DEVELOPMENT OF AN IN VIVO PRECLINICAL SCREEN MODEL TO ESTIMATE ABSORPTION AND FIRST-PASS HEPATIC EXTRACTION OF XENOBIOTICS. II. USE OF KETOCONAZOLE TO IDENTIFY P-GLYCOPROTEIN/CYP3A-LIMITED BIOAVAILABILITY IN THE MONKEY
WARD, Keith W, STELMAN, Gary J, MORGAN, Jayme A, ZEIGLER, Kelli S, AZZARANO, Leonard M, KEHLER, Jonathan R, MCSURDY-FREED, Jeanelle E, PROKSCH, Joel W, SMITH, Brian R
Published in Drug metabolism and disposition (01.02.2004)
Published in Drug metabolism and disposition (01.02.2004)
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Pharmacokinetics of SB-247083, a potent and selective endothelinA receptor antagonist, in the rat, dog, and monkey
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Published in Biopharmaceutics & drug disposition (01.11.2002)
Published in Biopharmaceutics & drug disposition (01.11.2002)
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Journal Article
Pharmacokinetics of SB-247083, a potent and selective endothelin(A) receptor antagonist, in the rat, dog, and monkey
Ward, Keith W, Azzarano, Leonard M, Morgan, Jayme A, Gould, Michael J, Perng, Cherng-Yih, Souder, Pamela R, Lundberg, David, Smith, Brian R
Published in Biopharmaceutics & drug disposition (01.11.2002)
Published in Biopharmaceutics & drug disposition (01.11.2002)
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Journal Article