Barba, Pere, Jain, Michael D, Subklewe, Marion
Published in Journal for immunotherapy of cancer (01.05.2022)
Published in Journal for immunotherapy of cancer (01.05.2022)
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TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection
Schleicher, Ulrike, Paduch, Katrin, Debus, Andrea, Obermeyer, Stephanie, König, Till, Kling, Jessica C., Ribechini, Eliana, Dudziak, Diana, Mougiakakos, Dimitrios, Murray, Peter J., Ostuni, Renato, Körner, Heinrich, Bogdan, Christian
Published in Cell reports (Cambridge) (03.05.2016)
Published in Cell reports (Cambridge) (03.05.2016)
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Journal Article
Stromal cell–mediated glycolytic switch in CLL cells involves Notch-c-Myc signaling
Jitschin, Regina, Braun, Martina, Qorraj, Mirjeta, Saul, Domenica, Le Blanc, Katarina, Zenz, Thorsten, Mougiakakos, Dimitrios
Published in Blood (28.05.2015)
Published in Blood (28.05.2015)
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Journal Article
Metabolic reprogramming of osteoclasts represents a therapeutic target during the treatment of osteoporosis
Taubmann, Jule, Krishnacoumar, Brenda, Böhm, Christina, Faas, Maria, Müller, Dorothea I. H., Adam, Susanne, Stoll, Cornelia, Böttcher, Martin, Mougiakakos, Dimitrios, Sonnewald, Uwe, Hofmann, Jörg, Schett, Georg, Krönke, Gerhard, Scholtysek, Carina
Published in Scientific reports (03.12.2020)
Published in Scientific reports (03.12.2020)
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Journal Article
T-Cell Metabolism in Graft Versus Host Disease
Karl, Franziska, Hudecek, Michael, Berberich-Siebelt, Friederike, Mackensen, Andreas, Mougiakakos, Dimitrios
Published in Frontiers in immunology (29.10.2021)
Published in Frontiers in immunology (29.10.2021)
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Journal Article
The metabolic profile of reconstituting T-cells, NK-cells, and monocytes following autologous stem cell transplantation and its impact on outcome
Richter, Silja, Böttcher, Martin, Völkl, Simon, Mackensen, Andreas, Ullrich, Evelyn, Jacobs, Benedikt, Mougiakakos, Dimitrios
Published in Scientific reports (06.07.2022)
Published in Scientific reports (06.07.2022)
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Journal Article
A defined metabolic state in pre B cells governs B-cell development and is counterbalanced by Swiprosin-2/EFhd1
Stein, Merle, Dütting, Sebastian, Mougiakakos, Dimitrios, Bösl, Michael, Fritsch, Kristin, Reimer, Dorothea, Urbanczyk, Sophia, Steinmetz, Tobit, Schuh, Wolfgang, Bozec, Aline, Winkler, Thomas H, Jäck, Hans-Martin, Mielenz, Dirk
Published in Cell death and differentiation (01.07.2017)
Published in Cell death and differentiation (01.07.2017)
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Journal Article
Linking Immunoevasion and Metabolic Reprogramming in B-Cell–Derived Lymphomas
Böttcher, Martin, Baur, Rebecca, Stoll, Andrej, Mackensen, Andreas, Mougiakakos, Dimitrios
Published in Frontiers in oncology (05.11.2020)
Published in Frontiers in oncology (05.11.2020)
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