Combining BH3-mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemia
Moujalled, Donia M., Pomilio, Giovanna, Ghiurau, Corina, Ivey, Adam, Salmon, Jessica, Rijal, Sewa, Macraild, Sarah, Zhang, Lan, Teh, Tse-Chieh, Tiong, Ing-Soo, Lan, Ping, Chanrion, Maia, Claperon, Audrey, Rocchetti, Francesca, Zichi, Adrien, Kraus-Berthier, Laurence, Wang, Youzhen, Halilovic, Ensar, Morris, Erick, Colland, Frédéric, Segal, David, Huang, David, Roberts, Andrew W., Maragno, Ana Leticia, Lessene, Guillaume, Geneste, Olivier, Wei, Andrew H.
Published in Leukemia (01.04.2019)
Published in Leukemia (01.04.2019)
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Journal Article
Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors
Morris, Erick J, Jha, Sharda, Restaino, Clifford R, Dayananth, Priya, Zhu, Hugh, Cooper, Alan, Carr, Donna, Deng, Yongi, Jin, Weihong, Black, Stuart, Long, Brian, Liu, Jenny, Dinunzio, Edward, Windsor, William, Zhang, Rumin, Zhao, Shuxia, Angagaw, Minilik H, Pinheiro, Elaine M, Desai, Jagdish, Xiao, Li, Shipps, Gerald, Hruza, Alan, Wang, James, Kelly, Joe, Paliwal, Sunil, Gao, Xiaolei, Babu, Boga Sobhana, Zhu, Liang, Daublain, Pierre, Zhang, Ling, Lutterbach, Bart A, Pelletier, Marc R, Philippar, Ulrike, Siliphaivanh, Phieng, Witter, David, Kirschmeier, Paul, Bishop, W Robert, Hicklin, Daniel, Gilliland, D Gary, Jayaraman, Lata, Zawel, Leigh, Fawell, Stephen, Samatar, Ahmed A
Published in Cancer discovery (01.07.2013)
Published in Cancer discovery (01.07.2013)
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Journal Article
BH3 profiling as pharmacodynamic biomarker for the activity of BH3 mimetics
Pan, Rongqing Aaron, Wang, Youzhen, Qiu, Shumei, Villalobos-Ortiz, Mariana, Ryan, Jeremy, Morris, Erick, Halilovic, Ensar, Letai, Anthony
Published in Haematologica (Roma) (01.04.2024)
Published in Haematologica (Roma) (01.04.2024)
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Journal Article
E2F1 represses β-catenin transcription and is antagonized by both pRB and CDK8
Morris, Erick J., Ji, Jun-Yuan, Yang, Fajun, Di Stefano, Luisa, Herr, Anabel, Moon, Nam-Sung, Kwon, Eun-Jeong, Haigis, Kevin M., Näär, Anders M., Dyson, Nicholas J.
Published in Nature (London) (25.09.2008)
Published in Nature (London) (25.09.2008)
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Journal Article
Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance
Cotton, Jennifer L., Estrada Diez, Javier, Sagar, Vivek, Chen, Julie, Piquet, Michelle, Alford, John, Song, Youngchul, Li, Xiaoyan, Riester, Markus, DiMare, Matthew T., Schumacher, Katja, Boulay, Gaylor, Sprouffske, Kathleen, Fan, Lin, Burks, Tyler, Mansur, Leandra, Wagner, Joel, Bhang, Hyo-eun C., Iartchouk, Oleg, Reece-Hoyes, John, Morris, Erick J., Hammerman, Peter S., Ruddy, David A., Korn, Joshua M., Engelman, Jeffrey A., Niederst, Matthew J.
Published in Cancer research (Chicago, Ill.) (01.11.2023)
Published in Cancer research (Chicago, Ill.) (01.11.2023)
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Journal Article
Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo
Morris, Erick J, Michaud, William A, Ji, Jun-Yuan, Moon, Nam-Sung, Rocco, James W, Dyson, Nicholas J
Published in PLoS genetics (01.11.2006)
Published in PLoS genetics (01.11.2006)
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Journal Article
Dissecting Therapeutic Resistance to ERK Inhibition
Jha, Sharda, Morris, Erick J, Hruza, Alan, Mansueto, My Sam, Schroeder, Gottfried K, Arbanas, Jaren, McMasters, Daniel, Restaino, Clifford R, Dayananth, Priya, Black, Stuart, Elsen, Nathaniel L, Mannarino, Anthony, Cooper, Alan, Fawell, Stephen, Zawel, Leigh, Jayaraman, Lata, Samatar, Ahmed A
Published in Molecular cancer therapeutics (01.04.2016)
Published in Molecular cancer therapeutics (01.04.2016)
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Journal Article
Evaluating TBK1 as a therapeutic target in cancers with activated IRF3
Muvaffak, Asli, Pan, Qi, Yan, Haiyan, Fernandez, Rafael, Lim, Jongwon, Dolinski, Brian, Nguyen, Thi T, Strack, Peter, Wu, Stephen, Chung, Rossana, Zhang, Weiqun, Hulton, Chris, Ripley, Steven, Hirsch, Heather, Nagashima, Kumiko, Wong, Kwok-Kin, Jánne, Pasi A, Seidel-Dugan, Cynthia, Zawel, Leigh, Kirschmeier, Paul T, Middleton, Richard E, Morris, Erick J, Wang, Yan
Published in Molecular cancer research (01.07.2014)
Published in Molecular cancer research (01.07.2014)
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Journal Article
Development of a High-Throughput Gene Expression Screen for Modulators of RAS-MAPK Signaling in a Mutant RAS Cellular Context
Severyn, Bryan, Nguyen, Thi, Altman, Michael D., Li, Lixia, Nagashima, Kumiko, Naumov, George N., Sathyanarayanan, Sriram, Cook, Erica, Morris, Erick, Ferrer, Marc, Arthur, Bill, Benita, Yair, Watters, Jim, Loboda, Andrey, Hermes, Jeff, Gilliland, D. Gary, Cleary, Michelle A., Carroll, Pamela M., Strack, Peter, Tudor, Matt, Andersen, Jannik N.
Published in Journal of biomolecular screening (01.10.2016)
Published in Journal of biomolecular screening (01.10.2016)
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Journal Article
The Chk1/Cdc25A Pathway as Activators of the Cell Cycle in Neuronal Death Induced by Camptothecin
Zhang, Yi, Qu, Dianbo, Morris, Erick J, O'Hare, Michael J, Callaghan, Steven M, Slack, Ruth S, Geller, Herbert M, Park, David S
Published in The Journal of neuroscience (23.08.2006)
Published in The Journal of neuroscience (23.08.2006)
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Journal Article
Drosophila E2F1 Has Context-Specific Pro- and Antiapoptotic Properties during Development
Moon, Nam-Sung, Frolov, Maxim V., Kwon, Eun-Jeong, Di Stefano, Luisa, Dimova, Dessislava K., Morris, Erick J., Taylor-Harding, Barbie, White, Kristin, Dyson, Nicholas J.
Published in Developmental cell (01.10.2005)
Published in Developmental cell (01.10.2005)
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Journal Article
Multiple Pathways of Neuronal Death Induced by DNA-Damaging Agents, NGF Deprivation, and Oxidative Stress
Park, David S, Morris, Erick J, Stefanis, Leonidas, Troy, Carol M, Shelanski, Michael L, Geller, Herbert M, Greene, Lloyd A
Published in The Journal of neuroscience (01.02.1998)
Published in The Journal of neuroscience (01.02.1998)
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Journal Article
Drosophila homolog of human tumor suppressor TSC-22 promotes cellular growth, proliferation, and survival
Wu, Xiaodong, Yamada-Mabuchi, Megumu, Morris, Erick J, Tanwar, Pradeep Singh, Dobens, Leonard, Gluderer, Silvia, Khan, Sabina, Cao, Jing, Stocker, Hugo, Hafen, Ernst, Dyson, Nick J, Raftery, Laurel A
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2008)
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Journal Article
Oxidative stress mediates neuronal DNA damage and apoptosis in response to cytosine arabinoside
Geller, Herbert M., Cheng, Ke‐Yi, Goldsmith, Noriko K., Romero, Alejandro A., Zhang, Ai‐Ling, Morris, Erick J., Grandison, Lindsey
Published in Journal of neurochemistry (01.07.2001)
Published in Journal of neurochemistry (01.07.2001)
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Journal Article
Involvement of Retinoblastoma Family Members and E2F/DP Complexes in the Death of Neurons Evoked by DNA Damage
Park, David S, Morris, Erick J, Bremner, Rod, Keramaris, Elizabeth, Padmanabhan, Jaya, Rosenbaum, Michele, Shelanski, Michael L, Geller, Herbert M, Greene, Lloyd A
Published in The Journal of neuroscience (01.05.2000)
Published in The Journal of neuroscience (01.05.2000)
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Journal Article