Identification of Three Residues Essential for 5-Hydroxytryptamine 2A-Metabotropic Glutamate 2 (5-HT2A·mGlu2) Receptor Heteromerization and Its Psychoactive Behavioral Function
Moreno, José L., Muguruza, Carolina, Umali, Adrienne, Mortillo, Steven, Holloway, Terrell, Pilar-Cuéllar, Fuencisla, Mocci, Giuseppe, Seto, Jeremy, Callado, Luis F., Neve, Rachael L., Milligan, Graeme, Sealfon, Stuart C., López-Giménez, Juan F., Meana, J. Javier, Benson, Deanna L., González-Maeso, Javier
Published in The Journal of biological chemistry (28.12.2012)
Published in The Journal of biological chemistry (28.12.2012)
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The antiangiogenic activity in xenograft models of brivanib, a dual inhibitor of vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 kinases
Bhide, Rajeev S, Lombardo, Louis J, Hunt, John T, Cai, Zhen-Wei, Barrish, Joel C, Galbraith, Susan, Jeyaseelan, Sr, Robert, Mortillo, Steven, Wautlet, Barri S, Krishnan, Bala, Kukral, Daniel, Malone, Harold, Lewin, Anne C, Henley, Benjamin J, Fargnoli, Joseph
Published in Molecular cancer therapeutics (01.02.2010)
Published in Molecular cancer therapeutics (01.02.2010)
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Compensatory redistribution of neuroligins and N-cadherin following deletion of synaptic β1-integrin
Mortillo, Steven, Elste, Alice, Ge, Yongchao, Patil, Shekhar B., Hsiao, Kuangfu, Huntley, George W., Davis, Ronald L., Benson, Deanna L.
Published in Journal of comparative neurology (1911) (15.06.2012)
Published in Journal of comparative neurology (1911) (15.06.2012)
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The granin VGF promotes genesis of secretory vesicles, and regulates circulating catecholamine levels and blood pressure
Fargali, Samira, Garcia, Angelo L, Sadahiro, Masato, Jiang, Cheng, Janssen, William G, Lin, Wei-Jye, Cogliani, Valeria, Elste, Alice, Mortillo, Steven, Cero, Cheryl, Veitenheimer, Britta, Graiani, Gallia, Pasinetti, Giulio M, Mahata, Sushil K, Osborn, John W, Huntley, George W, Phillips, Greg R, Benson, Deanna L, Bartolomucci, Alessandro, Salton, Stephen R
Published in The FASEB journal (01.05.2014)
Published in The FASEB journal (01.05.2014)
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Discovery and Preclinical Studies of (R)-1-(4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-5- methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan- 2-ol (BMS-540215), an In Vivo Active Potent VEGFR-2 Inhibitor
Bhide, Rajeev S, Cai, Zhen-Wei, Zhang, Yong-Zheng, Qian, Ligang, Wei, Donna, Barbosa, Stephanie, Lombardo, Louis J, Borzilleri, Robert M, Zheng, Xiaoping, Wu, Laurence I, Barrish, Joel C, Kim, Soong-Hoon, Leavitt, Kenneth, Mathur, Arvind, Leith, Leslie, Chao, Sam, Wautlet, Barri, Mortillo, Steven, Jeyaseelan, Robert, Kukral, Daniel, Hunt, John T, Kamath, Amrita, Fura, Aberra, Vyas, Viral, Marathe, Punit, D'Arienzo, Celia, Derbin, George, Fargnoli, Joseph
Published in Journal of medicinal chemistry (06.04.2006)
Published in Journal of medicinal chemistry (06.04.2006)
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Compensatory redistribution of neuroligins and N-cadherin following deletion of synaptic [beta]1-integrin
Mortillo, Steven, Elste, Alice, Ge, Yongchao, Patil, Shekhar B, Hsiao, Kuangfu, Huntley, George W, Davis, Ronald L, Benson, Deanna L
Published in Journal of comparative neurology (1911) (15.06.2012)
Published in Journal of comparative neurology (1911) (15.06.2012)
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Discovery of the Pyrrolo[2,1-f][1,2,4]triazine Nucleus as a New Kinase Inhibitor Template
Hunt, John T, Mitt, Toomas, Borzilleri, Robert, Gullo-Brown, Johnni, Fargnoli, Joseph, Fink, Brian, Han, Wen-Ching, Mortillo, Steven, Vite, Gregory, Wautlet, Barri, Wong, Tai, Yu, Chiang, Zheng, Xiaoping, Bhide, Rajeev
Published in Journal of medicinal chemistry (29.07.2004)
Published in Journal of medicinal chemistry (29.07.2004)
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Synthesis, SAR, and Evaluation of 4-[2,4-Difluoro-5-(cyclopropylcarbamoyl)phenylamino]pyrrolo[2,1- f][1,2,4]triazine-based VEGFR-2 kinase inhibitors
Cai, Zhen-wei, Wei, Donna, Borzilleri, Robert M., Qian, Ligang, Kamath, Amrita, Mortillo, Steven, Wautlet, Barri, Henley, Benjamin J., Jeyaseelan, Robert, Tokarski, John, Hunt, John T., Bhide, Rajeev S., Fargnoli, Joseph, Lombardo, Louis J.
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
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Targeted Disruption of the mZP3 Gene Results in Production of Eggs Lacking a Zona Pellucida and Infertility in Female Mice
Liu, Chengyu, Litscher, Eveline S., Mortillo, Steven, Sakai, Yutaka, Kinloch, Ross A., Stewart, Colin L., Wassarman, Paul M.
Published in Proceedings of the National Academy of Sciences - PNAS (28.05.1996)
Published in Proceedings of the National Academy of Sciences - PNAS (28.05.1996)
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Discovery and preclinical studies of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)- N-(2-methyl-1 H-pyrrolo[2,3- b]pyridin-5-yl)pyrrolo[2,1- f][1,2,4]triazin-4-amine (BMS-645737), an in vivo active potent VEGFR-2 inhibitor
Ruel, Réjean, Thibeault, Carl, L’Heureux, Alexandre, Martel, Alain, Cai, Zhen-Wei, Wei, Donna, Qian, Ligang, Barrish, Joel C., Mathur, Arvind, D’Arienzo, Celia, Hunt, John T., Kamath, Amrita, Marathe, Punit, Zhang, Yueping, Derbin, George, Wautlet, Barri, Mortillo, Steven, Jeyaseelan, Robert, Henley, Benjamin, Tejwani, Ravindra, Bhide, Rajeev S., Trainor, George L., Fargnoli, Joseph, Lombardo, Louis J.
Published in Bioorganic & medicinal chemistry letters (01.05.2008)
Published in Bioorganic & medicinal chemistry letters (01.05.2008)
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Synthesis and SAR of 4-(3-hydroxyphenylamino)pyrrolo[2,1- f][1,2,4]triazine based VEGFR-2 kinase inhibitors
Borzilleri, Robert M., Cai, Zhen-wei, Ellis, Christopher, Fargnoli, Joseph, Fura, Aberra, Gerhardt, Tracy, Goyal, Bindu, Hunt, John T., Mortillo, Steven, Qian, Ligang, Tokarski, John, Vyas, Viral, Wautlet, Barri, Zheng, Xioping, Bhide, Rajeev S.
Published in Bioorganic & medicinal chemistry letters (01.03.2005)
Published in Bioorganic & medicinal chemistry letters (01.03.2005)
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Erratum. The granin VGF promotes genesis of secretory vesicles, and regulates circulating catecholamine levels and blood pressure
Fargali, Samira, Garcia, Angelo L, Sadahiro, Masato, Jiang, Cheng, Janssen, William G, Lin, Wei-Jye, Cogliani, Valeria, Elste, Alice, Mortillo, Steven, Cero, Cheryl, Veitenheimer, Britta, Graiani, Gallia, Pasinetti, Giulio M, Mahata, Sushil K, Osborn, John W, Huntley, George W, Phillips, Greg R, Benson, Deanna L, Bartolomucci, Alessandro, Salton, Stephen R
Published in The FASEB journal (01.06.2015)
Published in The FASEB journal (01.06.2015)
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Synthesis, SAR, and Evaluation of 4-[2,4-Difluoro-5- (cyclopropylcarbamoyl)phenylamino]pyrrolo[2,1-f][1,2,4]triazine-ba sed VEGFR-2 kinase inhibitors
Cai, Zhen-Wei, Wei, Donna, Borzilleri, Robert M, Qian, Ligang, Kamath, Amrita, Mortillo, Steven, Wautlet, Barri, Henley, Benjamin J, Sr., Robert Jeyaseelan, Tokarski, John, Hunt, John T, Bhide, Rajeev S, Fargnoli, Joseph, Lombardo, Louis J
Published in Bioorganic & medicinal chemistry (01.02.2008)
Published in Bioorganic & medicinal chemistry (01.02.2008)
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Discovery and preclinical studies of (R)-1-(4-(4-fluoro-2-methyl- 1H-indol-5-yloxy)-5-methylpyrrolo[2,1-/][1,2,4]triazin-6-yloxy)propan2-ol (BMS-540215), an in vivo active potent VEGFR-2 inhibitor
BHIDE, Rajeev S, CAI, Zhen-Wei, BARRISH, Joel C, KIM, Soong-Hoon, LEAVITT, Kenneth, MATHUR, Arvind, LEITH, Leslie, CHAO, Sam, WAUTLET, Barri, MORTILLO, Steven, JEYASEELAN, Robert, KUKRAL, Daniel, ZHANG, Yong-Zheng, HUNT, John T, KAMATH, Amrita, FURA, Aberra, VYAS, Viral, MARATHE, Punit, D'ARIENZO, Celia, DERBIN, George, FARGNOLI, Joseph, LIGANG QIAN, WEI, Donna, BARBOSA, Stephanie, LOMBARDO, Louis J, BORZILLERI, Robert M, XIAOPING ZHENG, WU, Laurence I
Published in Journal of medicinal chemistry (2006)
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Published in Journal of medicinal chemistry (2006)
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An Upstream Region of the Mouse ZP3 Gene Directs Expression of Firefly Luciferase Specifically to Growing Oocytes in Transgenic Mice
Lira, Sergio A., Kinloch, Ross A., Mortillo, Steven, Wassarman, Paul M.
Published in Proceedings of the National Academy of Sciences - PNAS (01.09.1990)
Published in Proceedings of the National Academy of Sciences - PNAS (01.09.1990)
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