Engineering of a light-gated potassium channel
Cosentino, Cristian, Alberio, Laura, Gazzarrini, Sabrina, Aquila, Marco, Romano, Edoardo, Cermenati, Solei, Zuccolini, Paolo, Petersen, Jan, Beltrame, Monica, Van Etten, James L., Christie, John M., Thiel, Gerhard, Moroni, Anna
Published in Science (American Association for the Advancement of Science) (08.05.2015)
Published in Science (American Association for the Advancement of Science) (08.05.2015)
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cyclic AMP Regulation and Its Command in the Pacemaker Channel HCN4
Porro, Alessandro, Thiel, Gerhard, Moroni, Anna, Saponaro, Andrea
Published in Frontiers in physiology (07.07.2020)
Published in Frontiers in physiology (07.07.2020)
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A high affinity switch for cAMP in the HCN pacemaker channels
Porro, Alessandro, Saponaro, Andrea, Castelli, Roberta, Introini, Bianca, Hafez Alkotob, Anahita, Ranjbari, Golnaz, Enke, Uta, Kusch, Jana, Benndorf, Klaus, Santoro, Bina, DiFrancesco, Dario, Thiel, Gerhard, Moroni, Anna
Published in Nature communications (29.01.2024)
Published in Nature communications (29.01.2024)
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The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels
Porro, Alessandro, Saponaro, Andrea, Gasparri, Federica, Bauer, Daniel, Gross, Christine, Pisoni, Matteo, Abbandonato, Gerardo, Hamacher, Kay, Santoro, Bina, Thiel, Gerhard, Moroni, Anna
Published in eLife (26.11.2019)
Published in eLife (26.11.2019)
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Tailoring baker's yeast Saccharomyces cerevisiae for functional testing of channelrhodopsin
Höler, Sebastian, Degreif, Daniel, Stix, Florentine, Yang, Shang, Gao, Shiqiang, Nagel, Georg, Moroni, Anna, Thiel, Gerhard, Bertl, Adam, Rauh, Oliver
Published in PloS one (13.04.2023)
Published in PloS one (13.04.2023)
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Structural basis for ion selectivity in TMEM175 K + channels
Brunner, Janine D, Jakob, Roman P, Schulze, Tobias, Neldner, Yvonne, Moroni, Anna, Thiel, Gerhard, Maier, Timm, Schenck, Stephan
Published in eLife (08.04.2020)
Published in eLife (08.04.2020)
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Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function
Saponaro, Andrea, Pauleta, Sofia R., Cantini, Francesca, Matzapetakis, Manolis, Hammann, Christian, Donadoni, Chiara, Hu, Lei, Thiel, Gerhard, Banci, Lucia, Santoro, Bina, Moroni, Anna
Published in Proceedings of the National Academy of Sciences - PNAS (07.10.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (07.10.2014)
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Journal Article
Tetramerization Dynamics of C-terminal Domain Underlies Isoform-specific cAMP Gating in Hyperpolarization-activated Cyclic Nucleotide-gated Channels
Lolicato, Marco, Nardini, Marco, Gazzarrini, Sabrina, Möller, Stefan, Bertinetti, Daniela, Herberg, Friedrich W., Bolognesi, Martino, Martin, Holger, Fasolini, Marina, Bertrand, Jay A., Arrigoni, Cristina, Thiel, Gerhard, Moroni, Anna
Published in The Journal of biological chemistry (30.12.2011)
Published in The Journal of biological chemistry (30.12.2011)
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Journal Article
Reconstitution and functional characterization of ion channels from nanodiscs in lipid bilayers
Winterstein, Laura-Marie, Kukovetz, Kerri, Rauh, Oliver, Turman, Daniel L, Braun, Christian, Moroni, Anna, Schroeder, Indra, Thiel, Gerhard
Published in The Journal of general physiology (02.04.2018)
Published in The Journal of general physiology (02.04.2018)
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Journal Article
A light-gated potassium channel for sustained neuronal inhibition
Alberio, Laura, Locarno, Andrea, Saponaro, Andrea, Romano, Edoardo, Bercier, Valérie, Albadri, Shahad, Simeoni, Federica, Moleri, Silvia, Pelucchi, Silvia, Porro, Alessandro, Marcello, Elena, Barsotti, Noemi, Kukovetz, Kerri, Boender, Arjen J., Contestabile, Andrea, Luo, Shizhen, Moutal, Aubin, Ji, Yingshi, Romani, Giulia, Beltrame, Monica, Del Bene, Filippo, Di Luca, Monica, Khanna, Rajesh, Colecraft, Henry M., Pasqualetti, Massimo, Thiel, Gerhard, Tonini, Raffaella, Moroni, Anna
Published in Nature methods (01.11.2018)
Published in Nature methods (01.11.2018)
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Mechanism of the Pseudoirreversible Binding of Amantadine to the M2 Proton Channel
Llabrés, Salomé, Juárez-Jiménez, Jordi, Masetti, Matteo, Leiva, Rosana, Vázquez, Santiago, Gazzarrini, Sabrina, Moroni, Anna, Cavalli, Andrea, Luque, F. Javier
Published in Journal of the American Chemical Society (30.11.2016)
Published in Journal of the American Chemical Society (30.11.2016)
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Journal Article
A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels
Saponaro, Andrea, Cantini, Francesca, Porro, Alessandro, Bucchi, Annalisa, DiFrancesco, Dario, Maione, Vincenzo, Donadoni, Chiara, Introini, Bianca, Mesirca, Pietro, Mangoni, Matteo E, Thiel, Gerhard, Banci, Lucia, Santoro, Bina, Moroni, Anna
Published in eLife (20.06.2018)
Published in eLife (20.06.2018)
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Seizures, behavioral deficits, and adverse drug responses in two new genetic mouse models of HCN1 epileptic encephalopathy
Merseburg, Andrea, Kasemir, Jacquelin, Buss, Eric W, Leroy, Felix, Bock, Tobias, Porro, Alessandro, Barnett, Anastasia, Tröder, Simon E, Engeland, Birgit, Stockebrand, Malte, Moroni, Anna, Siegelbaum, Steven A, Isbrandt, Dirk, Santoro, Bina
Published in eLife (16.08.2022)
Published in eLife (16.08.2022)
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Journal Article
Characterization of an N-terminal Nav1.5 channel variant – a potential risk factor for arrhythmias and sudden death?
Scheiper-Welling, Stefanie, Zuccolini, Paolo, Rauh, Oliver, Beckmann, Britt-Maria, Geisen, Christof, Moroni, Anna, Thiel, Gerhard, Kauferstein, Silke
Published in BMC medical genetics (19.11.2020)
Published in BMC medical genetics (19.11.2020)
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Journal Article
Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness
Lolicato, Marco, Bucchi, Annalisa, Arrigoni, Cristina, Zucca, Stefano, Nardini, Marco, Schroeder, Indra, Simmons, Katie, Aquila, Marco, DiFrancesco, Dario, Bolognesi, Martino, Schwede, Frank, Kashin, Dmitry, Fishwick, Colin W G, Johnson, A Peter, Thiel, Gerhard, Moroni, Anna
Published in Nature chemical biology (01.06.2014)
Published in Nature chemical biology (01.06.2014)
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Journal Article
Ionizing Radiation Induces Morphological Changes and Immunological Modulation of Jurkat Cells
Voos, Patrick, Fuck, Sebastian, Weipert, Fabian, Babel, Laura, Tandl, Dominique, Meckel, Tobias, Hehlgans, Stephanie, Fournier, Claudia, Moroni, Anna, Rödel, Franz, Thiel, Gerhard
Published in Frontiers in immunology (30.04.2018)
Published in Frontiers in immunology (30.04.2018)
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Journal Article
Effect of cytosolic pH on inward currents reveals structural characteristics of the proton transport cycle in the influenza A protein M2 in cell-free membrane patches of Xenopus oocytes
DiFrancesco, Mattia L, Hansen, Ulf-Peter, Thiel, Gerhard, Moroni, Anna, Schroeder, Indra
Published in PloS one (11.09.2014)
Published in PloS one (11.09.2014)
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Journal Article
A Functional K + Channel from Tetraselmis Virus 1, a Member of the Mimiviridae
Kukovetz, Kerri, Hertel, Brigitte, Schvarcz, Christopher R, Saponaro, Andrea, Manthey, Mirja, Burk, Ulrike, Greiner, Timo, Steward, Grieg F, Van Etten, James L, Moroni, Anna, Thiel, Gerhard, Rauh, Oliver
Published in Viruses (29.09.2020)
Published in Viruses (29.09.2020)
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