Search Results - "MORITOMO, HIROYUKI" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Synthesis and evaluation of novel phenoxypropanolamine derivatives containing acetanilides as potent and selective β3-adrenergic receptor agonists

Synthesis and evaluation of novel phenoxypropanolamine derivatives containing acetanilides as potent and selective β3-adrenergic receptor agonists

by Maruyama, Tatsuya, Onda, Kenichi, Hayakawa, Masahiko, Seki, Norio, Takahashi, Takumi, Moritomo, Hiroyuki, Suzuki, Takayuki, Matsui, Tetsuo, Takasu, Toshiyuki, Nagase, Itsuro, Ohta, Mitsuaki
Published in Bioorganic & medicinal chemistry (01.05.2009)

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Journal Article

Discovery of ASP5878: Synthesis and structure–activity relationships of pyrimidine derivatives as pan-FGFRs inhibitors with improved metabolic stability and suppressed hERG channel inhibitory activity

Discovery of ASP5878: Synthesis and structure–activity relationships of pyrimidine derivatives as pan-FGFRs inhibitors with improved metabolic stability and suppressed hERG channel inhibitory activity

by Kuriwaki, Ikumi, Kameda, Minoru, Iikubo, Kazuhiko, Hisamichi, Hiroyuki, Kawamoto, Yuichiro, Kikuchi, Shigetoshi, Moritomo, Hiroyuki, Terasaka, Tadashi, Iwai, Yoshinori, Noda, Atsushi, Tomiyama, Hiroshi, Kikuchi, Aya, Hirano, Masaaki
Published in Bioorganic & medicinal chemistry (01.04.2022)

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Journal Article

Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2

Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2

by Kuriwaki, Ikumi, Kameda, Minoru, Hisamichi, Hiroyuki, Kikuchi, Shigetoshi, Iikubo, Kazuhiko, Kawamoto, Yuichiro, Moritomo, Hiroyuki, Kondoh, Yutaka, Amano, Yasushi, Tateishi, Yukihiro, Echizen, Yuka, Iwai, Yoshinori, Noda, Atsushi, Tomiyama, Hiroshi, Suzuki, Tomoyuki, Hirano, Masaaki
Published in Bioorganic & medicinal chemistry (15.05.2020)

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Synthesis and structure-activity relationships of pyrimidine derivatives as potent and orally active FGFR3 inhibitors with both increased systemic exposure and enhanced in vitro potency

Synthesis and structure-activity relationships of pyrimidine derivatives as potent and orally active FGFR3 inhibitors with both increased systemic exposure and enhanced in vitro potency

by Kuriwaki, Ikumi, Kameda, Minoru, Iikubo, Kazuhiko, Hisamichi, Hiroyuki, Kawamoto, Yuichiro, Kikuchi, Shigetoshi, Moritomo, Hiroyuki, Kondoh, Yutaka, Terasaka, Tadashi, Amano, Yasushi, Tateishi, Yukihiro, Echizen, Yuka, Iwai, Yoshinori, Noda, Atsushi, Tomiyama, Hiroshi, Nakazawa, Taisuke, Hirano, Masaaki
Published in Bioorganic & medicinal chemistry (01.03.2021)

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Synthesis and biological evaluation of 4-morpholino-2-phenylquinazolines and related derivatives as novel PI3 kinase p110α inhibitors

Synthesis and biological evaluation of 4-morpholino-2-phenylquinazolines and related derivatives as novel PI3 kinase p110α inhibitors

by Hayakawa, Masahiko, Kaizawa, Hiroyuki, Moritomo, Hiroyuki, Koizumi, Tomonobu, Ohishi, Takahide, Okada, Minoru, Ohta, Mitsuaki, Tsukamoto, Shin-ichi, Parker, Peter, Workman, Paul, Waterfield, Mike
Published in Bioorganic & medicinal chemistry (15.10.2006)

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Journal Article

Construction of three types of fused isoindoles via furan-pyrrole ring exchange reaction

Construction of three types of fused isoindoles via furan-pyrrole ring exchange reaction

by Lee, Mase, Moritomo, Hiroyuki, Kanematsu, Ken
Published in Tetrahedron (10.06.1996)

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Journal Article

Synthesis and biological evaluation of pyrido[3′,2′:4,5]furo[3,2- d]pyrimidine derivatives as novel PI3 kinase p110α inhibitors

Synthesis and biological evaluation of pyrido[3′,2′:4,5]furo[3,2- d]pyrimidine derivatives as novel PI3 kinase p110α inhibitors

by Hayakawa, Masahiko, Kaizawa, Hiroyuki, Moritomo, Hiroyuki, Koizumi, Tomonobu, Ohishi, Takahide, Yamano, Mayumi, Okada, Minoru, Ohta, Mitsuaki, Tsukamoto, Shin-ichi, Raynaud, Florence I., Workman, Paul, Waterfield, Michael D., Parker, Peter
Published in Bioorganic & medicinal chemistry letters (01.05.2007)

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Journal Article

PIPERAZINE DERIVATIVE

PIPERAZINE DERIVATIVE

by MORITOMO, Hiroyuki, SUGANE, Takashi, YAMASHITA, Daisuke, HOSOGAI, Naomi, ASAI, Norio
Year of Publication 25.01.2018

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Patent

HETEROCYCLIC ACETIC ACID AMIDE COMPOUND

HETEROCYCLIC ACETIC ACID AMIDE COMPOUND

by MORITOMO HIROYUKI, OHMIYA MAKOTO, TOBE TAKAHIKO, SHIRAKI RYOTA, KAWAKAMI SHIMPEI
Year of Publication 23.12.2015

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Patent

HETEROCYCLIC ACETIC ACID AMIDE COMPOUND

HETEROCYCLIC ACETIC ACID AMIDE COMPOUND

by TOBE, TAKAHIKO, OHMIYA, MAKOTO, KAWAKAMI, SHIMPEI, MORITOMO, HIROYUKI, SHIRAKI, RYOTA
Year of Publication 23.10.2014

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Patent

피페라진 유도체

피페라진 유도체

by HOSOGAI NAOMI, TANABE DAISUKE, MIHARA HISASHI, MORITOMO HIROYUKI, YAMASHITA DAISUKE, YONETOKU YASUHIRO, OSODA KAZUHIKO, ASAI NORIO, SUGANE TAKASHI, MAENO KYOICHI, SUGASAWA KEIZO, SHIMIZU TAKAFUMI, MAKINO TAKUYA
Year of Publication 30.03.2018

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Patent

Synthesis and evaluation of novel phenoxypropanolamine derivatives containing acetanilides as potent and selective beta 3-adrenergic receptor agonists

Synthesis and evaluation of novel phenoxypropanolamine derivatives containing acetanilides as potent and selective beta 3-adrenergic receptor agonists

by Maruyama, Tatsuya, Onda, Kenichi, Hayakawa, Masahiko, Seki, Norio, Takahashi, Takumi, Moritomo, Hiroyuki, Suzuki, Takayuki, Matsui, Tetsuo, Takasu, Toshiyuki, Nagase, Itsuro, Ohta, Mitsuaki
Published in Bioorganic & medicinal chemistry (01.05.2009)

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Journal Article

PIPERAZINE DERIVATIVE

PIPERAZINE DERIVATIVE

by SUGASAWA, Keizo, MAENO, Kyoichi, MIHARA, Hisashi, MAKINO, Takuya, OSODA, Kazuhiko, MORITOMO, Hiroyuki, HOSOGAI, Naomi, ASAI, Norio, YONETOKU, Yasuhiro, SHIMIZU, Takafumi, SUGANE, Takashi, YAMASHITA, Daisuke, TANABE, Daisuke
Year of Publication 09.02.2017

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Patent

Identification of 4-benzylamino-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5-carboxamide derivatives as potent and orally bioavailable STAT6 inhibitors

Identification of 4-benzylamino-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5-carboxamide derivatives as potent and orally bioavailable STAT6 inhibitors

by Nagashima, Shinya, Nagata, Hiroshi, Iwata, Masahiro, Yokota, Masaki, Moritomo, Hiroyuki, Orita, Masaya, Kuromitsu, Sadao, Koakutsu, Akiko, Ohga, Keiko, Takeuchi, Makoto, Ohta, Mitsuaki, Tsukamoto, Shin-ichi
Published in Bioorganic & medicinal chemistry (01.07.2008)

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Journal Article

Condensed heteroaryl derivatives

Condensed heteroaryl derivatives

by HAYAKAWA MASAHIKO,KAIZAWA HIROYUKI,MORITOMO HIROYUKI,KAWAGUCHI KEN-ICHI,KOIZUMI TOMONOBU,YAMANO MAYUMI,MATSUDA KOYO,OKADA MINORU,OHTA MITSUAKI
Year of Publication 31.10.2007

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Patent

BICYCLIC HETEROCYCLIC COMPOUND

BICYCLIC HETEROCYCLIC COMPOUND

by SEKIOKA RYUICHI, SUZUKI TAKAYUKI, HAMAGUCHI WATARU, MORITOMO AYAKO, MORITOMO HIROYUKI, KAWANO NORIYUKI, SAKURAI MINORU, SHIRAISHI NOBUYUKI, KAWAKAMI SHIMPEI
Year of Publication 01.07.2014

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Patent

Synthesis and evaluation of novel phenoxypropanolamine derivatives containing acetanilides as potent and selective p3-adrenergic receptor agonists

Synthesis and evaluation of novel phenoxypropanolamine derivatives containing acetanilides as potent and selective p3-adrenergic receptor agonists

by MARUYAMA, Tatsuya, ONDA, Kenichi, OHTA, Mitsuaki, HAYAKAWA, Masahiko, SEKI, Norio, TAKAHASHI, Takumi, MORITOMO, Hiroyuki, SUZUKI, Takayuki, MATSUI, Tetsuo, TAKASU, Toshiyuki, NAGASE, Itsuro
Published in Bioorganic & medicinal chemistry (2009)

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Journal Article

TETRAHYDROBENZOTHIOPHENE COMPOUND

TETRAHYDROBENZOTHIOPHENE COMPOUND

by IMAMURA YOSHIMASA, SATO IPPEI, TERAI KAZUHIRO, MORITOMO HIROYUKI, HACHIYA SHUNICHIRO, TERADA YOH, KATO KOJI, MIURA MASANORI, KAGA DAISUKE
Year of Publication 03.07.2013

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Patent

BICYCLIC HETEROCYCLIC COMPOUND

BICYCLIC HETEROCYCLIC COMPOUND

by SAKURAI, MINORU, SEKIOKA, RYUICHI, KAWANO, NORIYUKI, SUZUKI, TAKAYUKI, HAMAGUCHI, WATARU, MORITOMO, AYAKO, KAWAKAMI, SHIMPEI, SHIRAISHI, NOBUYUKI, MORITOMO, HIROYUKI
Year of Publication 25.04.2013

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Patent

BICYCLIC HETEROCYCLIC COMPOUND

BICYCLIC HETEROCYCLIC COMPOUND

by KAMIKUBO, TAKASHI, KOGA, YUJI, OKUDA, TAKAO, MORITOMO, HIROYUKI, KAGEYAMA, MICHIHITO
Year of Publication 06.11.2008

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Patent

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