Search Results - "MORIMOTO, AKIFUMI" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery of Novel Indazole Derivatives as Orally Available β3‑Adrenergic Receptor Agonists Lacking Off-Target-Based Cardiovascular Side Effects

Discovery of Novel Indazole Derivatives as Orally Available β3‑Adrenergic Receptor Agonists Lacking Off-Target-Based Cardiovascular Side Effects

by Wada, Yasuhiro, Nakano, Seiji, Morimoto, Akifumi, Kasahara, Ken-ichi, Hayashi, Takahiko, Takada, Yoshio, Suzuki, Hiroko, Niwa-Sakai, Michiko, Ohashi, Shigeki, Mori, Mutsuhiro, Hirokawa, Takatsugu, Shuto, Satoshi
Published in Journal of medicinal chemistry (27.04.2017)

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Journal Article

Discovery of Novel Indazole Derivatives as Orally Available beta(3)-Adrenergic Receptor Agonists Lacking Off-Target-Based Cardiovascular Side Effects

Discovery of Novel Indazole Derivatives as Orally Available beta(3)-Adrenergic Receptor Agonists Lacking Off-Target-Based Cardiovascular Side Effects

by Wada, Yasuhiro, Nakano, Seiji, Morimoto, Akifumi, Kasahara, Ken-ichi, Hayashi, Takahiko, Takada, Yoshio, Suzuki, Hiroko, Niwa-Sakai, Michiko, Ohashi, Shigeki, Mori, Mutsuhiro, Hirokawa, Takatsugu, Shuto, Satoshi
Published in Journal of medicinal chemistry (27.04.2017)

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Journal Article

Discovery of Novel Indazole Derivatives as Highly Potent and Selective Human β3‑Adrenergic Receptor Agonists with the Possibility of Having No Cardiovascular Side Effects

Discovery of Novel Indazole Derivatives as Highly Potent and Selective Human β3‑Adrenergic Receptor Agonists with the Possibility of Having No Cardiovascular Side Effects

by Wada, Yasuhiro, Shirahashi, Hiromitsu, Iwanami, Taisuke, Ogawa, Masami, Nakano, Seiji, Morimoto, Akifumi, Kasahara, Ken-ichi, Tanaka, Eiichi, Takada, Yoshio, Ohashi, Shigeki, Mori, Mutsuhiro, Shuto, Satoshi
Published in Journal of medicinal chemistry (13.08.2015)

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Journal Article

Discovery of 2-(1H-indazol-1-yl)-thiazole derivatives as selective EP1 receptor antagonists for treatment of overactive bladder by core structure replacement

Discovery of 2-(1H-indazol-1-yl)-thiazole derivatives as selective EP1 receptor antagonists for treatment of overactive bladder by core structure replacement

by Atobe, Masakazu, Naganuma, Kenji, Kawanishi, Masashi, Morimoto, Akifumi, Kasahara, Ken-ichi, Ohashi, Shigeki, Suzuki, Hiroko, Hayashi, Takahiko, Miyoshi, Shiro
Published in Bioorganic & medicinal chemistry letters (01.03.2014)

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Journal Article

Discovery of Novel Indazole Derivatives as Orally Available β 3 -Adrenergic Receptor Agonists Lacking Off-Target-Based Cardiovascular Side Effects

Discovery of Novel Indazole Derivatives as Orally Available β 3 -Adrenergic Receptor Agonists Lacking Off-Target-Based Cardiovascular Side Effects

by Wada, Yasuhiro, Nakano, Seiji, Morimoto, Akifumi, Kasahara, Ken-Ichi, Hayashi, Takahiko, Takada, Yoshio, Suzuki, Hiroko, Niwa-Sakai, Michiko, Ohashi, Shigeki, Mori, Mutsuhiro, Hirokawa, Takatsugu, Shuto, Satoshi
Published in Journal of medicinal chemistry (27.04.2017)

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Journal Article

SAR-based optimization of 2-(1H-pyrazol-1-yl)-thiazole derivatives as highly potent EP1 receptor antagonists

SAR-based optimization of 2-(1H-pyrazol-1-yl)-thiazole derivatives as highly potent EP1 receptor antagonists

by Atobe, Masakazu, Naganuma, Kenji, Kawanishi, Masashi, Morimoto, Akifumi, Kasahara, Ken-ichi, Ohashi, Shigeki, Suzuki, Hiroko, Hayashi, Takahiko, Miyoshi, Shiro
Published in Bioorganic & medicinal chemistry letters (15.12.2013)

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Journal Article

Hit-to-lead optimization of 2-(1H-pyrazol-1-yl)-thiazole derivatives as a novel class of EP1 receptor antagonists

Hit-to-lead optimization of 2-(1H-pyrazol-1-yl)-thiazole derivatives as a novel class of EP1 receptor antagonists

by Atobe, Masakazu, Naganuma, Kenji, Kawanishi, Masashi, Morimoto, Akifumi, Kasahara, Ken-ichi, Ohashi, Shigeki, Suzuki, Hiroko, Hayashi, Takahiko, Miyoshi, Shiro
Published in Bioorganic & medicinal chemistry letters (15.11.2013)

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Journal Article

Discovery of Novel Indazole Derivatives as Highly Potent and Selective Human β 3 -Adrenergic Receptor Agonists with the Possibility of Having No Cardiovascular Side Effects

Discovery of Novel Indazole Derivatives as Highly Potent and Selective Human β 3 -Adrenergic Receptor Agonists with the Possibility of Having No Cardiovascular Side Effects

by Wada, Yasuhiro, Shirahashi, Hiromitsu, Iwanami, Taisuke, Ogawa, Masami, Nakano, Seiji, Morimoto, Akifumi, Kasahara, Ken-ichi, Tanaka, Eiichi, Takada, Yoshio, Ohashi, Shigeki, Mori, Mutsuhiro, Shuto, Satoshi
Published in Journal of medicinal chemistry (13.08.2015)

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Journal Article

INDAZOLE ANALOGUE

INDAZOLE ANALOGUE

by WADA YASUHIRO, MORIMOTO AKIFUMI
Year of Publication 07.04.2011

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Patent

INDAZOLE DERIVATIVE

INDAZOLE DERIVATIVE

by NAKANO SEIJI, WADA YASUHIRO, MORIMOTO AKIFUMI
Year of Publication 16.05.2011

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Patent

BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS

BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS

by ATOBE MASAKAZU, NAGANUMA KENJI, MORIMOTO AKIFUMI
Year of Publication 22.11.2010

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Patent

INDAZOLE DERIVATIVE

INDAZOLE DERIVATIVE

by NAKANO SEIJI, WADA YASUHIRO, MORIMOTO AKIFUMI
Year of Publication 15.04.2010

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Patent

NITROGENATED BICYCLIC HETEROCYCLIC COMPOUND

NITROGENATED BICYCLIC HETEROCYCLIC COMPOUND

by ATOBE MASAKAZU, NAGANUMA KENJI, MORIMOTO AKIFUMI
Year of Publication 21.01.2010

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Patent

Discovery of 2-(1H-indazol-1-yl)-thiazole derivatives as selective EP(1) receptor antagonists for treatment of overactive bladder by core structure replacement

Discovery of 2-(1H-indazol-1-yl)-thiazole derivatives as selective EP(1) receptor antagonists for treatment of overactive bladder by core structure replacement

by Atobe, Masakazu, Naganuma, Kenji, Kawanishi, Masashi, Morimoto, Akifumi, Kasahara, Ken-ichi, Ohashi, Shigeki, Suzuki, Hiroko, Hayashi, Takahiko, Miyoshi, Shiro
Published in Bioorganic & medicinal chemistry letters (01.03.2014)

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Journal Article

INDAZOLE COMPOUND

INDAZOLE COMPOUND

by IWANAMI TAISUKE, NAKANO SEIJI, WADA YASUHIRO, YAMANISHI KEI, MORIMOTO AKIFUMI
Year of Publication 16.05.2011

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Patent

NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS

NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS

by ATOBE MASAKAZU, KOBAYASHI TERUKI, NAGANUMA KENJI, MORIMOTO AKIFUMI
Year of Publication 22.11.2010

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Patent

INDAZOLE COMPOUND

INDAZOLE COMPOUND

by IWANAMI TAISUKE, NAKANO SEIJI, WADA YASUHIRO, YAMANISHI KEI, MORIMOTO AKIFUMI
Year of Publication 15.04.2010

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Patent

NITROGENATED HETEROCYCLIC COMPOUND

NITROGENATED HETEROCYCLIC COMPOUND

by ATOBE MASAKAZU, KOBAYASHI TERUKI, NAGANUMA KENJI, MORIMOTO AKIFUMI
Year of Publication 21.01.2010

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Patent

Construction of Engineered Water-soluble PQQ Glucose Dehydrogenase with Improved Substrate Specificity

Construction of Engineered Water-soluble PQQ Glucose Dehydrogenase with Improved Substrate Specificity

by Sode, Koji, Igarashi, Satoshi, Morimoto, Akifumi, Yoshida, Hiromi
Published in Biocatalysis and biotransformation (01.01.2002)

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Journal Article

INDAZOLE ANALOGUE

INDAZOLE ANALOGUE

by WADA YASUHIRO, MORIMOTO AKIFUMI
Year of Publication 27.03.2013

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Patent