Intratumoral IL12 mRNA Therapy Promotes TH1 Transformation of the Tumor Microenvironment
Hewitt, Susannah L, Bailey, Dyane, Zielinski, John, Apte, Ameya, Musenge, Faith, Karp, Russell, Burke, Shannon, Garcon, Fabien, Mishra, Ankita, Gurumurthy, Sushma, Watkins, Amanda, Arnold, Kristen, Moynihan, James, Clancy-Thompson, Eleanor, Mulgrew, Kathy, Adjei, Grace, Deschler, Katharina, Potz, Darren, Moody, Gordon, Leinster, David A, Novick, Steve, Sulikowski, Michal, Bagnall, Chris, Martin, Philip, Lapointe, Jean-Martin, Si, Han, Morehouse, Chris, Sedic, Maja, Wilkinson, Robert W, Herbst, Ronald, Frederick, Joshua P, Luheshi, Nadia
Published in Clinical cancer research (01.12.2020)
Published in Clinical cancer research (01.12.2020)
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Efficacy and Safety of MEDI2070, an Antibody Against Interleukin 23, Patients With Moderate to Severe Crohn's Disease: a Phase 2a Study
Sands, Bruce E., MD, Chen, Jingjing, PhD, Feagan, Brian G., MD, Penney, Mark, PhD, Rees, William A., Ph.D, Danese, Silvio, MD, PhD, Higgins, Peter D.R., MD, PhD, Newbold, Paul, PhD, Faggioni, Raffaella, PhD, Patra, Kaushik, PhD, Li, Jing, PhD, Klekotka, Paul, MD, PhD, Morehouse, Chris, MS, Pulkstenis, Erik, PhD, Drappa, Jörn, MD, PhD, van der Merwe, René, MBChB, Gasser, Robert A., MD
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2017)
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Journal Article
Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer
Jiang, Liyan, Huang, Jiaqi, Higgs, Brandon W, Hu, Zhibin, Xiao, Zhan, Yao, Xin, Conley, Sarah, Zhong, Haihong, Liu, Zheng, Brohawn, Philip, Shen, Dong, Wu, Song, Ge, Xiaoxiao, Jiang, Yue, Zhao, Yizhuo, Lou, Yuqing, Morehouse, Chris, Zhu, Wei, Sebastian, Yinong, Czapiga, Meggan, Oganesyan, Vaheh, Fu, Haihua, Niu, Yanjie, Zhang, Wei, Streicher, Katie, Tice, David, Zhao, Heng, Zhu, Meng, Xu, Lin, Herbst, Ronald, Su, Xinying, Gu, Yi, Li, Shyoung, Huang, Lihua, Gu, Jianren, Han, Baohui, Jallal, Bahija, Shen, Hongbing, Yao, Yihong
Published in PLoS genetics (19.04.2016)
Published in PLoS genetics (19.04.2016)
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Journal Article
Type I IFNs Regulate Inflammation, Vasculopathy, and Fibrosis in Chronic Cutaneous Graft-versus-Host Disease
Delaney, Tracy A, Morehouse, Chris, Brohawn, P Zachary, Groves, Christopher, Colonna, Marco, Yao, Yihong, Sanjuan, Miguel, Coyle, Anthony J
Published in The Journal of immunology (1950) (01.07.2016)
Published in The Journal of immunology (1950) (01.07.2016)
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Journal Article
Mycophenolic acid differentially impacts B cell function depending on the stage of differentiation
Karnell, Jodi L, Karnell, 3rd, Fredrick G, Stephens, Geoffrey L, Rajan, Bhargavi, Morehouse, Chris, Li, Ying, Swerdlow, Bonnie, Wilson, Mildred, Goldbach-Mansky, Raphaela, Groves, Christopher, Coyle, Anthony J, Herbst, Ronald, Ettinger, Rachel
Published in The Journal of immunology (1950) (01.10.2011)
Published in The Journal of immunology (1950) (01.10.2011)
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Journal Article
Altered expression of insulin receptor isoforms in breast cancer
Huang, Jiaqi, Morehouse, Chris, Streicher, Katie, Higgs, Brandon W, Gao, Jin, Czapiga, Meggan, Boutrin, Anmarie, Zhu, Wei, Brohawn, Philip, Chang, Yong, Viner, Jaye, LaVallee, Theresa, Richman, Laura, Jallal, Bahija, Yao, Yihong
Published in PloS one (26.10.2011)
Published in PloS one (26.10.2011)
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Journal Article
High-throughput RNA sequencing reveals distinct gene signatures in active IgG4-related disease
Higgs, Brandon W., Liu, Yanying, Guo, Jianping, Sebastian, Yinong, Morehouse, Chris, Zhu, Wei, Ren, Limin, Liu, Mengru, Du, Yan, Yu, Guangyan, Dong, Lingli, Hua, Hong, Wei, Pan, Wang, Yi, Wang, Zhengang, Yao, Yihong, Li, Zhan-Guo
Published in Scientific reports (14.12.2017)
Published in Scientific reports (14.12.2017)
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Journal Article
Anti-PD-1 monoclonal antibody MEDI0680 in a phase I study of patients with advanced solid malignancies
Naing, Aung, Infante, Jeffrey, Goel, Sanjay, Burris, Howard, Black, Chelsea, Marshall, Shannon, Achour, Ikbel, Barbee, Susannah, May, Rena, Morehouse, Chris, Pollizzi, Kristen, Song, Xuyang, Steele, Keith, Elgeioushi, Nairouz, Walcott, Farzana, Karakunnel, Joyson, LoRusso, Patricia, Weise, Amy, Eder, Joseph, Curti, Brendan, Oberst, Michael
Published in Journal for immunotherapy of cancer (22.08.2019)
Published in Journal for immunotherapy of cancer (22.08.2019)
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Journal Article
A whole genome transcriptional analysis of the early immune response induced by live attenuated and inactivated influenza vaccines in young children
Zhu, Wei, Higgs, Brandon W, Morehouse, Chris, Streicher, Katie, Ambrose, Christopher S, Woo, Jennifer, Kemble, George W, Jallal, Bahija, Yao, Yihong
Published in Vaccine (01.04.2010)
Published in Vaccine (01.04.2010)
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Journal Article
Type I interferon: potential therapeutic target for psoriasis?
Yao, Yihong, Richman, Laura, Morehouse, Chris, de los Reyes, Melissa, Higgs, Brandon W, Boutrin, Anmarie, White, Barbara, Coyle, Anthony, Krueger, James, Kiener, Peter A, Jallal, Bahija
Published in PloS one (16.07.2008)
Published in PloS one (16.07.2008)
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Journal Article
The CEA/CD3-bispecific antibody MEDI-565 (MT111) binds a nonlinear epitope in the full-length but not a short splice variant of CEA
Peng, Li, Oberst, Michael D, Huang, Jiaqi, Brohawn, Philip, Morehouse, Chris, Lekstrom, Kristen, Baeuerle, Patrick A, Wu, Herren, Yao, Yihong, Coats, Steven R, Dall'Acqua, William, Damschroder, Melissa, Hammond, Scott A
Published in PloS one (04.05.2012)
Published in PloS one (04.05.2012)
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Journal Article
Genomic signatures characterize leukocyte infiltration in myositis muscles
Zhu, Wei, Streicher, Katie, Shen, Nan, Higgs, Brandon W, Morehouse, Chris, Greenlees, Lydia, Amato, Anthony A, Ranade, Koustubh, Richman, Laura, Fiorentino, David, Jallal, Bahija, Greenberg, Steven A, Yao, Yihong
Published in BMC medical genomics (21.11.2012)
Published in BMC medical genomics (21.11.2012)
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Journal Article
Low frequency KRAS mutations in colorectal cancer patients and the presence of multiple mutations in oncogenic drivers in non-small cell lung cancer patients
Jiang, Liyan, Huang, Jiaqi, Morehouse, Chris, Zhu, Wei, Korolevich, Susana, Sui, Dan, Ge, Xiaoxiao, Lehmann, Kim, Liu, Zheng, Kiefer, Christine, Czapiga, Meggan, Su, Xinying, Brohawn, Philip, Gu, Yi, Higgs, Brandon W, Yao, Yihong
Published in Cancer genetics (01.09.2013)
Published in Cancer genetics (01.09.2013)
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Journal Article
Type I Interferon Inhibition of MicroRNA‐146a Maturation Through Up‐Regulation of Monocyte Chemotactic Protein–Induced Protein 1 in Systemic Lupus Erythematosus
Qu, Bo, Cao, Jianchang, Zhang, Feifei, Cui, Huijuan, Teng, Jialin, Li, Jia, Liu, Zheng, Morehouse, Chris, Jallal, Bahija, Tang, Yuanjia, Guo, Qiang, Yao, Yihong, Shen, Nan
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2015)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2015)
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Journal Article
Early incidence of immune-related adverse events (irAEs) predicts efficacy in patients (pts) with solid tumors treated with immune-checkpoint inhibitors (ICIs)
Morehouse, Chris, Abdullah, Shaad Essa, Gao, Chen, Dar, Mohammed M., Ranade, Koustubh, Higgs, Brandon W.
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
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Journal Article
A phase 1b clinical trial evaluating sifalimumab, an anti-IFN-α monoclonal antibody, shows target neutralisation of a type I IFN signature in blood of dermatomyositis and polymyositis patients
Higgs, Brandon W, Zhu, Wei, Morehouse, Chris, White, Wendy I, Brohawn, Philip, Guo, Xiang, Rebelatto, Marlon, Le, Chenxiong, Amato, Anthony, Fiorentino, David, Greenberg, Steven A, Drappa, Jorn, Richman, Laura, Greth, Warren, Jallal, Bahija, Yao, Yihong
Published in Annals of the rheumatic diseases (01.01.2014)
Published in Annals of the rheumatic diseases (01.01.2014)
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Journal Article
Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway
Higgs, Brandon W, Liu, Zheng, White, Barbara, Zhu, Wei, White, Wendy I, Morehouse, Chris, Brohawn, Philip, Kiener, Peter A, Richman, Laura, Fiorentino, David, Greenberg, Steven A, Jallal, Bahija, Yao, Yihong
Published in Annals of the rheumatic diseases (01.11.2011)
Published in Annals of the rheumatic diseases (01.11.2011)
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Journal Article
Gene expression analysis of tumor biopsies from a trial of durvalumab to identify subsets of NSCLC with shared immune pathways
Streicher, Katie, Morehouse, Chris, Sebastian, Yinong, Kuziora, Michael, Higgs, Brandon W., Ranade, Koustubh
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Journal Article
Prognostic Significance of Liver Metastasis in Durvalumab-Treated Lung Cancer Patients
Sridhar, Sriram, Paz-Ares, Luis, Liu, Hao, Shen, Kui, Morehouse, Chris, Rizvi, Naiyer, Segal, Neil H., Jin, Xiaoping, Zheng, Yanan, Narwal, Rajesh, Gupta, Ashok, Dennis, Phillip A., Ye, Jiabu, Mukhopadhyay, Pralay, Higgs, Brandon W., Ranade, Koustubh
Published in Clinical lung cancer (01.11.2019)
Published in Clinical lung cancer (01.11.2019)
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