A dual read-out assay to evaluate the potency of compounds active against Mycobacterium tuberculosis
Ollinger, Juliane, Bailey, Mai Ann, Moraski, Garrett C, Casey, Allen, Florio, Stephanie, Alling, Torey, Miller, Marvin J, Parish, Tanya
Published in PloS one (04.04.2013)
Published in PloS one (04.04.2013)
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Journal Article
Targeting the Mycobacterium ulcerans cytochrome bc 1 :aa 3 for the treatment of Buruli ulcer
Scherr, Nicole, Bieri, Raphael, Thomas, Sangeeta S, Chauffour, Aurélie, Nitin Pal Kalia, Schneide, Paul, Ruf, Marie-Thérèse, Lamelas, Araceli, Manimekalai, Malathy S S, Grüber, Gerhard, Ishii, Norihisa, Suzuki, Koichi, Tanner, Marcel, Moraski, Garrett C, Miller, Marvin J, Witschel, Matthias, Jarlier, Vincent, Pluschke, Gerd, Pethe, Kevin
Published in Nature communications (01.12.2018)
Published in Nature communications (01.12.2018)
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Journal Article
Dual inhibition of the terminal oxidases eradicates antibiotic‐tolerant Mycobacterium tuberculosis
Lee, Bei Shi, Hards, Kiel, Engelhart, Curtis A, Hasenoehrl, Erik J, Kalia, Nitin P, Mackenzie, Jared S, Sviriaeva, Ekaterina, Chong, Shi Min Sherilyn, Manimekalai, Malathy Sony S, Koh, Vanessa H, Chan, John, Xu, Jiayong, Alonso, Sylvie, Miller, Marvin J, Steyn, Adrie J C, Grüber, Gerhard, Schnappinger, Dirk, Berney, Michael, Cook, Gregory M, Moraski, Garrett C, Pethe, Kevin
Published in EMBO molecular medicine (11.01.2021)
Published in EMBO molecular medicine (11.01.2021)
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Journal Article
Structure-Based Mechanism for Oxidative Decarboxylation Reactions Mediated by Amino Acids and Heme Propionates in Coproheme Decarboxylase (HemQ)
Celis, Arianna I, Gauss, George H, Streit, Bennett R, Shisler, Krista, Moraski, Garrett C, Rodgers, Kenton R, Lukat-Rodgers, Gudrun S, Peters, John W, DuBois, Jennifer L
Published in Journal of the American Chemical Society (08.02.2017)
Published in Journal of the American Chemical Society (08.02.2017)
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Journal Article
Bactericidal activity of an imidazo[1, 2-a]pyridine using a mouse M. tuberculosis infection model
Cheng, Yong, Moraski, Garrett C, Cramer, Jeffrey, Miller, Marvin J, Schorey, Jeffrey S
Published in PloS one (31.01.2014)
Published in PloS one (31.01.2014)
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Journal Article
Decarboxylation involving a ferryl, propionate, and a tyrosyl group in a radical relay yields heme b
Streit, Bennett R., Celis, Arianna I., Moraski, Garrett C., Shisler, Krista A., Shepard, Eric M., Rodgers, Kenton R., Lukat-Rodgers, Gudrun S., DuBois, Jennifer L.
Published in The Journal of biological chemistry (16.03.2018)
Published in The Journal of biological chemistry (16.03.2018)
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Journal Article
Structure–activity relationship of new anti-tuberculosis agents derived from oxazoline and oxazole benzyl esters
Moraski, Garrett C., Chang, Mayland, Villegas-Estrada, Adriel, Franzblau, Scott G., Möllmann, Ute, Miller, Marvin J.
Published in European journal of medicinal chemistry (01.05.2010)
Published in European journal of medicinal chemistry (01.05.2010)
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Journal Article
Intracellular and in vivo evaluation of imidazo[2,1-b]thiazole-5-carboxamide anti-tuberculosis compounds
Moraski, Garrett C, Deboosère, Nathalie, Marshall, Kate L, Weaver, Heath A, Vandeputte, Alexandre, Hastings, Courtney, Woolhiser, Lisa, Lenaerts, Anne J, Brodin, Priscille, Miller, Marvin J
Published in PloS one (06.01.2020)
Published in PloS one (06.01.2020)
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Journal Article
Syntheses and Structure-Activity Relationships of N -Phenethyl-Quinazolin-4-yl-Amines as Potent Inhibitors of Cytochrome bd Oxidase in Mycobacterium tuberculosis
Hopfner, Sarah M, Lee, Bei Shi, Kalia, Nitin P, Miller, Marvin J, Pethe, Kevin, Moraski, Garrett C
Published in Applied sciences (01.10.2021)
Published in Applied sciences (01.10.2021)
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Journal Article
Targeting the Mycobacterium ulcerans cytochrome bc1:aa3 for the treatment of Buruli ulcer
Scherr, Nicole, Bieri, Raphael, Thomas, Sangeeta S., Chauffour, Aurélie, Kalia, Nitin Pal, Schneide, Paul, Ruf, Marie-Thérèse, Lamelas, Araceli, Manimekalai, Malathy S. S., Grüber, Gerhard, Ishii, Norihisa, Suzuki, Koichi, Tanner, Marcel, Moraski, Garrett C., Miller, Marvin J., Witschel, Matthias, Jarlier, Vincent, Pluschke, Gerd, Pethe, Kevin
Published in Nature communications (18.12.2018)
Published in Nature communications (18.12.2018)
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Journal Article
Imidazopyridine Compounds Inhibit Mycobacterial Growth by Depleting ATP Levels
O'Malley, Theresa, Alling, Torey, Early, Julie V, Wescott, Heather A, Kumar, Anuradha, Moraski, Garrett C, Miller, Marvin J, Masquelin, Thierry, Hipskind, Philip A, Parish, Tanya
Published in Antimicrobial agents and chemotherapy (01.06.2018)
Published in Antimicrobial agents and chemotherapy (01.06.2018)
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Journal Article
Generation and exploration of new classes of antitubercular agents: The optimization of oxazolines, oxazoles, thiazolines, thiazoles to imidazo[1,2-a]pyridines and isomeric 5,6-fused scaffolds
Moraski, Garrett C., Markley, Lowell D., Chang, Mayland, Cho, Sanghyun, Franzblau, Scott G., Hwang, Chang Hwa, Boshoff, Helena, Miller, Marvin J.
Published in Bioorganic & medicinal chemistry (01.04.2012)
Published in Bioorganic & medicinal chemistry (01.04.2012)
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Journal Article
Thiolates Chemically Induce Redox Activation of BTZ043 and Related Potent Nitroaromatic Anti-Tuberculosis Agents
Tiwari, Rohit, Moraski, Garrett C, Krchňák, Viktor, Miller, Patricia A, Colon-Martinez, Mariangelli, Herrero, Eliza, Oliver, Allen G, Miller, Marvin J
Published in Journal of the American Chemical Society (06.03.2013)
Published in Journal of the American Chemical Society (06.03.2013)
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Journal Article
N-((1-Benzyl-1H-1,2,3-triazol-4-yl)methyl)arylamide as a New Scaffold that Provides Rapid Access to Antimicrotubule Agents: Synthesis and Evaluation of Antiproliferative Activity Against Select Cancer Cell Lines
Stefely, Jonathan A, Palchaudhuri, Rahul, Miller, Patricia A, Peterson, Rebecca J, Moraski, Garrett C, Hergenrother, Paul J, Miller, Marvin J
Published in Journal of medicinal chemistry (22.04.2010)
Published in Journal of medicinal chemistry (22.04.2010)
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Journal Article
Advent of Imidazo[1,2-a]pyridine-3-carboxamides with Potent Multi- and Extended Drug Resistant Antituberculosis Activity
Moraski, Garrett C, Markley, Lowell D, Hipskind, Philip A, Boshoff, Helena, Cho, Sanghyun, Franzblau, Scott G, Miller, Marvin J
Published in ACS medicinal chemistry letters (09.06.2011)
Published in ACS medicinal chemistry letters (09.06.2011)
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