Macrocyclic glycopeptide chiral selectors bonded to core-shell particles enables enantiopurity analysis of the entire verubecestat synthetic route
Barhate, Chandan L., Lopez, Diego A., Makarov, Alexey A., Bu, Xiaodong, Morris, William J., Lekhal, Azzeddine, Hartman, Robert, Armstrong, Daniel W., Regalado, Erik L.
Published in Journal of Chromatography A (02.03.2018)
Published in Journal of Chromatography A (02.03.2018)
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Journal Article
A Next Generation Synthesis of BACE1 Inhibitor Verubecestat (MK‑8931)
Thaisrivongs, David A, Morris, William J, Tan, Lushi, Song, Zhiguo J, Lyons, Thomas W, Waldman, Jacob H, Naber, John R, Chen, Wenyong, Chen, Lu, Zhang, Baoyun, Yang, Jun
Published in Organic letters (16.03.2018)
Published in Organic letters (16.03.2018)
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Journal Article
Synthesis of (−)-Okilactomycin by a Prins-Type Fragment-Assembly Strategy
Tenenbaum, Jason M., Morris, William J., Custar, Daniel W., Scheidt, Karl A.
Published in Angewandte Chemie International Edition (20.06.2011)
Published in Angewandte Chemie International Edition (20.06.2011)
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Journal Article
Engineered Ribosyl-1-Kinase Enables Concise Synthesis of Molnupiravir, an Antiviral for COVID-19
McIntosh, John A, Benkovics, Tamas, Silverman, Steven M, Huffman, Mark A, Kong, Jongrock, Maligres, Peter E, Itoh, Tetsuji, Yang, Hao, Verma, Deeptak, Pan, Weilan, Ho, Hsing-I, Vroom, Jonathan, Knight, Anders M, Hurtak, Jessica A, Klapars, Artis, Fryszkowska, Anna, Morris, William J, Strotman, Neil A, Murphy, Grant S, Maloney, Kevin M, Fier, Patrick S
Published in ACS central science (22.12.2021)
Published in ACS central science (22.12.2021)
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Journal Article
Radical trimodality therapy for patients with locally advanced bladder cancer: The British Columbia Cancer Agency experience
Baxter, Emily, B.Sc, Dennis, Kristopher, M.D., F.R.C.P.C, Kollmannsberger, Christian, M.D., F.R.C.P.C, Black, Peter, M.D., F.R.C.P.C, Attwell, Andrew, M.D., F.R.C.P.C, Morris, William J., M.D., F.R.C.P.C, Tyldesley, Scott, M.D., M.P.A., F.R.C.P.C
Published in Urologic oncology (01.02.2015)
Published in Urologic oncology (01.02.2015)
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Journal Article
Learning-Based Multi-Label Segmentation of Transrectal Ultrasound Images for Prostate Brachytherapy
Nouranian, Saman, Ramezani, Mahdi, Spadinger, Ingrid, Morris, William J., Salcudean, Septimu E., Abolmaesumi, Purang
Published in IEEE transactions on medical imaging (01.03.2016)
Published in IEEE transactions on medical imaging (01.03.2016)
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Journal Article
Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan
Cheung‐Lee, Wai Ling, Kolev, Joshua N., McIntosh, John A., Gil, Agnieszka A., Pan, Weilan, Xiao, Li, Velásquez, Juan E., Gangam, Rekha, Winston, Matthew S., Li, Shasha, Abe, Kotoe, Alwedi, Embarek, Dance, Zachary E. X., Fan, Haiyang, Hiraga, Kaori, Kim, Jungchul, Kosjek, Birgit, Le, Diane N., Marzijarani, Nastaran Salehi, Mattern, Keith, McMullen, Jonathan P., Narsimhan, Karthik, Vikram, Ajit, Wang, Wei, Yan, Jia‐Xuan, Yang, Rong‐Sheng, Zhang, Victoria, Zhong, Wendy, DiRocco, Daniel A., Morris, William J., Murphy, Grant S., Maloney, Kevin M.
Published in Angewandte Chemie International Edition (22.03.2024)
Published in Angewandte Chemie International Edition (22.03.2024)
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Journal Article
Development of a Robust Manufacturing Route for Molnupiravir, an Antiviral for the Treatment of COVID-19
Fier, Patrick S., Xu, Yingju, Poirier, Marc, Brito, Gilmar, Zheng, Michelle, Bade, Rachel, Sirota, Eric, Stone, Kevin, Tan, Lushi, Humphrey, Guy R., Chang, Darryl, Bothe, Jameson, Zhang, Yongqian, Bernardoni, Frank, Castro, Steve, Zompa, Michael A., Taylor, Jerry, Sirk, Kevin M., Diaz-Santana, Anthony, Diribe, Ike, Emerson, Khateeta M., Krishnamurthi, Bharath, Zhao, Ralph, Ward, Michael, Xiao, Chengqian, Ouyand, Honggui, Zhan, Jianfeng, Morris, William J.
Published in Organic process research & development (17.12.2021)
Published in Organic process research & development (17.12.2021)
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Journal Article
Semi-automatic segmentation for prostate interventions
Sara Mahdavi, S., Chng, Nick, Spadinger, Ingrid, Morris, William J., Salcudean, Septimiu E.
Published in Medical image analysis (01.04.2011)
Published in Medical image analysis (01.04.2011)
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Journal Article
Synthesis of the γ‑Secretase Modulator MK-8428
Miller, Steven P, Morris, William J, Orr, Robert K, Eckert, Jeffrey, Milan, Jay, Maust, Mathew, Cowden, Cameron, Cui, Jian
Published in Journal of organic chemistry (17.03.2017)
Published in Journal of organic chemistry (17.03.2017)
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Journal Article
Statistical Biomechanical Surface Registration: Application to MR-TRUS Fusion for Prostate Interventions
Khallaghi, Siavash, Sanchez, C. Antonio, Rasoulian, Abtin, Nouranian, Saman, Romagnoli, Cesare, Abdi, Hamidreza, Chang, Silvia D., Black, Peter C., Goldenberg, Larry, Morris, William J., Spadinger, Ingrid, Fenster, Aaron, Ward, Aaron, Fels, Sidney, Abolmaesumi, Purang
Published in IEEE transactions on medical imaging (01.12.2015)
Published in IEEE transactions on medical imaging (01.12.2015)
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Journal Article
Highly Diastereoselective Synthesis of a HCV NS5B Nucleoside Polymerase Inhibitor
Zhong, Yong-Li, Cleator, Ed, Liu, Zhijian, Yin, Jianguo, Morris, William J, Alam, Mahbub, Bishop, Brian, Dumas, Aaron M, Edwards, John, Goodyear, Adrian, Mullens, Peter, Song, Zhiguo Jake, Shevlin, Michael, Thaisrivongs, David A, Li, Hongming, Sherer, Edward C, Cohen, Ryan D, Yin, Jingjun, Tan, Lushi, Yasuda, Nobuyoshi, Limanto, John, Davies, Antony, Campos, Kevin R
Published in Journal of organic chemistry (19.04.2019)
Published in Journal of organic chemistry (19.04.2019)
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Journal Article
Characterization of a Unique Co-crystal of the BACE1 Inhibitor Verubecestat and a Reaction Intermediate: Implications for the Development of a Commercial Manufacturing Process
Artino, Laura, Varsolona, Richard, Brunskill, Andrew P. J, Morris, William J, Thaisrivongs, David A, Waldman, Jacob H, Lyons, Thomas W, Xu, Yanke
Published in Organic process research & development (16.03.2018)
Published in Organic process research & development (16.03.2018)
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Journal Article
Stereoselective Addition of 2‑Phenyloxazol-4-yl Trifluoromethanesulfonate to N‑Sulfinyl Imines: Application to the Synthesis of the HCV Protease Inhibitor Boceprevir
Morris, William J, Muppalla, Kiran K, Cowden, Cameron, Ball, Richard G
Published in Journal of organic chemistry (18.01.2013)
Published in Journal of organic chemistry (18.01.2013)
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Journal Article