Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers anti-multiple myeloma activity
Amodio, Nicola, Stamato, Maria Angelica, Juli, Giada, Morelli, Eugenio, Fulciniti, Mariateresa, Manzoni, Martina, Taiana, Elisa, Agnelli, Luca, Cantafio, Maria Eugenia Gallo, Romeo, Enrica, Raimondi, Lavinia, Caracciolo, Daniele, Zuccalà, Valeria, Rossi, Marco, Neri, Antonino, Munshi, Nikhil C., Tagliaferri, Pierosandro, Tassone, Pierfrancesco
Published in Leukemia (01.09.2018)
Published in Leukemia (01.09.2018)
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Targeting histone deacetylase 3 (HDAC3) in the bone marrow microenvironment inhibits multiple myeloma proliferation by modulating exosomes and IL-6 trans-signaling
Ho, Matthew, Chen, Tianzeng, Liu, Jiye, Dowling, Paul, Hideshima, Teru, Zhang, Li, Morelli, Eugenio, Camci-Unal, Gulden, Wu, Xinchen, Tai, Yu-Tzu, Wen, Kenneth, Samur, Mehmet, Schlossman, Robert L., Mazitschek, Ralph, Kavanagh, Emma L., Lindsay, Sinéad, Harada, Takeshi, McCann, Amanda, Anderson, Kenneth C., O’Gorman, Peter, Bianchi, Giada
Published in Leukemia (01.01.2020)
Published in Leukemia (01.01.2020)
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A 13 mer LNA-i-miR-221 Inhibitor Restores Drug Sensitivity in Melphalan-Refractory Multiple Myeloma Cells
Gullà, Annamaria, Di Martino, Maria Teresa, Gallo Cantafio, Maria Eugenia, Morelli, Eugenio, Amodio, Nicola, Botta, Cirino, Pitari, Maria Rita, Lio, Santo Giovanni, Britti, Domenico, Stamato, Maria Angelica, Hideshima, Teru, Munshi, Nikhil C, Anderson, Kenneth C, Tagliaferri, Pierosandro, Tassone, Pierfrancesco
Published in Clinical cancer research (01.03.2016)
Published in Clinical cancer research (01.03.2016)
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Exploiting MYC-induced PARPness to target genomic instability in multiple myeloma
Caracciolo, Daniele, Scionti, Francesca, Juli, Giada, Altomare, Emanuela, Golino, Gaetanina, Todoerti, Katia, Grillone, Katia, Riillo, Caterina, Arbitrio, Mariamena, Iannone, Michelangelo, Morelli, Eugenio, Amodio, Nicola, Di Martino, Maria Teresa, Rossi, Marco, Neri, Antonino, Tagliaferri, Pierosandro, Tassone, Pierfrancesco
Published in Haematologica (Roma) (01.01.2021)
Published in Haematologica (Roma) (01.01.2021)
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Journal Article
JunB is a key regulator of multiple myeloma bone marrow angiogenesis
Fan, Fengjuan, Malvestiti, Stefano, Vallet, Sonia, Lind, Judith, Garcia-Manteiga, Jose Manuel, Morelli, Eugenio, Jiang, Qinyue, Seckinger, Anja, Hose, Dirk, Goldschmidt, Hartmut, Stadlbauer, Andreas, Sun, Chunyan, Mei, Heng, Pecherstorfer, Martin, Bakiri, Latifa, Wagner, Erwin F., Tonon, Giovanni, Sattler, Martin, Hu, Yu, Tassone, Pierfrancesco, Jaeger, Dirk, Podar, Klaus
Published in Leukemia (01.12.2021)
Published in Leukemia (01.12.2021)
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Inhibition of miR-21 restores RANKL/OPG ratio in multiple myeloma-derived bone marrow stromal cells and impairs the resorbing activity of mature osteoclasts
Pitari, Maria Rita, Rossi, Marco, Amodio, Nicola, Botta, Cirino, Morelli, Eugenio, Federico, Cinzia, Gullà, Annamaria, Caracciolo, Daniele, Di Martino, Maria Teresa, Arbitrio, Mariamena, Giordano, Antonio, Tagliaferri, Pierosandro, Tassone, Pierfrancesco
Published in Oncotarget (29.09.2015)
Published in Oncotarget (29.09.2015)
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Journal Article
Epigenetic regulation of CD38/CD48 by KDM6A mediates NK cell response in multiple myeloma
Liu, Jiye, Xing, Lijie, Li, Jiang, Wen, Kenneth, Liu, Ning, Liu, Yuntong, Wu, Gongwei, Wang, Su, Ogiya, Daisuke, Song, Tian-Yu, Kurata, Keiji, Penailillo, Johany, Morelli, Eugenio, Wang, Tingjian, Hong, Xiaoning, Gulla, Annamaria, Tai, Yu-Tzu, Munshi, Nikhil, Richardson, Paul, Carrasco, Ruben, Hideshima, Teru, Anderson, Kenneth C.
Published in Nature communications (14.02.2024)
Published in Nature communications (14.02.2024)
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DIS3 depletion in multiple myeloma causes extensive perturbation in cell cycle progression and centrosome amplification
Favasuli, Vanessa K, Ronchetti, Domenica, Silvestris, Ilaria, Puccio, Noemi, Fabbiano, Giuseppina, Traini, Valentina, Todoerti, Katia, Erratico, Silvia, Ciarrocchi, Alessia, Fragliasso, Valentina, Giannandrea, Domenica, Tumiatti, Francesca, Chiaramonte, Raffaella, Torrente, Yvan, Finelli, Palma, Morelli, Eugenio, Munshi, Nikhil C, Bolli, Niccolò, Neri, Antonino, Taìana, Elisa
Published in Haematologica (Roma) (01.01.2024)
Published in Haematologica (Roma) (01.01.2024)
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miR17~92 restrains pro-apoptotic BIM to ensure survival of haematopoietic stem and progenitor cells
Brinkmann, Kerstin, Ng, Ashley P., de Graaf, Carolyn A., Di Rago, Ladina, Hyland, Craig D., Morelli, Eugenio, Rautela, Jai, Huntington, Nicholas D., Strasser, Andreas, Alexander, Warren S., Herold, Marco J.
Published in Cell death and differentiation (01.05.2020)
Published in Cell death and differentiation (01.05.2020)
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Journal Article
In vitro and in vivo activity of a novel locked nucleic acid (LNA)-inhibitor-miR-221 against multiple myeloma cells
Di Martino, Maria Teresa, Gullà, Annamaria, Gallo Cantafio, Maria Eugenia, Altomare, Emanuela, Amodio, Nicola, Leone, Emanuela, Morelli, Eugenio, Lio, Santo Giovanni, Caracciolo, Daniele, Rossi, Marco, Frandsen, Niels M, Tagliaferri, Pierosandro, Tassone, Pierfrancesco
Published in PloS one (21.02.2014)
Published in PloS one (21.02.2014)
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Inhibition of Haspin Kinase Promotes Cell-Intrinsic and Extrinsic Antitumor Activity
Melms, Johannes C, Vallabhaneni, Sreeram, Mills, Caitlin E, Yapp, Clarence, Chen, Jia-Yun, Morelli, Eugenio, Waszyk, Patricia, Kumar, Sushil, Deming, Derrick, Moret, Nienke, Rodriguez, Steven, Subramanian, Kartik, Rogava, Meri, Cartwright, Adam N R, Luoma, Adrienne, Mei, Shaolin, Brinker, Titus J, Miller, David M, Spektor, Alexander, Schadendorf, Dirk, Riggi, Nicolo, Wucherpfennig, Kai W, Sorger, Peter K, Izar, Benjamin
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Promises and Challenges of Immunogenic Chemotherapy in Multiple Myeloma
Johnstone, Megan, Vinaixa, Delaney, Turi, Marcello, Morelli, Eugenio, Anderson, Kenneth Carl, Gulla, Annamaria
Published in Cells (Basel, Switzerland) (01.08.2022)
Published in Cells (Basel, Switzerland) (01.08.2022)
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Molecular targets for the treatment of multiple myeloma
Rossi, Marco, Di Martino, Maria Teresa, Morelli, Eugenio, Leotta, Marzia, Rizzo, Antonietta, Grimaldi, Anna, Misso, Gabriella, Tassone, Pierfrancesco, Caraglia, Michele
Published in Current cancer drug targets (01.09.2012)
Published in Current cancer drug targets (01.09.2012)
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GPER1 Activation Exerts Anti-Tumor Activity in Multiple Myeloma
Gallo Cantafio, Maria Eugenia, Torcasio, Roberta, Scionti, Francesca, Mesuraca, Maria, Ronchetti, Domenica, Pistoni, Mariaelena, Bellizzi, Dina, Passarino, Giuseppe, Morelli, Eugenio, Neri, Antonino, Viglietto, Giuseppe, Amodio, Nicola
Published in Cells (Basel, Switzerland) (01.09.2023)
Published in Cells (Basel, Switzerland) (01.09.2023)
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Therapeutic activation of G protein-coupled estrogen receptor 1 in Waldenström Macroglobulinemia
Morelli, Eugenio, Hunter, Zachary R., Fulciniti, Mariateresa, Gullà, Annamaria, Perrotta, Ida Daniela, Zuccalà, Valeria, Federico, Cinzia, Juli, Giada, Manzoni, Martina, Ronchetti, Domenica, Romeo, Enrica, Gallo Cantafio, Maria Eugenia, Soncini, Debora, Maltese, Lorenza, Rossi, Marco, Roccaro, Aldo M., Cea, Michele, Tassone, Pierfrancesco, Neri, Antonino, Treon, Steven C., Munshi, Nikhil C., Viglietto, Giuseppe, Amodio, Nicola
Published in Experimental hematology & oncology (12.09.2022)
Published in Experimental hematology & oncology (12.09.2022)
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Therapeutic targeting of miR-29b/HDAC4 epigenetic loop in multiple myeloma
Amodio, Nicola, Stamato, Maria Angelica, Gullà, Anna Maria, Morelli, Eugenio, Romeo, Enrica, Raimondi, Lavinia, Pitari, Maria Rita, Ferrandino, Ida, Misso, Gabriella, Caraglia, Michele, Perrotta, Ida, Neri, Antonino, Fulciniti, Mariateresa, Rolfo, Christian, Anderson, Kenneth C, Munshi, Nikhil C, Tagliaferri, Pierosandro, Tassone, Pierfrancesco
Published in Molecular cancer therapeutics (01.06.2016)
Published in Molecular cancer therapeutics (01.06.2016)
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RAD51 Is Required for the Occupancy of Replication Licensing Factors on the Myeloma Genome
Zhao, Jiangning, Talluri, Srikanth, Kumar, Subodh, Morelli, Eugenio, Potluri, Lakshmi B., Shammas, Masood A., Munshi, Nikhil C
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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BRD9 Degradation Disrupts Ribosome Biogenesis in Multiple Myeloma
Kurata, Keiji, Samur, Mehmet K, Liow, Priscilla, Wen, Kenneth, Yamamoto, Leona, Liu, Jiye, Morelli, Eugenio, Gulla, Annamaria, Tai, Yu-Tzu, Qi, Jun, Hideshima, Teru, Anderson, Kenneth C
Published in Clinical cancer research (01.05.2023)
Published in Clinical cancer research (01.05.2023)
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Journal Article
MicroRNAs: Novel Crossroads between Myeloma Cells and the Bone Marrow Microenvironment
Amodio, Nicola, Tagliaferri, Pierosandro, Giavaresi, Gianluca, Morelli, Eugenio, De Luca, Angela, Raimondi, Lavinia, Tassone, Pierfrancesco
Published in BioMed research international (01.01.2016)
Published in BioMed research international (01.01.2016)
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