4-Amido-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-ones as New Potent and Selective Human A3 Adenosine Receptor Antagonists. Synthesis, Pharmacological Evaluation, and Ligand−Receptor Modeling Studies
Lenzi, Ombretta, Colotta, Vittoria, Catarzi, Daniela, Varano, Flavia, Filacchioni, Guido, Martini, Claudia, Trincavelli, Letizia, Ciampi, Osele, Varani, Katia, Marighetti, Federico, Morizzo, Erika, Moro, Stefano
Published in Journal of medicinal chemistry (29.06.2006)
Published in Journal of medicinal chemistry (29.06.2006)
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LBP-031 AZD2693, a potent PNPLA3 antisense oligonucleotide, decreases hepatic PNPLA3 mRNA and liver fat content in participants with presumed MASH and homozygous for the PNPLA3148M risk allele
Armisen, Javier, Rauschecker, Mitra, Sarv, Janeli, Liljeblad, Mathias, Niazi, Mohammad, Clewe, Oskar, Eklund, Olof, Sandell, Therese, Linden, Daniel, Hallen, Stefan, Wernevik, Linda, Köster, Sofia, Morizzo, Erika, Sundelin, Jeanna, Carlsson, Björn, Hansen, Lars, Knöchel, Jane, Bhanot, Sanjay, Guo, Shuling, Fjellstrom, Ola, Blau, Jenny, Loomba, Rohit
Published in Journal of hepatology (01.06.2024)
Published in Journal of hepatology (01.06.2024)
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IMPROVED SERUM ALBUMIN BINDING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS
PONSAERTS RAF, STEFFENSEN SOREN, CERDOBBEL AN, OTTEVAERE INGRID, STAELENS STEPHANIE, MORIZZO ERIKA
Year of Publication 03.01.2024
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Year of Publication 03.01.2024
Patent
High Throughput Combinatorial Formatting of PcrV Nanobodies for Efficient Potency Improvement
De Tavernier, Evelyn, Detalle, Laurent, Morizzo, Erika, Roobrouck, Annelies, De Taeye, Severine, Rieger, Melanie, Verhaeghe, Tom, Correia, Andreia, Van Hegelsom, Rob, Figueirido, Rita, Noens, Jeroen, Steffensen, Søren, Stöhr, Thomas, Van de Velde, Willem, Depla, Erik, Dombrecht, Bruno
Published in The Journal of biological chemistry (15.07.2016)
Published in The Journal of biological chemistry (15.07.2016)
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Journal Article
IMPROVED SERUM ALBUMIN BINDING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS
PONSAERTS RAF, STEFFENSEN SOREN, CERDOBBEL AN, OTTEVAERE INGRID, STAELENS STEPHANIE, MORIZZO ERIKA
Year of Publication 08.05.2023
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Year of Publication 08.05.2023
Patent
2-Phenylpyrazolo[4,3-d]pyrimidin-7-one as a New Scaffold To Obtain Potent and Selective Human A(3) Adenosine Receptor Antagonists: New Insights into the Receptor-Antagonist Recognition
Lenzi, Ombretta, Colotta, Vittoria, Catarzi, Daniela, Varano, Flavia, Poli, Daniela, Filacchioni, Guido, Varani, Katia, Vincenzi, Fabrizio, Borea, Pier Andrea, Paoletta, Silvia, Morizzo, Erika, Moro, Stefano
Published in Journal of medicinal chemistry (10.12.2009)
Published in Journal of medicinal chemistry (10.12.2009)
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Journal Article
2-Phenylpyrazolo[4,3-d]pyrimidin-7-one as a New Scaffold To Obtain Potent and Selective Human A3 Adenosine Receptor Antagonists: New Insights into the Receptor−Antagonist Recognition
Lenzi, Ombretta, Colotta, Vittoria, Catarzi, Daniela, Varano, Flavia, Poli, Daniela, Filacchioni, Guido, Varani, Katia, Vincenzi, Fabrizio, Borea, Pier Andrea, Paoletta, Silvia, Morizzo, Erika, Moro, Stefano
Published in Journal of medicinal chemistry (10.12.2009)
Published in Journal of medicinal chemistry (10.12.2009)
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Pyrido[2,3-e]-1,2,4-triazolo[4,3-a]pyrazin-1-one as a New Scaffold To Develop Potent and Selective Human A3 Adenosine Receptor Antagonists. Synthesis, Pharmacological Evaluation, and Ligand−Receptor Modeling Studies
Colotta, Vittoria, Lenzi, Ombretta, Catarzi, Daniela, Varano, Flavia, Filacchioni, Guido, Martini, Claudia, Trincavelli, Letizia, Ciampi, Osele, Pugliese, Anna Maria, Traini, Chiara, Pedata, Felicita, Morizzo, Erika, Moro, Stefano
Published in Journal of medicinal chemistry (23.04.2009)
Published in Journal of medicinal chemistry (23.04.2009)
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Journal Article
Pyrido[2,3-e]-1,2,4-triazolo[4,3-a]pyrazin-1-one as a New Scaffold To Develop Potent and Selective Human A(3) Adenosine Receptor Antagonists. Synthesis, Pharmacological Evaluation, and Ligand-Receptor Modeling Studies
Colotta, Vittoria, Lenzi, Ombretta, Catarzi, Daniela, Varano, Flavia, Filacchioni, Guido, Martini, Claudia, Trincavelli, Letizia, Ciampi, Osele, Pugliese, Anna Maria, Traini, Chiara, Pedata, Felicita, Morizzo, Erika, Moro, Stefano
Published in Journal of medicinal chemistry (23.04.2009)
Published in Journal of medicinal chemistry (23.04.2009)
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New 2-Arylpyrazolo[3,4-c]quinoline Derivatives as Potent and Selective Human A3 Adenosine Receptor Antagonists. Synthesis, Pharmacological Evaluation, and Ligand−Receptor Modeling Studies
Colotta, Vittoria, Catarzi, Daniela, Varano, Flavia, Capelli, Francesca, Lenzi, Ombretta, Filacchioni, Guido, Martini, Claudia, Trincavelli, Letizia, Ciampi, Osele, Pugliese, Anna Maria, Pedata, Felicita, Schiesaro, Andrea, Morizzo, Erika, Moro, Stefano
Published in Journal of medicinal chemistry (23.08.2007)
Published in Journal of medicinal chemistry (23.08.2007)
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Journal Article
New 2-arylpyrazolo[3,4-c]quinoline derivatives as potent and selective human A(3) adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies
Colotta, Vittoria, Catarzi, Daniela, Varano, Flavia, Capelli, Francesca, Lenzi, Ombretta, Filacchioni, Guido, Martini, Claudia, Trincavelli, Letizia, Ciampi, Osele, Pugliese, Anna Maria, Pedata, Felicita, Schiesaro, Andrea, Morizzo, Erika, Moro, Stefano
Published in Journal of medicinal chemistry (23.08.2007)
Published in Journal of medicinal chemistry (23.08.2007)
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개선된 혈청 알부민 결합성 면역글로불린 단일 가변 도메인
PONSAERTS RAF, STEFFENSEN SOREN, CERDOBBEL AN, OTTEVAERE INGRID, STAELENS STEPHANIE, MORIZZO ERIKA
Year of Publication 06.08.2019
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Year of Publication 06.08.2019
Patent
4-amido-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-ones as new potent and selective human A(3) adenosine receptor antagonists. synthesis, pharmacological evaluation, and ligand-receptor modeling studies
Lenzi, Ombretta, Colotta, Vittoria, Catarzi, Daniela, Varano, Flavia, Filacchioni, Guido, Martini, Claudia, Trincavelli, Letizia, Ciampi, Osele, Varani, Katia, Marighetti, Federico, Morizzo, Erika, Moro, Stefano
Published in Journal of medicinal chemistry (29.06.2006)
Published in Journal of medicinal chemistry (29.06.2006)
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Journal Article
Synthesis, ligand-receptor modeling studies and pharmacological evaluation of novel 4-modified-2-aryl-1,2,4-triazolo[4,3-a] quinoxalin-1-one derivatives as potent and selective human A3 adenosine receptor antagonists
COLOTTA, Vittoria, CATARZI, Daniela, PEDATA, Felicita, MORIZZO, Erika, MORO, Stefano, VARANO, Flavia, LENZI, Ombretta, FILACCHIONI, Guido, MARTINI, Claudia, TRINCAVELLI, Letizia, CIAMPI, Osele, TRAINI, Chiara, PUGLIESE, Anna Maria
Published in Bioorganic & medicinal chemistry (01.06.2008)
Published in Bioorganic & medicinal chemistry (01.06.2008)
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Journal Article
Scouting human A(3) adenosine receptor antagonist binding mode using a molecular simplification approach: From triazoloquinoxaline to a pyrimidine skeleton as a key study
Morizzo, Erika, Capelli, Francesca, Lenzi, Ombretta, Catarzi, Daniela, Varano, Flavia, Filacchioni, Guido, Vincenzi, Fabrizio, Varani, Katia, Borea, Pier Andrea, Colotta, Vittoria, Moro, Stefano
Published in Journal of medicinal chemistry (27.12.2007)
Published in Journal of medicinal chemistry (27.12.2007)
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