Discovery of a Cyclic Boronic Acid β‑Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases
Hecker, Scott J, Reddy, K. Raja, Totrov, Maxim, Hirst, Gavin C, Lomovskaya, Olga, Griffith, David C, King, Paula, Tsivkovski, Ruslan, Sun, Dongxu, Sabet, Mojgan, Tarazi, Ziad, Clifton, Matthew C, Atkins, Kateri, Raymond, Amy, Potts, Kristy T, Abendroth, Jan, Boyer, Serge H, Loutit, Jeffrey S, Morgan, Elizabeth E, Durso, Stephanie, Dudley, Michael N
Published in Journal of medicinal chemistry (14.05.2015)
Published in Journal of medicinal chemistry (14.05.2015)
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Journal Article
Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of the β-Lactamase Inhibitor Vaborbactam (RPX7009) in Healthy Adult Subjects
Griffith, David C, Loutit, Jeffery S, Morgan, Elizabeth E, Durso, Stephanie, Dudley, Michael N
Published in Antimicrobial agents and chemotherapy (01.10.2016)
Published in Antimicrobial agents and chemotherapy (01.10.2016)
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Journal Article
Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of Vaborbactam and Meropenem Alone and in Combination following Single and Multiple Doses in Healthy Adult Subjects
Rubino, Christopher M, Bhavnani, Sujata M, Loutit, Jeffery S, Morgan, Elizabeth E, White, Dan, Dudley, Michael N, Griffith, David C
Published in Antimicrobial agents and chemotherapy (01.04.2018)
Published in Antimicrobial agents and chemotherapy (01.04.2018)
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Journal Article
A phase I, randomized, double-blind, placebo-controlled, ascending single- and multiple-dose study of the pharmacokinetics, safety, and tolerability of oral ceftibuten in healthy adult subjects
Hernández-Mitre, María Patricia, Wallis, Steven C, Morgan, Elizabeth E, Dudley, Michael N, Loutit, Jeffery S, Griffith, David C, Roberts, Jason A
Published in Antimicrobial agents and chemotherapy (10.01.2024)
Published in Antimicrobial agents and chemotherapy (10.01.2024)
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A phase 3, multi-center, multinational, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of levofloxacin inhalation solution (APT-1026) in stable cystic fibrosis patients
Flume, Patrick A, VanDevanter, Donald R, Morgan, Elizabeth E, Dudley, Michael N, Loutit, Jeffery S, Bell, Scott C, Kerem, Eitan, Fischer, Rainald, Smyth, Alan R, Aaron, Shawn D, Conrad, Douglas, Geller, David E, Elborn, J. Stuart
Published in Journal of cystic fibrosis (01.07.2016)
Published in Journal of cystic fibrosis (01.07.2016)
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Journal Article
A phase 3, open-label, randomized trial to evaluate the safety and efficacy of levofloxacin inhalation solution (APT-1026) versus tobramycin inhalation solution in stable cystic fibrosis patients
Stuart Elborn, J, Geller, David E, Conrad, Douglas, Aaron, Shawn D, Smyth, Alan R, Fischer, Rainald, Kerem, Eitan, Bell, Scott C, Loutit, Jeffery S, Dudley, Michael N, Morgan, Elizabeth E, VanDevanter, Donald R, Flume, Patrick A
Published in Journal of cystic fibrosis (01.07.2015)
Published in Journal of cystic fibrosis (01.07.2015)
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Journal Article
세프티부텐 투여 요법
GRIFFITH DAVID C, LOUTIT JEFFERY S, LOMOVSKAYA OLGA, MORGAN ELIZABETH E
Year of Publication 07.12.2023
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Year of Publication 07.12.2023
Patent
세균 감염을 치료하는 방법
GRIFFITH DAVID C, LOUTIT JEFFREY S, DUDLEY MICHAEL N, LOMOVSKAYA OLGA, MORGAN ELIZABETH E, FUSARO KAREN
Year of Publication 09.09.2019
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Year of Publication 09.09.2019
Patent
A synthetic androstene derivative and a natural androstene metabolite inhibit relapsing–remitting EAE
Offner, Halina, Zamora, Alex, Drought, Heather, Matejuk, Agata, Auci, Dominick L, Morgan, Elizabeth E, Vandenbark, Arthur A, Reading, Christopher L
Published in Journal of neuroimmunology (01.09.2002)
Published in Journal of neuroimmunology (01.09.2002)
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Journal Article
A synthetic androstene analogue inhibits collagen-induced arthritis in the mouse
Offner, Halina, Zamora, Alex, Subramanian, Sandhya, Polanczyk, Magdalena, Krogstad, Aric, Auci, Dominick L, Morgan, Elizabeth E, Reading, Christopher L
Published in Clinical immunology (Orlando, Fla.) (01.02.2004)
Published in Clinical immunology (Orlando, Fla.) (01.02.2004)
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Journal Article
Results of a phase I clinical trial of a T-cell receptor vaccine in patients with multiple sclerosis. II. Comparative analysis of TCR utilization in CSF T-cell populations before and after vaccination with a TCRV β6 CDR2 peptide
Gold, Daniel P, Smith, Richard A, Golding, Anna B, Morgan, Elizabeth E, Dafashy, Tanya, Nelson, James, Smith, Larry, Joji Diveley, Laxer, Julie A, Richieri, Steven P, Carlo, Dennis J, Brostoff, Steven W, Wilson, Darcy B
Published in Journal of neuroimmunology (01.06.1997)
Published in Journal of neuroimmunology (01.06.1997)
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Journal Article
USE OF AEROSOLIZED LEVOFLOXACIN FOR TREATING CYSTIC FIBROSIS
GRIFFITH DAVID C, DUDLEY MICHAEL N, LOMOVSKAYA OLGA, MORGAN ELIZABETH E, LOUTIT JEFFEREY S
Year of Publication 12.09.2012
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Year of Publication 12.09.2012
Patent
USE OF AEROSOLIZED ANTIBIOTICS FOR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASE
GRIFFITH DAVID C, LOUTIT JEFFERY S, BOSTIAN KEITH A, SETHI SANJAY, DUDLEY MICHAEL N, MORGAN ELIZABETH E, BERKLEY NEIL
Year of Publication 19.09.2012
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Year of Publication 19.09.2012
Patent
CEFTIBUTEN DOSING REGIMENS
Morgan, Elizabeth E, Lomovskaya, Olga, Loutit, Jeffery S, Griffith, David C
Year of Publication 20.06.2024
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Year of Publication 20.06.2024
Patent
CEFTIBUTEN DOSING REGIMENS
GRIFFITH, David C, MORGAN, Elizabeth E, LOUTIT, Jeffery S, LOMOVSKAYA, Olga
Year of Publication 14.02.2024
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Year of Publication 14.02.2024
Patent
Methods of treating bacterial infections
Morgan, Elizabeth E, Loutit, Jeffrey S, Fusaro, Karen, Lomovskaya, Olga, Dudley, Michael N, Griffith, David C
Year of Publication 30.11.2023
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Year of Publication 30.11.2023
Patent
CEFTIBUTEN DOSING REGIMENS
GRIFFITH, David C, MORGAN, Elizabeth E, LOUTIT, Jeffery S, LOMOVSKAYA, Olga
Year of Publication 21.09.2023
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Year of Publication 21.09.2023
Patent